STRINGSTRING
RNF112 RNF112 P2RX3 P2RX3 GAP43 GAP43 ALS2 ALS2 BMPR2 BMPR2 PKP4 PKP4 DNAJC6 DNAJC6 M3XNV3_MUSPF M3XNV3_MUSPF M3XNV5_MUSPF M3XNV5_MUSPF PDE4B PDE4B RAPGEF4 RAPGEF4 LRRC7 LRRC7 SYNDIG1 SYNDIG1 ADCY8 ADCY8 PPP1R9A PPP1R9A SHANK1 SHANK1 LRFN5 LRFN5 GRIK2 GRIK2 LRRC4B LRRC4B DCLK1 DCLK1 SHANK3 SHANK3 LOC101681822 LOC101681822 MAPK8IP2 MAPK8IP2 ADD3 ADD3 GRID2 GRID2 NTRK2 NTRK2 FXR1 FXR1 SYNGAP1 SYNGAP1 INSYN2A INSYN2A BCR BCR RS1 RS1 NETO2 NETO2 EIF3A EIF3A M3XVU1_MUSPF M3XVU1_MUSPF LIN7B LIN7B LRFN4 LRFN4 SYT12 SYT12 ARHGAP44 ARHGAP44 SHISA6 SHISA6 DLG5 DLG5 PAK2 PAK2 FBXO45 FBXO45 DMTN DMTN DGCR8 DGCR8 PAK3 PAK3 GRIN2D GRIN2D SIGMAR1 SIGMAR1 BACE1 BACE1 ADAM10 ADAM10 SLC8A2 SLC8A2 KPNA1 KPNA1 SHANK2 SHANK2 LIN7A LIN7A HOMER1 HOMER1 CLSTN2 CLSTN2 CAP2 CAP2 SYT11 SYT11 DTNBP1 DTNBP1 M3Y2F6_MUSPF M3Y2F6_MUSPF GRIK4 GRIK4 M3Y3A6_MUSPF M3Y3A6_MUSPF CLSTN1 CLSTN1 PLCB4 PLCB4 LRRC4 LRRC4 ADD2 ADD2 SHISA7 SHISA7 ABHD17A ABHD17A SYNJ2BP SYNJ2BP USP50 USP50 USP8 USP8 ERBB4 ERBB4 SCRIB SCRIB CDK5 CDK5 GRID1 GRID1 M3YBA2_MUSPF M3YBA2_MUSPF LZTS3 LZTS3 ABHD17B ABHD17B EFNB3 EFNB3 ATP1B2 ATP1B2 FXR2 FXR2 RPS3 RPS3 PALM PALM SLC30A3 SLC30A3 MPP2 MPP2 ADGRA1 ADGRA1 TMEM108 TMEM108 ARHGEF9 ARHGEF9 CACNG7 CACNG7 CACNG8 CACNG8 PRRT1 PRRT1 GRM5 GRM5 SYT9 SYT9 SORCS2 SORCS2 DCC DCC RTN4 RTN4 DLG4 DLG4 ADD1 ADD1 CALB1 CALB1 LOC106004699 LOC106004699 M3YIE9_MUSPF M3YIE9_MUSPF LIN7C LIN7C M3YIF4_MUSPF M3YIF4_MUSPF SEMA4C SEMA4C PLEKHA5 PLEKHA5 FMR1 FMR1 EPS8 EPS8 PTPRO PTPRO GRIN2B GRIN2B DBN1 DBN1 RGS14 RGS14 CACNG3 CACNG3 TSC1 TSC1 CACNG2 CACNG2 CPEB4 CPEB4 M3YN49_MUSPF M3YN49_MUSPF M3YNC2_MUSPF M3YNC2_MUSPF PICK1 PICK1 M3YPJ9_MUSPF M3YPJ9_MUSPF GRIA1 GRIA1 LRFN2 LRFN2 GNG3 GNG3 SYNPO SYNPO BSN BSN GRIN2C GRIN2C DAGLA DAGLA DVL1 DVL1 MAP1B MAP1B SHISA9 SHISA9 RGS9 RGS9 AKAP7 AKAP7 CACNG5 CACNG5 CACNG4 CACNG4 GRIN2A GRIN2A RGS7BP RGS7BP GRIN1 GRIN1 SRCIN1 SRCIN1 RNF19A RNF19A DROSHA DROSHA PDPK1 PDPK1 NGFR NGFR SAMD14 SAMD14 PPP1R9B PPP1R9B ABHD17C ABHD17C M3YVL3_MUSPF M3YVL3_MUSPF TSC2 TSC2 HOMER2 HOMER2 G9KNR6_MUSPF G9KNR6_MUSPF NETO1 NETO1 CLSTN3 CLSTN3 SORCS3 SORCS3 EEF2K EEF2K NEURL1 NEURL1 PSD PSD ITPR1 ITPR1 CAMK1 CAMK1 ATP2B2 ATP2B2 NPTN NPTN INSYN1 INSYN1 LRFN1 LRFN1 GRM1 GRM1 STXBP5 STXBP5 ADCY1 ADCY1 DBNL DBNL PCLO PCLO GRM3 GRM3 ADAM22 ADAM22 NRGN NRGN LRRC4C LRRC4C SLITRK1 SLITRK1 GPER1 GPER1 M3Z5Z4_MUSPF M3Z5Z4_MUSPF M3Z655_MUSPF M3Z655_MUSPF SLITRK3 SLITRK3 M3Z6E6_MUSPF M3Z6E6_MUSPF AKAP5 AKAP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF112Ring finger protein 112. (605 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
GAP43Growth associated protein 43. (242 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1657 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
PKP4Plakophilin 4. (1193 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (944 aa)
M3XNV3_MUSPFUncharacterized protein. (93 aa)
M3XNV5_MUSPFPDE4_UCR domain-containing protein. (232 aa)
PDE4BPhosphodiesterase. (544 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
LRRC7Leucine rich repeat containing 7. (1528 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1312 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1954 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (719 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (844 aa)
LRRC4BLeucine rich repeat containing 4B. (478 aa)
DCLK1Doublecortin like kinase 1. (751 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1712 aa)
