(22 nodes) Regulation of neutrophil chemotaxis network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
	TNFAIP6	TNF alpha induced protein 6. (277 aa)
	IL23A	Interleukin 23 subunit alpha. (195 aa)
	BST1	Bone marrow stromal cell antigen 1. (307 aa)
	MOSPD2	Motile sperm domain containing 2. (518 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1013 aa)
	MCU	Mitochondrial calcium uniporter. (350 aa)
	RIPOR2	PL48 domain-containing protein. (1141 aa)
	CCL19	C-C motif chemokine. (108 aa)
	CCL21	SCY domain-containing protein. (137 aa)
	THBS4	Thrombospondin 4. (964 aa)
	NCKAP1L	NCK associated protein 1 like. (1134 aa)
	JAM3	Junctional adhesion molecule 3. (305 aa)
	C1QBP	Complement C1q binding protein. (272 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	CD74	CD74 molecule. (279 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	MPP1	Membrane palmitoylated protein 1; Belongs to the MAGUK family. (450 aa)
	SLIT2	Slit guidance ligand 2. (1539 aa)
	C5AR2	Complement component 5a receptor 2. (337 aa)
	C5AR1	Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	C3AR1	Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (479 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL19	CCL21	ENSMPUP00000004471	ENSMPUP00000004488	C-C motif chemokine.	SCY domain-containing protein.	0.933
CCL19	CCR7	ENSMPUP00000004471	ENSMPUP00000014564	C-C motif chemokine.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.999
CCL21	CCL19	ENSMPUP00000004488	ENSMPUP00000004471	SCY domain-containing protein.	C-C motif chemokine.	0.933
CCL21	CCR7	ENSMPUP00000004488	ENSMPUP00000014564	SCY domain-containing protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.999
CCR7	CCL19	ENSMPUP00000014564	ENSMPUP00000004471	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.999
CCR7	CCL21	ENSMPUP00000014564	ENSMPUP00000004488	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.999
NCKAP1L	RAC2	ENSMPUP00000005592	ENSMPUP00000012588	NCK associated protein 1 like.	Rac family small GTPase 2.	0.961
RAC2	NCKAP1L	ENSMPUP00000012588	ENSMPUP00000005592	Rac family small GTPase 2.	NCK associated protein 1 like.	0.961