STRINGSTRING
MORF4L2 MORF4L2 M3XM17_MUSPF M3XM17_MUSPF RIF1 RIF1 ARID2 ARID2 INO80D INO80D PLA2R1 PLA2R1 M3XND2_MUSPF M3XND2_MUSPF MRNIP MRNIP M3XNQ3_MUSPF M3XNQ3_MUSPF M3XP56_MUSPF M3XP56_MUSPF M3XP59_MUSPF M3XP59_MUSPF PBK PBK UBE2V2 UBE2V2 PRKDC PRKDC M3XPZ1_MUSPF M3XPZ1_MUSPF MYC MYC M3XQT3_MUSPF M3XQT3_MUSPF BCL7A BCL7A PNKP PNKP EP400 EP400 HDAC10 HDAC10 FXR1 FXR1 WDR48 WDR48 FANCB FANCB NSMCE4A NSMCE4A M3XVG1_MUSPF M3XVG1_MUSPF RUVBL2 RUVBL2 NKX3-1 NKX3-1 CCAR2 CCAR2 EPC2 EPC2 POGZ POGZ RAD9A RAD9A RNF168 RNF168 VPS72 VPS72 M3XY50_MUSPF M3XY50_MUSPF SLF1 SLF1 KMT5B KMT5B OOEP OOEP M3XZ29_MUSPF M3XZ29_MUSPF SPIRE1 SPIRE1 PIAS4 PIAS4 M3XZP3_MUSPF M3XZP3_MUSPF PARP1 PARP1 UCHL5 UCHL5 SIRT6 SIRT6 DTX3L DTX3L PARP9 PARP9 HDGFL2 HDGFL2 SMCHD1 SMCHD1 RBBP8 RBBP8 ATM ATM PCNA PCNA XRCC1 XRCC1 ING3 ING3 SPIRE2 SPIRE2 ERCC8 ERCC8 KMT5C KMT5C M3Y878_MUSPF M3Y878_MUSPF MRGBP MRGBP SPRED1 SPRED1 TRIM28 TRIM28 NFRKB NFRKB INO80 INO80 SHLD2 SHLD2 WRAP53 WRAP53 FXR2 FXR2 RPS3 RPS3 HIC1 HIC1 ERCC6 ERCC6 M3YCX9_MUSPF M3YCX9_MUSPF TIGAR TIGAR FOXM1 FOXM1 PAXIP1 PAXIP1 BRD8 BRD8 FAM168A FAM168A M3YEZ0_MUSPF M3YEZ0_MUSPF PRKCG PRKCG TTI2 TTI2 TFPT TFPT EYA1 EYA1 FAM178B FAM178B M3YJ04_MUSPF M3YJ04_MUSPF M3YJ27_MUSPF M3YJ27_MUSPF FMR1 FMR1 DHX9 DHX9 KAT5 KAT5 NACC2 NACC2 PARP3 PARP3 SIRT1 SIRT1 BCL7C BCL7C ATR ATR UIMC1 UIMC1 INO80E INO80E NSMCE1 NSMCE1 ENDOG ENDOG EPC1 EPC1 MFSD11 MFSD11 CCDC117 CCDC117 DMAP1 DMAP1 WAS WAS RNF8 RNF8 FGF10 FGF10 MCRS1 MCRS1 M3YT25_MUSPF M3YT25_MUSPF ABRAXAS1 ABRAXAS1 HELQ HELQ MEAF6 MEAF6 EYA4 EYA4 BCLAF1 BCLAF1 M3YU40_MUSPF M3YU40_MUSPF M3YUJ9_MUSPF M3YUJ9_MUSPF TMEM161A TMEM161A EYA3 EYA3 MBTD1 MBTD1 ZCWPW1 ZCWPW1 ANKLE1 ANKLE1 BABAM1 BABAM1 ZNHIT1 ZNHIT1 BRCC3 BRCC3 FBH1 FBH1 MAD2L2 MAD2L2 ACTR8 ACTR8 ING4 ING4 SLF2 SLF2 MMS19 MMS19 SKIL SKIL ANKRD1 ANKRD1 RUVBL1 RUVBL1 YEATS4 YEATS4 EYA2 EYA2 BABAM2 BABAM2 EGFR EGFR CEBPG CEBPG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MORF4L2Mortality factor 4 like 2. (288 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
RIF1Replication timing regulatory factor 1. (2475 aa)
ARID2AT-rich interaction domain 2. (1777 aa)
INO80DINO80 complex subunit D. (1029 aa)
PLA2R1Phospholipase A2 receptor 1. (1494 aa)
M3XND2_MUSPFGST C-terminal domain-containing protein. (174 aa)
MRNIPMRN complex interacting protein. (339 aa)
M3XNQ3_MUSPFDUF4502 domain-containing protein. (379 aa)
M3XP56_MUSPFProtein kinase domain-containing protein. (158 aa)
M3XP59_MUSPFSAM domain-containing protein. (355 aa)
PBKPDZ binding kinase. (323 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (145 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4110 aa)
M3XPZ1_MUSPFDUF4503 domain-containing protein. (370 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
M3XQT3_MUSPFUncharacterized protein. (1208 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (201 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (520 aa)
EP400E1A binding protein p400. (3107 aa)
HDAC10Histone deacetylase 10. (663 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
WDR48WD repeat domain 48. (429 aa)
FANCBFA complementation group B. (848 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (319 aa)
M3XVG1_MUSPFHelicase C-terminal domain-containing protein. (106 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
NKX3-1NK3 homeobox 1. (231 aa)
CCAR2Cell cycle and apoptosis regulator 2. (925 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
POGZPogo transposable element derived with ZNF domain. (1414 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (572 aa)
VPS72Vacuolar protein sorting 72 homolog. (364 aa)
M3XY50_MUSPFUncharacterized protein. (459 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1145 aa)
KMT5BLysine methyltransferase 5B. (940 aa)
OOEPOocyte expressed protein. (149 aa)
M3XZ29_MUSPFMOEP19 domain-containing protein. (196 aa)
SPIRE1Spire type actin nucleation factor 1. (642 aa)
PIAS4Protein inhibitor of activated STAT 4. (514 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
SIRT6Sirtuin 6. (359 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (745 aa)
