STRINGSTRING
MECP2 MECP2 PLD6 PLD6 MBTPS2 MBTPS2 FARP2 FARP2 FEM1B FEM1B NR4A2 NR4A2 EDN1 EDN1 GDF11 GDF11 EXT1 EXT1 WASHC5 WASHC5 M3XQH2_MUSPF M3XQH2_MUSPF BFSP1 BFSP1 RB1 RB1 DDIT3 DDIT3 BRCA2 BRCA2 TDRD1 TDRD1 BTK BTK IFT80 IFT80 SRRM4 SRRM4 TDRKH TDRKH HES1 HES1 SCARF2 SCARF2 KCNMA1 KCNMA1 SLC26A8 SLC26A8 LYL1 LYL1 ROPN1 ROPN1 ELSPBP1 ELSPBP1 M3XZ70_MUSPF M3XZ70_MUSPF ALDH1A2 ALDH1A2 CCL19 CCL19 TMEM79 TMEM79 M3YQU9_MUSPF M3YQU9_MUSPF M3XZV8_MUSPF M3XZV8_MUSPF SNX10 SNX10 ZBTB7A ZBTB7A HOXA5 HOXA5 ARCN1 ARCN1 CDH5 CDH5 GHRHR GHRHR KDR KDR TDRD5 TDRD5 CBFB CBFB GBA GBA THBS3 THBS3 ANGPTL8 ANGPTL8 RECK RECK GPAT4 GPAT4 CABYR CABYR REC8 REC8 ERCC2 ERCC2 CATSPERD CATSPERD BMP2 BMP2 RERE RERE HIF1A HIF1A CCR6 CCR6 B4GALT6 B4GALT6 EDNRA EDNRA CFTR CFTR LGI4 LGI4 NSUN2 NSUN2 SLC24A4 SLC24A4 GLDN GLDN SEMA4D SEMA4D MTHFSD MTHFSD CDC25B CDC25B C1QL1 C1QL1 TGFB3 TGFB3 BHLHA15 BHLHA15 CDK5R1 CDK5R1 PHOSPHO2 PHOSPHO2 LOC101680718 LOC101680718 SLC26A3 SLC26A3 NRCAM NRCAM TRPC4AP TRPC4AP AXL AXL TGFB1 TGFB1 B4GALT5 B4GALT5 IL21 IL21 SCLT1 SCLT1 RET RET ACTL6A ACTL6A KCNIP2 KCNIP2 KCNIP4 KCNIP4 FEV FEV GATA3 GATA3 FOXA1 FOXA1 IL15 IL15 EPHA8 EPHA8 SOX8 SOX8 ABHD2 ABHD2 CATSPER4 CATSPER4 EPO EPO CATSPERE CATSPERE ACTL6B ACTL6B CCDC154 CCDC154 YTHDF2 YTHDF2 PHOSPHO1 PHOSPHO1 HOXB13 HOXB13 PTH1R PTH1R WNT1 WNT1 L3MBTL3 L3MBTL3 PLA2G10 PLA2G10 SLC26A6 SLC26A6 NF1 NF1 GALK1 GALK1 ENSMPUP00000013708 ENSMPUP00000013708 DAG1 DAG1 TDRD15 TDRD15 M3YQ96_MUSPF M3YQ96_MUSPF FLVCR1 FLVCR1 SCARF1 SCARF1 DMC1 DMC1 TUSC2 TUSC2 SOX10 SOX10 PLA2G3 PLA2G3 EFCAB9 EFCAB9 RUNX2 RUNX2 TDRD6 TDRD6 TAL1 TAL1 EPAS1 EPAS1 IGF1 IGF1 IQCF5 IQCF5 IQCF1 IQCF1 CNTN2 CNTN2 PDE3A PDE3A ROPN1L ROPN1L MAEA MAEA VSX1 VSX1 FBXO5 FBXO5 CATSPER2 CATSPER2 EPB42 EPB42 TRIP13 TRIP13 CATSPER3 CATSPER3 FOXO3 FOXO3 BFSP2 BFSP2 NOM1 NOM1 G6PD G6PD ANKRD17 ANKRD17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (484 aa)
PLD6Phospholipase D family member 6. (225 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (604 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1062 aa)
FEM1BFem-1 homolog B. (627 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
EDN1Endothelin 1. (202 aa)
GDF11Growth differentiation factor 11. (404 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
WASHC5WASH complex subunit 5. (1159 aa)
M3XQH2_MUSPFUncharacterized protein. (130 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (638 aa)
RB1RB transcriptional corepressor 1. (948 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
BRCA2BRCA2 DNA repair associated. (3466 aa)
TDRD1Tudor domain containing 1. (1182 aa)
BTKTyrosine-protein kinase. (659 aa)
IFT80Intraflagellar transport 80. (766 aa)
SRRM4Serine/arginine repetitive matrix 4. (603 aa)
TDRKHTudor and KH domain containing. (560 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
SCARF2Scavenger receptor class F member 2. (861 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1020 aa)
SLC26A8Testis anion transporter 1. (965 aa)
LYL1LYL1 basic helix-loop-helix family member. (279 aa)
ROPN1Uncharacterized protein. (212 aa)
ELSPBP1Epididymal sperm binding protein 1. (248 aa)
M3XZ70_MUSPFUncharacterized protein. (128 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
CCL19C-C motif chemokine. (108 aa)
TMEM79Transmembrane protein 79. (395 aa)
M3YQU9_MUSPFHistone H3; Belongs to the histone H3 family. (136 aa)
M3XZV8_MUSPFCyclic nucleotide-binding domain-containing protein. (857 aa)
SNX10Sorting nexin 10. (201 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (550 aa)
HOXA5Homeobox A5. (270 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
TDRD5Tudor domain containing 5. (1046 aa)
CBFBCore-binding factor subunit beta. (182 aa)
GBAGlucosylceramidase. (547 aa)
THBS3Thrombospondin 3. (956 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (969 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
CABYRCalcium binding tyrosine phosphorylation regulated. (493 aa)
REC8REC8 meiotic recombination protein. (593 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
