(10 nodes) Regulation of chemokine (C-X-C motif) ligand 2 production network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
	FOXP1	Forkhead box P1. (676 aa)
	M3YUJ9_MUSPF	HMG box domain-containing protein. (171 aa)
	CD74	CD74 molecule. (279 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	TIRAP	TIR domain containing adaptor protein. (227 aa)
	F2RL1	F2R like trypsin receptor 1. (397 aa)
	M3XZP3_MUSPF	HMG box domain-containing protein. (215 aa)
	M3XM17_MUSPF	Uncharacterized protein. (208 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
M3XM17_MUSPF	MYD88	ENSMPUP00000000117	ENSMPUP00000002726	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.498
M3XM17_MUSPF	TLR4	ENSMPUP00000000117	ENSMPUP00000001697	Uncharacterized protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.803
M3XM17_MUSPF	TNF	ENSMPUP00000000117	ENSMPUP00000011297	Uncharacterized protein.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.469
M3XZP3_MUSPF	MYD88	ENSMPUP00000004544	ENSMPUP00000002726	HMG box domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.498
M3XZP3_MUSPF	TLR4	ENSMPUP00000004544	ENSMPUP00000001697	HMG box domain-containing protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.803
M3XZP3_MUSPF	TNF	ENSMPUP00000004544	ENSMPUP00000011297	HMG box domain-containing protein.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.469
M3YUJ9_MUSPF	MYD88	ENSMPUP00000015009	ENSMPUP00000002726	HMG box domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.498
M3YUJ9_MUSPF	TLR4	ENSMPUP00000015009	ENSMPUP00000001697	HMG box domain-containing protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.803
M3YUJ9_MUSPF	TNF	ENSMPUP00000015009	ENSMPUP00000011297	HMG box domain-containing protein.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.469
MYD88	M3XM17_MUSPF	ENSMPUP00000002726	ENSMPUP00000000117	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.498
MYD88	M3XZP3_MUSPF	ENSMPUP00000002726	ENSMPUP00000004544	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	HMG box domain-containing protein.	0.498
MYD88	M3YUJ9_MUSPF	ENSMPUP00000002726	ENSMPUP00000015009	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	HMG box domain-containing protein.	0.498
MYD88	TIRAP	ENSMPUP00000002726	ENSMPUP00000006591	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain containing adaptor protein.	0.996
MYD88	TLR4	ENSMPUP00000002726	ENSMPUP00000001697	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.999
MYD88	TNF	ENSMPUP00000002726	ENSMPUP00000011297	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.743
TIRAP	MYD88	ENSMPUP00000006591	ENSMPUP00000002726	TIR domain containing adaptor protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.996
TIRAP	TLR4	ENSMPUP00000006591	ENSMPUP00000001697	TIR domain containing adaptor protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.995
TIRAP	TNF	ENSMPUP00000006591	ENSMPUP00000011297	TIR domain containing adaptor protein.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.483
TLR4	M3XM17_MUSPF	ENSMPUP00000001697	ENSMPUP00000000117	Toll like receptor 4; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.803
TLR4	M3XZP3_MUSPF	ENSMPUP00000001697	ENSMPUP00000004544	Toll like receptor 4; Belongs to the Toll-like receptor family.	HMG box domain-containing protein.	0.803