PARP9Poly [ADP-ribose] polymerase. (995 aa)
HDGFL2HDGF like 2. (715 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain containing 1. (2007 aa)
RBBP8RB binding protein 8, endonuclease. (897 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
XRCC1X-ray repair cross complementing 1. (646 aa)
ING3Inhibitor of growth protein. (418 aa)
SPIRE2Spire type actin nucleation factor 2. (640 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
KMT5CLysine methyltransferase 5C. (459 aa)
M3Y878_MUSPFUncharacterized protein. (67 aa)
MRGBPMRG domain binding protein. (179 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
TRIM28Tripartite motif containing 28. (700 aa)
NFRKBNuclear factor related to kappaB binding protein. (1282 aa)
INO80INO80 complex ATPase subunit. (1561 aa)
SHLD2Shieldin complex subunit 2. (906 aa)
WRAP53WD repeat containing antisense to TP53. (539 aa)
FXR2FMR1 autosomal homolog 2. (703 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
HIC1HIC ZBTB transcriptional repressor 1. (713 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1482 aa)
M3YCX9_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (671 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
FOXM1Forkhead box M1. (760 aa)
PAXIP1PAX interacting protein 1. (1293 aa)
BRD8Bromodomain containing 8. (951 aa)
FAM168AFamily with sequence similarity 168 member A. (244 aa)
M3YEZ0_MUSPFRAD51_interact domain-containing protein. (326 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
TTI2TELO2 interacting protein 2. (508 aa)
TFPTTCF3 fusion partner. (253 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
FAM178BFamily with sequence similarity 178 member B. (654 aa)
M3YJ04_MUSPFMRG domain-containing protein. (270 aa)
M3YJ27_MUSPFUncharacterized protein. (524 aa)
FMR1Fragile X mental retardation 1. (615 aa)
DHX9DExH-box helicase 9. (1200 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
NACC2NACC family member 2. (636 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
SIRT1Sirtuin 1. (557 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (217 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
UIMC1Ubiquitin interaction motif containing 1. (644 aa)
INO80EINO80 complex subunit E. (244 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (283 aa)
ENDOGEndonuclease. (237 aa)
EPC1Enhancer of polycomb homolog. (813 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
CCDC117Coiled-coil domain containing 117. (277 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
WASWASP actin nucleation promoting factor. (501 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
MCRS1Microspherule protein 1. (462 aa)
M3YT25_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (372 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (360 aa)
HELQHelicase, POLQ like. (961 aa)
MEAF6MYST/Esa1 associated factor 6. (171 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (639 aa)
BCLAF1BCL2 associated transcription factor 1. (921 aa)
M3YU40_MUSPFUncharacterized protein. (158 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
TMEM161ATransmembrane protein 161A. (480 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa)
MBTD1Mbt domain containing 1. (628 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (624 aa)
ANKLE1Ankyrin repeat and LEM domain containing 1. (679 aa)
BABAM1BRISC and BRCA1 A complex member 1. (336 aa)
ZNHIT1Zinc finger HIT-type containing 1. (156 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (316 aa)
FBH1F-box DNA helicase 1. (1045 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
ING4Inhibitor of growth family member 4. (239 aa)
SLF2SMC5-SMC6 complex localization factor 2. (1173 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1029 aa)
SKILSKI like proto-oncogene. (664 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
YEATS4YEATS domain containing 4. (227 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (533 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
CEBPGCCAAT enhancer binding protein gamma. (146 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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