STRINGSTRING
ACVR1C ACVR1C KLF7 KLF7 PTPN11 PTPN11 SIRT4 SIRT4 CHGA CHGA M3XZQ7_MUSPF M3XZQ7_MUSPF M3XZR5_MUSPF M3XZR5_MUSPF REST REST CRHBP CRHBP M3Y377_MUSPF M3Y377_MUSPF M3Y3R5_MUSPF M3Y3R5_MUSPF ADRA2A ADRA2A M3YA21_MUSPF M3YA21_MUSPF MIDN MIDN M3YEF8_MUSPF M3YEF8_MUSPF PFKL PFKL M3YLM3_MUSPF M3YLM3_MUSPF FKBP1B FKBP1B FAM3D FAM3D FFAR4 FFAR4 KCNB1 KCNB1 KCNJ11 KCNJ11 INHBB INHBB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
KLF7Kruppel like factor 7. (302 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
CHGAChromogranin A. (448 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
RESTRE1 silencing transcription factor. (1098 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
M3Y3R5_MUSPFUncharacterized protein. (137 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (323 aa)
M3YA21_MUSPFWD_REPEATS_REGION domain-containing protein. (467 aa)
MIDNMidnolin. (460 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
M3YLM3_MUSPFV-SNARE coiled-coil homology domain-containing protein. (496 aa)
FKBP1BPeptidylprolyl isomerase. (209 aa)
FAM3DFamily with sequence similarity 3 member D. (223 aa)
FFAR4Free fatty acid receptor 4. (361 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
INHBBInhibin subunit beta B. (238 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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