(15 nodes) Regulation of mitochondrial membrane permeability involved in apoptotic process network (Mustela putorius)

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Your Input:
	M3Y0R3_MUSPF	Uncharacterized protein. (201 aa)
	M3XND5_MUSPF	Uncharacterized protein. (207 aa)
	M3XP25_MUSPF	Uncharacterized protein. (219 aa)
	BNIP3	BCL2 interacting protein 3. (190 aa)
	VDAC2	Voltage dependent anion channel 2. (294 aa)
	NOL3	Nucleolar protein 3. (217 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
	BCL2L11	BCL2 like 11. (232 aa)
	NAIF1	Nuclear apoptosis inducing factor 1. (327 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (686 aa)
	STPG1	Sperm tail PG-rich repeat containing 1. (335 aa)
	RHOT2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (620 aa)
	EYA2	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (533 aa)
	M3XWP6_MUSPF	Uncharacterized protein. (120 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L11	M3Y0R3_MUSPF	ENSMPUP00000009390	ENSMPUP00000004914	BCL2 like 11.	Uncharacterized protein.	0.958
BNIP3	M3XND5_MUSPF	ENSMPUP00000002297	ENSMPUP00000000585	BCL2 interacting protein 3.	Uncharacterized protein.	0.641
BNIP3	M3XP25_MUSPF	ENSMPUP00000002297	ENSMPUP00000000825	BCL2 interacting protein 3.	Uncharacterized protein.	0.640
BNIP3	TP53	ENSMPUP00000002297	ENSMPUP00000008945	BCL2 interacting protein 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.507
M3XND5_MUSPF	BNIP3	ENSMPUP00000000585	ENSMPUP00000002297	Uncharacterized protein.	BCL2 interacting protein 3.	0.641
M3XP25_MUSPF	BNIP3	ENSMPUP00000000825	ENSMPUP00000002297	Uncharacterized protein.	BCL2 interacting protein 3.	0.640
M3Y0R3_MUSPF	BCL2L11	ENSMPUP00000004914	ENSMPUP00000009390	Uncharacterized protein.	BCL2 like 11.	0.958
M3Y0R3_MUSPF	TP53	ENSMPUP00000004914	ENSMPUP00000008945	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.653
RHOT1	RHOT2	ENSMPUP00000014594	ENSMPUP00000015880	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.853
RHOT1	VDAC2	ENSMPUP00000014594	ENSMPUP00000003236	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Voltage dependent anion channel 2.	0.440
RHOT2	RHOT1	ENSMPUP00000015880	ENSMPUP00000014594	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.853
RHOT2	VDAC2	ENSMPUP00000015880	ENSMPUP00000003236	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Voltage dependent anion channel 2.	0.633
TP53	BNIP3	ENSMPUP00000008945	ENSMPUP00000002297	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BCL2 interacting protein 3.	0.507
TP53	M3Y0R3_MUSPF	ENSMPUP00000008945	ENSMPUP00000004914	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Uncharacterized protein.	0.653
VDAC2	RHOT1	ENSMPUP00000003236	ENSMPUP00000014594	Voltage dependent anion channel 2.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.440
VDAC2	RHOT2	ENSMPUP00000003236	ENSMPUP00000015880	Voltage dependent anion channel 2.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.633