STRINGSTRING
NCK1 NCK1 IL19 IL19 BECN1 BECN1 NCK2 NCK2 NACC2 NACC2 M3YK20_MUSPF M3YK20_MUSPF SIRT1 SIRT1 BAD BAD GSDME GSDME SLC9A3R1 SLC9A3R1 BCLAF1 BCLAF1 M3YTS7_MUSPF M3YTS7_MUSPF M3YTT0_MUSPF M3YTT0_MUSPF M3YU10_MUSPF M3YU10_MUSPF FIS1 FIS1 STYXL1 STYXL1 FBH1 FBH1 SKIL SKIL SERINC3 SERINC3 PLAGL2 PLAGL2 PLEKHF1 PLEKHF1 FLCN FLCN BOK BOK DNM1L DNM1L CLU CLU RACK1 RACK1 DDIT3 DDIT3 NOX1 NOX1 PRKRA PRKRA BAX BAX NKX3-1 NKX3-1 RAD9A RAD9A PTPN2 PTPN2 PIAS4 PIAS4 FBXW9 FBXW9 M3Y0R3_MUSPF M3Y0R3_MUSPF PARK7 PARK7 CAV1 CAV1 FBXW7 FBXW7 MSX1 MSX1 S100A8 S100A8 M3YAG4_MUSPF M3YAG4_MUSPF BCAP31 BCAP31 TP53 TP53 RPS3 RPS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCK1Cytoplasmic protein. (378 aa)
IL19Interleukin 19. (177 aa)
BECN1Beclin 1. (448 aa)
NCK2Cytoplasmic protein. (380 aa)
NACC2NACC family member 2. (636 aa)
M3YK20_MUSPFWD_REPEATS_REGION domain-containing protein. (237 aa)
SIRT1Sirtuin 1. (557 aa)
BADBCL2 associated agonist of cell death. (168 aa)
GSDMEGasdermin E. (522 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
BCLAF1BCL2 associated transcription factor 1. (921 aa)
M3YTS7_MUSPFInterfer-bind domain-containing protein. (57 aa)
M3YTT0_MUSPFUncharacterized protein. (551 aa)
M3YU10_MUSPFRRM domain-containing protein. (311 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (307 aa)
FBH1F-box DNA helicase 1. (1045 aa)
SKILSKI like proto-oncogene. (664 aa)
SERINC3Serine incorporator 3. (473 aa)
PLAGL2PLAG1 like zinc finger 2. (497 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (285 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
CLUClusterin; Belongs to the clusterin family. (462 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
NOX1NADPH oxidase 1. (589 aa)
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (313 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
NKX3-1NK3 homeobox 1. (231 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
PIAS4Protein inhibitor of activated STAT 4. (514 aa)
FBXW9F-box and WD repeat domain containing 9. (459 aa)
M3Y0R3_MUSPFUncharacterized protein. (201 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
FBXW7F-box and WD repeat domain containing 7. (708 aa)
MSX1Msh homeobox 1. (303 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
M3YAG4_MUSPFEF-hand domain-containing protein; Belongs to the S-100 family. (189 aa)
BCAP31B cell receptor associated protein 31. (246 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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