LOC101681822SAM domain-containing protein. (1250 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (832 aa)
ADD3Adducin 3. (706 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (922 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1205 aa)
INSYN2AInhibitory synaptic factor 2A. (480 aa)
BCRBCR activator of RhoGEF and GTPase. (1279 aa)
RS1Retinoschisin 1. (224 aa)
NETO2Neuropilin and tolloid like 2. (525 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1348 aa)
M3XVU1_MUSPFUncharacterized protein. (227 aa)
LIN7BLin-7 homolog B, crumbs cell polarity complex component. (303 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (636 aa)
SYT12Synaptotagmin 12. (421 aa)
ARHGAP44Rho GTPase activating protein 44. (759 aa)
SHISA6Shisa family member 6. (317 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
FBXO45F-box protein 45. (283 aa)
DMTNDematin actin binding protein. (350 aa)
DGCR8DGCR8 microprocessor complex subunit. (754 aa)
PAK3P21 (RAC1) activated kinase 3. (583 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (738 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (505 aa)
ADAM10ADAM metallopeptidase domain 10. (737 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1513 aa)
LIN7ALin-7 homolog A, crumbs cell polarity complex component. (172 aa)
HOMER1Homer scaffold protein 1. (354 aa)
CLSTN2Calsyntenin 2. (898 aa)
CAP2Adenylyl cyclase-associated protein; Belongs to the CAP family. (390 aa)
SYT11Synaptotagmin 11. (431 aa)
DTNBP1Dystrobrevin binding protein 1. (349 aa)
M3Y2F6_MUSPFUncharacterized protein. (181 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
M3Y3A6_MUSPFUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (853 aa)
CLSTN1Calsyntenin 1. (943 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LRRC4Leucine rich repeat containing 4. (632 aa)
ADD2Adducin 2. (723 aa)
SHISA7Shisa family member 7. (564 aa)
ABHD17AAbhydrolase domain containing 17A. (314 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (376 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1116 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
SCRIBScribble planar cell polarity protein. (1523 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (777 aa)
M3YBA2_MUSPFANF_receptor domain-containing protein. (347 aa)
LZTS3Leucine zipper tumor suppressor family member 3. (673 aa)
ABHD17BAbhydrolase domain containing 17B. (296 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
FXR2FMR1 autosomal homolog 2. (703 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
PALMParalemmin. (378 aa)
SLC30A3Solute carrier family 30 member 3. (388 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (585 aa)
ADGRA1Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. (570 aa)
TMEM108Transmembrane protein 108. (532 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (562 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (297 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
GRM5Glutamate metabotropic receptor 5. (987 aa)
SYT9Synaptotagmin 9. (491 aa)
SORCS2Sortilin related VPS10 domain containing receptor 2. (987 aa)
DCCDCC netrin 1 receptor. (1168 aa)
RTN4Reticulon. (986 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
ADD1Adducin 1. (775 aa)
CALB1Calbindin 1. (261 aa)
LOC106004699Uncharacterized protein. (178 aa)
M3YIE9_MUSPFUncharacterized protein. (230 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
