(18 nodes) Regulation of phospholipase C activity network (Mustela putorius)

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Your Input:
	ARHGAP6	Rho GTPase activating protein 6. (810 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (470 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	PHB2	Prohibitin. (299 aa)
	PHB	Prohibitin. (272 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1137 aa)
	ITK	Tyrosine-protein kinase. (620 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	AVPR1B	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (283 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	ABL2	Tyrosine-protein kinase. (1079 aa)
	NMUR1	Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (481 aa)
	FLT1	Receptor protein-tyrosine kinase. (1338 aa)
	GPR55	G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (329 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSMPUP00000012584	ENSMPUP00000005172	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.929
ABL2	ABL1	ENSMPUP00000005172	ENSMPUP00000012584	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.929
ESR1	FGF2	ENSMPUP00000010404	ENSMPUP00000017277	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.427
ESR1	PHB	ENSMPUP00000010404	ENSMPUP00000015271	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Prohibitin.	0.412
ESR1	PHB2	ENSMPUP00000010404	ENSMPUP00000016660	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Prohibitin.	0.735
ESR1	PTH	ENSMPUP00000010404	ENSMPUP00000013054	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.416
FGF2	ESR1	ENSMPUP00000017277	ENSMPUP00000010404	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.427
FGF2	FLT1	ENSMPUP00000017277	ENSMPUP00000004662	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein-tyrosine kinase.	0.928
FGF2	PDGFRA	ENSMPUP00000017277	ENSMPUP00000005771	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.963
FGF2	PDGFRB	ENSMPUP00000017277	ENSMPUP00000013885	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.935
FLT1	FGF2	ENSMPUP00000004662	ENSMPUP00000017277	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.928
FLT1	PDGFRB	ENSMPUP00000004662	ENSMPUP00000013885	Receptor protein-tyrosine kinase.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.588
GPR55	LPAR1	ENSMPUP00000004616	ENSMPUP00000007536	G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.546
HTR2A	HTR2B	ENSMPUP00000001479	ENSMPUP00000004664	5-hydroxytryptamine receptor 2A.	5-hydroxytryptamine receptor 2B.	0.968
HTR2B	HTR2A	ENSMPUP00000004664	ENSMPUP00000001479	5-hydroxytryptamine receptor 2B.	5-hydroxytryptamine receptor 2A.	0.968
LPAR1	GPR55	ENSMPUP00000007536	ENSMPUP00000004616	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family.	0.546
PDGFRA	FGF2	ENSMPUP00000005771	ENSMPUP00000017277	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.963
PDGFRA	PDGFRB	ENSMPUP00000005771	ENSMPUP00000013885	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.966
PDGFRB	FGF2	ENSMPUP00000013885	ENSMPUP00000017277	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.935
PDGFRB	FLT1	ENSMPUP00000013885	ENSMPUP00000004662	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	Receptor protein-tyrosine kinase.	0.588