STRINGSTRING
M3YCX9_MUSPF M3YCX9_MUSPF EGFR EGFR M3YT25_MUSPF M3YT25_MUSPF RIPK1 RIPK1 M3XVG1_MUSPF M3XVG1_MUSPF TRUB1 TRUB1 BMP4 BMP4 TP53 TP53 IL6 IL6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3YCX9_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (671 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
M3YT25_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (372 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
M3XVG1_MUSPFHelicase C-terminal domain-containing protein. (106 aa)
TRUB1TruB pseudouridine synthase family member 1. (350 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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