M3YIF4_MUSPFUncharacterized protein. (817 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (867 aa)
PLEKHA5Pleckstrin homology domain containing A5. (1169 aa)
FMR1Fragile X mental retardation 1. (615 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (821 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1212 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1550 aa)
DBN1Drebrin 1. (656 aa)
RGS14Regulator of G protein signaling 14. (568 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
TSC1TSC complex subunit 1. (1165 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (729 aa)
M3YN49_MUSPFUncharacterized protein. (176 aa)
M3YNC2_MUSPFUncharacterized protein. (177 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
M3YPJ9_MUSPFReticulon. (240 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (494 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
SYNPOSynaptopodin. (1040 aa)
BSNBassoon presynaptic cytomatrix protein. (3838 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1109 aa)
DAGLADiacylglycerol lipase alpha. (1048 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
MAP1BMicrotubule associated protein 1B. (2471 aa)
SHISA9Shisa family member 9. (344 aa)
RGS9Regulator of G protein signaling 9. (675 aa)
AKAP7A-kinase anchoring protein 7. (317 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (318 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1307 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (257 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1328 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
DROSHADrosha ribonuclease III. (1374 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
NGFRNerve growth factor receptor. (429 aa)
SAMD14Sterile alpha motif domain containing 14. (424 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (820 aa)
ABHD17CAbhydrolase domain containing 17C. (240 aa)
M3YVL3_MUSPFWH1 domain-containing protein. (358 aa)
TSC2TSC complex subunit 2. (1906 aa)
HOMER2Homer scaffold protein 2. (386 aa)
G9KNR6_MUSPFShisa-like protein 8. (163 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
CLSTN3Calsyntenin 3. (957 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1224 aa)
EEF2KEukaryotic elongation factor 2 kinase. (724 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
PSDPleckstrin and Sec7 domain containing. (1027 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (409 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1199 aa)
NPTNNeuroplastin. (398 aa)
INSYN1Inhibitory synaptic factor 1. (292 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (770 aa)
GRM1Glutamate metabotropic receptor 1. (906 aa)
STXBP5Syntaxin binding protein 5. (997 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
DBNLDrebrin like. (432 aa)
PCLOPiccolo presynaptic cytomatrix protein. (4560 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
ADAM22ADAM metallopeptidase domain 22. (943 aa)
NRGNNeurogranin. (78 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
M3Z5Z4_MUSPFFABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
M3Z655_MUSPFFABP domain-containing protein. (134 aa)
SLITRK3SLIT and NTRK like family member 3. (978 aa)
M3Z6E6_MUSPFUncharacterized protein. (134 aa)
AKAP5A-kinase anchoring protein 5. (429 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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