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| | SIRT1 | Sirtuin 1. (557 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (587 aa) |
| | UIMC1 | Ubiquitin interaction motif containing 1. (644 aa) |
| | M3YLL3_MUSPF | SET domain-containing protein. (374 aa) |
| | M3YLM2_MUSPF | Uncharacterized protein. (77 aa) |
| | INO80E | INO80 complex subunit E. (244 aa) |
| | PPP4C | Protein phosphatase 4 catalytic subunit. (271 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (283 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1361 aa) |
| | ENDOG | Endonuclease. (237 aa) |
| | EPC1 | Enhancer of polycomb homolog. (813 aa) |
| | OTUB1 | Ubiquitin thioesterase. (271 aa) |
| | SMG1 | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3658 aa) |
| | THOC5 | THO complex 5. (683 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (449 aa) |
| | M3YPV3_MUSPF | Uncharacterized protein. (405 aa) |
| | CCDC117 | Coiled-coil domain containing 117. (277 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (468 aa) |
| | WAS | WASP actin nucleation promoting factor. (501 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | CD74 | CD74 molecule. (279 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (986 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa) |
| | FBXO4 | F-box protein 4. (387 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) |
| | MCRS1 | Microspherule protein 1. (462 aa) |
| | M3YT25_MUSPF | Uncharacterized protein; Belongs to the DEAD box helicase family. (372 aa) |
| | AXIN2 | Axin 2. (842 aa) |
| | ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (360 aa) |
| | HELQ | Helicase, POLQ like. (961 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1892 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (171 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (639 aa) |
| | BCLAF1 | BCL2 associated transcription factor 1. (921 aa) |
| | M3YU40_MUSPF | Uncharacterized protein. (158 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2564 aa) |
| | M3YUJ9_MUSPF | HMG box domain-containing protein. (171 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2544 aa) |
| | M3YUX6_MUSPF | Uncharacterized protein. (497 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (583 aa) |
| | TMEM161A | Transmembrane protein 161A. (480 aa) |
| | EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa) |
| | MBTD1 | Mbt domain containing 1. (628 aa) |
| | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (624 aa) |
| | AUNIP | Aurora kinase A and ninein interacting protein. (353 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (679 aa) |
| | BABAM1 | BRISC and BRCA1 A complex member 1. (336 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (156 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (874 aa) |
| | BRCC3 | BRCA1/BRCA2-containing complex subunit 3. (316 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) |
| | FBH1 | F-box DNA helicase 1. (1045 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | M3YZ44_MUSPF | TCTP domain-containing protein; Belongs to the TCTP family. (161 aa) |
| | NEK4 | NIMA related kinase 4. (787 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | ING4 | Inhibitor of growth family member 4. (239 aa) |
| | SLF2 | SMC5-SMC6 complex localization factor 2. (1173 aa) |
| | PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (412 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1029 aa) |
| | SKIL | SKI like proto-oncogene. (664 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (345 aa) |
| | ANKRD1 | Ankyrin repeat domain 1. (319 aa) |
| | PML | Promyelocytic leukemia. (876 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) |
| | HELB | DNA helicase B. (1080 aa) |
| | M3Z1E7_MUSPF | Uncharacterized protein. (109 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (533 aa) |
| | BABAM2 | BRISC and BRCA1 A complex member 2. (383 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (416 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1207 aa) |
| | FIGNL1 | Fidgetin like 1; Belongs to the AAA ATPase family. (681 aa) |
| | M3Z445_MUSPF | TCTP domain-containing protein; Belongs to the TCTP family. (167 aa) |
| | TRIM32 | Tripartite motif containing 32. (673 aa) |
| | MAGEF1 | MAGE family member F1. (326 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (146 aa) |
| | MORF4L2 | Mortality factor 4 like 2. (288 aa) |
| | HIC1 | HIC ZBTB transcriptional repressor 1. (713 aa) |
| | COPS3 | COP9 signalosome subunit 3. (457 aa) |
| | M3XLY5_MUSPF | TCTP domain-containing protein; Belongs to the TCTP family. (171 aa) |
| | KLHL15 | Kelch like family member 15. (602 aa) |
| | M3XM17_MUSPF | Uncharacterized protein. (208 aa) |
| | FEM1B | Fem-1 homolog B. (627 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2475 aa) |
| | ARID2 | AT-rich interaction domain 2. (1777 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (665 aa) |
| | INO80D | INO80 complex subunit D. (1029 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (708 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1494 aa) |
| | M3XND2_MUSPF | GST C-terminal domain-containing protein. (174 aa) |
| | MRNIP | MRN complex interacting protein. (339 aa) |
| | M3XNQ3_MUSPF | DUF4502 domain-containing protein. (379 aa) |
| | M3XP56_MUSPF | Protein kinase domain-containing protein. (158 aa) |
| | M3XP59_MUSPF | SAM domain-containing protein. (355 aa) |
| | CLU | Clusterin; Belongs to the clusterin family. (462 aa) |
| | PBK | PDZ binding kinase. (323 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (145 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4110 aa) |
| | M3XPZ1_MUSPF | DUF4503 domain-containing protein. (370 aa) |
| | MYC | V-myc myelocytomatosis viral oncoprotein-like protein. (453 aa) |
| | M3XQT3_MUSPF | Uncharacterized protein. (1208 aa) |
| | KMT5A | Lysine methyltransferase 5A. (321 aa) |
| | TPT1 | Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (175 aa) |
| | BCL7A | BAF chromatin remodeling complex subunit BCL7A. (201 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (520 aa) |
