(13 nodes) Nephron tubule formation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GATA3	GATA binding protein 3. (444 aa)
	IRX3	Iroquois homeobox 3. (502 aa)
	M3Y0D8_MUSPF	Uncharacterized protein. (356 aa)
	IRX1	Iroquois homeobox 1. (319 aa)
	IRX2	Iroquois homeobox 2. (391 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	PAX8	Paired box 8. (462 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	SOX9	SRY-box transcription factor 9. (522 aa)
	GDNF	Glial cell derived neurotrophic factor. (211 aa)
	SOX8	SRY-box transcription factor 8. (377 aa)
	GREM1	Gremlin. (184 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GDNF	WNT9B	ENSMPUP00000014777	ENSMPUP00000008216	Glial cell derived neurotrophic factor.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.521
IRX1	IRX2	ENSMPUP00000007583	ENSMPUP00000007592	Iroquois homeobox 1.	Iroquois homeobox 2.	0.443
IRX1	SOX9	ENSMPUP00000007583	ENSMPUP00000014195	Iroquois homeobox 1.	SRY-box transcription factor 9.	0.476
IRX2	IRX1	ENSMPUP00000007592	ENSMPUP00000007583	Iroquois homeobox 2.	Iroquois homeobox 1.	0.443
IRX2	IRX3	ENSMPUP00000007592	ENSMPUP00000003329	Iroquois homeobox 2.	Iroquois homeobox 3.	0.510
IRX3	IRX2	ENSMPUP00000003329	ENSMPUP00000007592	Iroquois homeobox 3.	Iroquois homeobox 2.	0.510
PAX8	WNT9B	ENSMPUP00000009436	ENSMPUP00000008216	Paired box 8.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.632
SOX9	IRX1	ENSMPUP00000014195	ENSMPUP00000007583	SRY-box transcription factor 9.	Iroquois homeobox 1.	0.476
WNT6	WNT9B	ENSMPUP00000016447	ENSMPUP00000008216	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.561
WNT9B	GDNF	ENSMPUP00000008216	ENSMPUP00000014777	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Glial cell derived neurotrophic factor.	0.521
WNT9B	PAX8	ENSMPUP00000008216	ENSMPUP00000009436	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Paired box 8.	0.632
WNT9B	WNT6	ENSMPUP00000008216	ENSMPUP00000016447	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.561