STRINGSTRING
ABL1 ABL1 VEGFA VEGFA MAP3K3 MAP3K3 CIB1 CIB1 JCAD JCAD FGF2 FGF2 FGFBP1 FGFBP1 HDAC7 HDAC7 SRPX2 SRPX2 KDR KDR RHOJ RHOJ ANXA1 ANXA1 HMOX1 HMOX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABL1Tyrosine-protein kinase. (1150 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
CIB1Calcium and integrin binding 1. (187 aa)
JCADJunctional cadherin 5 associated. (1360 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGFBP1Fibroblast growth factor binding protein 1. (253 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
RHOJRas homolog family member J. (282 aa)
ANXA1Annexin. (345 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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