STRINGSTRING
VEGFA VEGFA ITGB1BP1 ITGB1BP1 CARD10 CARD10 ABL1 ABL1 HMOX1 HMOX1 NOTCH1 NOTCH1 NR2E1 NR2E1 HDAC5 HDAC5 ANXA1 ANXA1 MMRN2 MMRN2 DLL4 DLL4 THBS1 THBS1 HDAC7 HDAC7 STARD13 STARD13 SRPX2 SRPX2 TBXA2R TBXA2R FBXW9 FBXW9 SPRED1 SPRED1 FBXW7 FBXW7 RHOJ RHOJ FGFBP1 FGFBP1 FGF2 FGF2 PDCD10 PDCD10 JCAD JCAD KDR KDR CIB1 CIB1 MAP3K3 MAP3K3 MEOX2 MEOX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CARD10Caspase recruitment domain family, member 10. (1028 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
NOTCH1Notch receptor 1. (2119 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1091 aa)
ANXA1Annexin. (345 aa)
MMRN2Multimerin 2. (925 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
THBS1Thrombospondin 1. (1170 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
STARD13StAR related lipid transfer domain containing 13. (1124 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
FBXW9F-box and WD repeat domain containing 9. (459 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
FBXW7F-box and WD repeat domain containing 7. (708 aa)
RHOJRas homolog family member J. (282 aa)
FGFBP1Fibroblast growth factor binding protein 1. (253 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
PDCD10Programmed cell death 10. (212 aa)
JCADJunctional cadherin 5 associated. (1360 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
CIB1Calcium and integrin binding 1. (187 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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