CATSPERDCation channel sperm associated auxiliary subunit delta. (684 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
REREArginine-glutamic acid dipeptide repeats. (1553 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
LGI4Leucine rich repeat LGI family member 4. (537 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (720 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (603 aa)
GLDNGliomedin. (490 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (395 aa)
CDC25BCell division cycle 25B. (515 aa)
C1QL1Complement C1q like 1. (243 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
LOC101680718Histone H3; Belongs to the histone H3 family. (136 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
NRCAMNeuronal cell adhesion molecule. (1215 aa)
TRPC4APTransient receptor potential cation channel subfamily C member 4 associated protein. (796 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (344 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
SCLT1Sodium channel and clathrin linker 1. (646 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1028 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
KCNIP2Kv channel-interacting protein 2; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. Essential for the expression of I(To) currents in the heart. Required for normal protein levels of KCND2 in the heart ventricle (By similarity); Belongs to the recoverin family. (252 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (213 aa)
FEVFEV transcription factor, ETS family member. (247 aa)
GATA3GATA binding protein 3. (444 aa)
FOXA1Forkhead box A1. (501 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
EPHA8EPH receptor A8. (930 aa)
SOX8SRY-box transcription factor 8. (377 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
CATSPER4Cation channel sperm associated 4. (449 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
CATSPERECatsper channel auxiliary subunit epsilon. (775 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
CCDC154Coiled-coil domain containing 154. (669 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (580 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (305 aa)
HOXB13Homeobox B13. (290 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (596 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
PLA2G10Phospholipase A(2). (159 aa)
SLC26A6Solute carrier family 26 member 6. (761 aa)
NF1Neurofibromin 1. (2815 aa)
GALK1Galactokinase 1. (392 aa)
ENSMPUP00000013708annotation not available (136 aa)
DAG1Dystroglycan 1. (891 aa)
TDRD15Tudor domain containing 15. (2086 aa)
M3YQ96_MUSPFEXPERA domain-containing protein. (230 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
SCARF1Scavenger receptor class F member 1. (823 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (288 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
SOX10SRY-box transcription factor 10. (602 aa)
PLA2G3Phospholipase A2 group III. (510 aa)
EFCAB9EF-hand calcium binding domain 9. (215 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (507 aa)
TDRD6Tudor domain containing 6. (2120 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (346 aa)
EPAS1Endothelial PAS domain protein 1. (868 aa)
IGF1Insulin like growth factor 1. (153 aa)
IQCF5IQ motif containing F5. (153 aa)
IQCF1IQ motif containing F1. (209 aa)
CNTN2Contactin 2. (1077 aa)
PDE3APhosphodiesterase. (1137 aa)
ROPN1LRhophilin associated tail protein 1 like. (218 aa)
MAEAMacrophage erythroblast attacher. (434 aa)
VSX1Visual system homeobox 1. (363 aa)
FBXO5F-box protein 5. (386 aa)
CATSPER2Cation channel sperm associated 2. (533 aa)
EPB42Erythrocyte membrane protein band 4.2. (692 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (434 aa)
CATSPER3Cation channel sperm associated 3. (367 aa)
FOXO3Forkhead box O3. (671 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
NOM1Nucleolar protein with MIF4G domain 1. (689 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
ANKRD17Ankyrin repeat domain 17. (2491 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (16%) [HD]