STRINGSTRING
PKP2 PKP2 NPS NPS TRPM4 TRPM4 DLG1 DLG1 SLC8A2 SLC8A2 GBA GBA RNF207 RNF207 CAV1 CAV1 TMEM161B TMEM161B RANGRF RANGRF DLG2 DLG2 FLNA FLNA JUP JUP M3YI89_MUSPF M3YI89_MUSPF FMR1 FMR1 M3YKJ5_MUSPF M3YKJ5_MUSPF RYR2 RYR2 TMEM130 TMEM130 CAV3 CAV3 PAWR PAWR KCNB1 KCNB1 GJA5 GJA5 M3Z6U8_MUSPF M3Z6U8_MUSPF KCNE3 KCNE3 KCNJ2 KCNJ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKP2Plakophilin 2. (836 aa)
NPSNeuropeptide S. (68 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1211 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
GBAGlucosylceramidase. (547 aa)
RNF207Ring finger protein 207. (639 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
TMEM161BTransmembrane protein 161B. (487 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
DLG2Uncharacterized protein. (833 aa)
FLNAFilamin A. (2647 aa)
JUPJunction plakoglobin. (744 aa)
M3YI89_MUSPFUncharacterized protein. (271 aa)
FMR1Fragile X mental retardation 1. (615 aa)
M3YKJ5_MUSPFUncharacterized protein. (247 aa)
RYR2Ryanodine receptor 2. (4966 aa)
TMEM130Transmembrane protein 130. (423 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PAWRPro-apoptotic WT1 regulator. (360 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
M3Z6U8_MUSPFSmall ubiquitin-related modifier. (100 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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