Your Input: | |
| | TPBGL | Trophoblast glycoprotein like. (370 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (771 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2580 aa) |
| | CTNND1 | Catenin delta 1. (967 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (832 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1084 aa) |
| | AMER2 | APC membrane recruitment protein 2. (640 aa) |
| | TMEM170B | Transmembrane protein 170B. (99 aa) |
| | GLI1 | GLI family zinc finger 1. (1105 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (514 aa) |
| | M3XSG3_MUSPF | CTNNB1_binding domain-containing protein. (169 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (233 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (425 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (500 aa) |
| | M3XW71_MUSPF | Uncharacterized protein. (704 aa) |
| | AMFR | Autocrine motility factor receptor. (548 aa) |
| | M3XZQ7_MUSPF | Ubiquitin-like domain-containing protein. (311 aa) |
| | M3XZR5_MUSPF | RBR-type E3 ubiquitin transferase. (115 aa) |
| | TNN | Tenascin N. (1472 aa) |
| | LRP4 | LDL receptor related protein 4. (1896 aa) |
| | M3Y1K7_MUSPF | Uncharacterized protein. (241 aa) |
| | TMEM131L | Transmembrane 131 like. (1460 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (294 aa) |
| | M3Y377_MUSPF | NTR domain-containing protein. (233 aa) |
| | M3Y3V7_MUSPF | Uncharacterized protein. (160 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (759 aa) |
| | FERMT1 | Fermitin family member 1. (678 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | SHISA3 | Shisa family member 3. (238 aa) |
| | INVS | Inversin. (1079 aa) |
| | NPHP4 | Nephrocystin 4. (1246 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | DAB2IP | DAB2 interacting protein. (1112 aa) |
| | M3Y830_MUSPF | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (2030 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2481 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (443 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (727 aa) |
| | EMD | Emerin. (260 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | SOST | Sclerostin. (213 aa) |
| | NPHP3 | TPR_REGION domain-containing protein. (1331 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | FOXO3 | Forkhead box O3. (671 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | M3YG91_MUSPF | Uncharacterized protein. (88 aa) |
| | BICC1 | BicC family RNA binding protein 1. (849 aa) |
| | SOX17 | SRY-box transcription factor 17. (406 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (434 aa) |
| | NOTCH1 | Notch receptor 1. (2119 aa) |
| | UBAC2 | UBA domain containing 2. (344 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1212 aa) |
| | SCYL2 | SCY1 like pseudokinase 2. (929 aa) |
| | SOX13 | SRY-box transcription factor 13. (615 aa) |
| | RBMS3 | RNA binding motif single stranded interacting protein 3. (436 aa) |
| | FRMD8 | FERM domain containing 8. (465 aa) |
| | M3YM12_MUSPF | Uncharacterized protein. (76 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1265 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (711 aa) |
| | APC | APC regulator of WNT signaling pathway. (2862 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (221 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (827 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) |
| | M3YMX3_MUSPF | Uncharacterized protein. (383 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (348 aa) |
| | SOX10 | SRY-box transcription factor 10. (602 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (127 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (444 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (465 aa) |
| | OTUD5 | OTU deubiquitinase 5. (566 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (209 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa) |
| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa) |
| | SOX9 | SRY-box transcription factor 9. (522 aa) |
| | M3YSA2_MUSPF | Uncharacterized protein. (301 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | AXIN2 | Axin 2. (842 aa) |
| | DAB2 | Disabled-like protein 2, mitogen-responsive phosphoprotein. (769 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (282 aa) |
| | STK3 | Serine/threonine kinase 3. (418 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1436 aa) |
| | AXIN1 | Axin 1. (862 aa) |
| | TLE7 | TLE family member 7. (317 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (348 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (670 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (270 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (317 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (769 aa) |
| | JADE1 | Jade family PHD finger 1. (842 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1127 aa) |
| | GLI3 | GLI family zinc finger 3. (1585 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1134 aa) |
| | M3Z4Q7_MUSPF | Uncharacterized protein. (154 aa) |
| | TPBG | Trophoblast glycoprotein. (419 aa) |
