STRINGSTRING
F2 F2 F2RL1 F2RL1 CLEC7A CLEC7A PARK7 PARK7 M3Y653_MUSPF M3Y653_MUSPF MMP8 MMP8 RNF41 RNF41 CLCN3 CLCN3 CYBA CYBA THBS1 THBS1 TP53 TP53 TGFB3 TGFB3 PLCG2 PLCG2 DUOXA2 DUOXA2 DUOXA1 DUOXA1 PDGFB PDGFB GRB2 GRB2 M3YRV1_MUSPF M3YRV1_MUSPF CDKN1A CDKN1A ZC3H12A ZC3H12A ZNF205 ZNF205 TSPO TSPO PRKCD PRKCD TLR4 TLR4 TGFB1 TGFB1 ROMO1 ROMO1 RAB27A RAB27A PID1 PID1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (602 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
CLEC7AC-type lectin domain containing 7A. (248 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
M3Y653_MUSPFProtein kinase domain-containing protein. (212 aa)
MMP8Matrix metallopeptidase 8. (473 aa)
RNF41Ring finger protein 41. (317 aa)
CLCN3Chloride channel protein. (818 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
THBS1Thrombospondin 1. (1170 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
DUOXA2Dual oxidase maturation factor 2. (325 aa)
DUOXA1Dual oxidase maturation factor 1. (430 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
M3YRV1_MUSPFUncharacterized protein. (286 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
ZNF205Zinc finger protein 205. (546 aa)
TSPOTranslocator protein. (169 aa)
PRKCDProtein kinase C. (730 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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