STRINGSTRING
TGFB3 TGFB3 PAX6 PAX6 TRAF6 TRAF6 IGF1 IGF1 NIBAN2 NIBAN2 GATA3 GATA3 EP300 EP300 IFNG IFNG TGFB1 TGFB1 RB1 RB1 HAND2 HAND2 GTF2B GTF2B PARK7 PARK7 DDRGK1 DDRGK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
PAX6Paired box 6. (436 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
IGF1Insulin like growth factor 1. (153 aa)
NIBAN2Niban apoptosis regulator 2. (733 aa)
GATA3GATA binding protein 3. (444 aa)
EP300E1A binding protein p300. (2425 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
RB1RB transcriptional corepressor 1. (948 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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