STRINGSTRING
PNPT1 PNPT1 CNOT7 CNOT7 CNOT2 CNOT2 EXOSC9 EXOSC9 PDE12 PDE12 EXOSC10 EXOSC10 NOCT NOCT ISG20 ISG20 EXOSC7 EXOSC7 ZC3H12A ZC3H12A PARN PARN ERI2 ERI2 CNOT8 CNOT8 ERI3 ERI3 ANGEL2 ANGEL2 CPSF3 CPSF3 TOE1 TOE1 DCP2 DCP2 EXOSC2 EXOSC2 XRN1 XRN1 ERI1 ERI1 DIS3 DIS3 ANGEL1 ANGEL1 EXOSC3 EXOSC3 PAN3 PAN3 PNLDC1 PNLDC1 DIS3L2 DIS3L2 CNOT1 CNOT1 USB1 USB1 TRIR TRIR ISG20L2 ISG20L2 REXO2 REXO2 CNOT6L CNOT6L LRRC27 LRRC27 EXOSC8 EXOSC8 PAN2 PAN2 XRN2 XRN2 CNOT6 CNOT6 DIS3L DIS3L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPT1Polyribonucleotide nucleotidyltransferase 1. (786 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
EXOSC9Exosome component 9. (439 aa)
PDE12Phosphodiesterase 12. (609 aa)
EXOSC10Exosome component 10. (908 aa)
NOCTNocturnin. (365 aa)
ISG20Interferon stimulated exonuclease gene 20. (171 aa)
EXOSC7Exosome component 7. (321 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
PARNPoly(A)-specific ribonuclease. (638 aa)
ERI2ERI1 exoribonuclease family member 2. (678 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
ERI3ERI1 exoribonuclease family member 3. (252 aa)
ANGEL2Angel homolog 2. (544 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (684 aa)
TOE1Target of EGR1, exonuclease. (512 aa)
DCP2Decapping mRNA 2. (422 aa)
EXOSC2Exosome component 2. (293 aa)
XRN15'-3' exoribonuclease 1. (1706 aa)
ERI1Exoribonuclease 1. (349 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
ANGEL1Angel homolog 1. (680 aa)
EXOSC3Exosome component 3. (276 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (854 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (884 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2376 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (280 aa)
TRIRTelomerase RNA component interacting RNase. (176 aa)
ISG20L2Interferon stimulated exonuclease gene 20 like 2. (344 aa)
REXO2RNA exonuclease 2. (237 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (524 aa)
LRRC27Leucine rich repeat containing 27. (558 aa)
EXOSC8Exosome component 8. (276 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1039 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (580 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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