| | EP400 | E1A binding protein p400. (3107 aa) |
| | HDAC10 | Histone deacetylase 10. (663 aa) |
| | FXR1 | FMR1 autosomal homolog 1. (648 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | BCL2L12 | BCL2 like 12. (332 aa) |
| | WDR48 | WD repeat domain 48. (429 aa) |
| | FANCB | FA complementation group B. (848 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (319 aa) |
| | DDX39A | DExD-box helicase 39A. (427 aa) |
| | M3XVG1_MUSPF | Helicase C-terminal domain-containing protein. (106 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (233 aa) |
| | M3XW93_MUSPF | Uncharacterized protein. (226 aa) |
| | NKX3-1 | NK3 homeobox 1. (231 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (925 aa) |
| | EPC2 | Enhancer of polycomb homolog. (807 aa) |
| | RADX | RPA1 related single stranded DNA binding protein, X-linked. (847 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1414 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (572 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase, 10. (226 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | M3XY50_MUSPF | Uncharacterized protein. (459 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1145 aa) |
| | CYREN | Cell cycle regulator of NHEJ. (155 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2038 aa) |
| | KMT5B | Lysine methyltransferase 5B. (940 aa) |
| | OOEP | Oocyte expressed protein. (149 aa) |
| | M3XZ29_MUSPF | MOEP19 domain-containing protein. (196 aa) |
| | SPIRE1 | Spire type actin nucleation factor 1. (642 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (514 aa) |
| | M3XZP3_MUSPF | HMG box domain-containing protein. (215 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | SIRT6 | Sirtuin 6. (359 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (745 aa) |
| | PARP9 | Poly [ADP-ribose] polymerase. (995 aa) |
| | UBQLN4 | Ubiquilin 4. (591 aa) |
| | SOX4 | SRY-box transcription factor 4. (269 aa) |
| | POLQ | DNA polymerase theta. (2488 aa) |
| | DEK | DEK proto-oncogene. (369 aa) |
| | HDGFL2 | HDGF like 2. (715 aa) |
| | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (2007 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (465 aa) |
| | THOC1 | THO complex 1. (657 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (294 aa) |
| | MUC1 | SEA domain-containing protein. (560 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (897 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa) |
| | CDKN2D | Cyclin-dependent kinase inhibitor 2D. (166 aa) |
| | HSF1 | Heat shock transcription factor 1. (555 aa) |
| | XRCC1 | X-ray repair cross complementing 1. (646 aa) |
| | POT1 | Protection of telomeres 1. (785 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | SPIRE2 | Spire type actin nucleation factor 2. (640 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) |
| | KMT5C | Lysine methyltransferase 5C. (459 aa) |
| | M3Y878_MUSPF | Uncharacterized protein. (67 aa) |
| | USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (785 aa) |
| | MRGBP | MRG domain binding protein. (179 aa) |
| | DDIAS | DNA damage induced apoptosis suppressor. (960 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (443 aa) |
| | TRIM28 | Tripartite motif containing 28. (700 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1282 aa) |
| | M3YBF2_MUSPF | Uncharacterized protein. (61 aa) |
| | INO80 | INO80 complex ATPase subunit. (1561 aa) |
| | SHLD2 | Shieldin complex subunit 2. (906 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (539 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa) |
| | FXR2 | FMR1 autosomal homolog 2. (703 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1482 aa) |
| | M3YCX9_MUSPF | Uncharacterized protein; Belongs to the DEAD box helicase family. (671 aa) |
| | RNF169 | Ring finger protein 169. (607 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | FOXM1 | Forkhead box M1. (760 aa) |
| | PAXIP1 | PAX interacting protein 1. (1293 aa) |
| | PARG | Poly(ADP-ribose) glycohydrolase. (977 aa) |
| | BRD8 | Bromodomain containing 8. (951 aa) |
| | FAM168A | Family with sequence similarity 168 member A. (244 aa) |
| | TERF2IP | TERF2 interacting protein. (401 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (713 aa) |
| | M3YEZ0_MUSPF | RAD51_interact domain-containing protein. (326 aa) |
| | RFWD3 | Ring finger and WD repeat domain 3. (772 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | PRKCG | Non-specific serine/threonine protein kinase. (569 aa) |
| | TTI2 | TELO2 interacting protein 2. (508 aa) |
| | TEX15 | Testis expressed 15, meiosis and synapsis associated. (3190 aa) |
| | PTTG1IP | PTTG1 interacting protein. (182 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1969 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | ARMT1 | Acidic residue methyltransferase 1. (477 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (396 aa) |
| | FBXO5 | F-box protein 5. (386 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa) |
| | WDR76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (629 aa) |
| | ENSMPUP00000010584 | annotation not available (61 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1344 aa) |
| | ZNF365 | Zinc finger protein 365. (407 aa) |
| | FAM178B | Family with sequence similarity 178 member B. (654 aa) |
| | M3YJ04_MUSPF | MRG domain-containing protein. (270 aa) |
| | DDX39B | DExD-box helicase 39B. (428 aa) |
| | M3YJ27_MUSPF | Uncharacterized protein. (524 aa) |
| | FMR1 | Fragile X mental retardation 1. (615 aa) |
| | DHX9 | DExH-box helicase 9. (1200 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | IER3 | Immediate early response 3. (155 aa) |
| | CD44 | CD44 molecule (Indian blood group). (704 aa) |
| | NACC2 | NACC family member 2. (636 aa) |
| | PPP1R10 | Protein phosphatase 1 regulatory subunit 10. (956 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (531 aa) |
| | PARPBP | PARP1 binding protein. (587 aa) |
| | BCL7C | BAF chromatin remodeling complex subunit BCL7C. (217 aa) |
