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EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
OSR1 | Odd-skipped related transcription factor 1. (267 aa) | ||||
GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
PTCH1 | Patched 1. (1386 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (395 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |