STRINGSTRING
MAPK7 MAPK7 M3XMN1_MUSPF M3XMN1_MUSPF RNF6 RNF6 M3XRP6_MUSPF M3XRP6_MUSPF DAXX DAXX CHFR CHFR N4BP1 N4BP1 M3XW51_MUSPF M3XW51_MUSPF TP63 TP63 HIPK2 HIPK2 ZBTB16 ZBTB16 RNF111 RNF111 TDP2 TDP2 M3Y1L7_MUSPF M3Y1L7_MUSPF HSF1 HSF1 TP73 TP73 MORC3 MORC3 RDM1 RDM1 TP53INP1 TP53INP1 MLIP MLIP TP53 TP53 CASP8AP2 CASP8AP2 M3YFQ2_MUSPF M3YFQ2_MUSPF RPAIN RPAIN IKBKE IKBKE RPA1 RPA1 ZMYM2 ZMYM2 CHEK2 CHEK2 M3YR90_MUSPF M3YR90_MUSPF CIITA CIITA CALCOCO2 CALCOCO2 BLM BLM LRCH4 LRCH4 ISG20 ISG20 PPARGC1A PPARGC1A TRIM8 TRIM8 M3YZX8_MUSPF M3YZX8_MUSPF ANKRD2 ANKRD2 PML PML ELF4 ELF4 TP53INP2 TP53INP2 ZCCHC12 ZCCHC12 M3Z6U8_MUSPF M3Z6U8_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
M3XMN1_MUSPFUbiquitin-like domain-containing protein. (128 aa)
RNF6Ring finger protein 6. (683 aa)
M3XRP6_MUSPFRanBP2-type domain-containing protein. (264 aa)
DAXXDeath domain associated protein. (779 aa)
CHFRCheckpoint with forkhead and ring finger domains. (632 aa)
N4BP1NEDD4 binding protein 1. (810 aa)
M3XW51_MUSPFUncharacterized protein. (553 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (586 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
RNF111Ring finger protein 111. (985 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (360 aa)
M3Y1L7_MUSPFSprT-like domain-containing protein. (535 aa)
HSF1Heat shock transcription factor 1. (555 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
MORC3MORC family CW-type zinc finger 3. (765 aa)
RDM1RAD52 motif containing 1. (286 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
MLIPMuscular LMNA interacting protein. (793 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
CASP8AP2Caspase 8 associated protein 2. (1971 aa)
M3YFQ2_MUSPFSmall ubiquitin-related modifier. (95 aa)
RPAINRPA interacting protein. (193 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (719 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
ZMYM2Zinc finger MYM-type containing 2. (1295 aa)
CHEK2Checkpoint kinase 2. (544 aa)
M3YR90_MUSPFSmall ubiquitin-related modifier. (95 aa)
CIITAClass II major histocompatibility complex transactivator. (1109 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (495 aa)
BLMBLM RecQ like helicase. (1221 aa)
LRCH4Leucine rich repeats and calponin homology domain containing 4. (691 aa)
ISG20Interferon stimulated exonuclease gene 20. (171 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
TRIM8Tripartite motif containing 8. (551 aa)
M3YZX8_MUSPFUncharacterized protein. (144 aa)
ANKRD2Ankyrin repeat domain 2. (335 aa)
PMLPromyelocytic leukemia. (876 aa)
ELF4E74 like ETS transcription factor 4. (661 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (224 aa)
ZCCHC12Zinc finger CCHC-type containing 12. (403 aa)
M3Z6U8_MUSPFSmall ubiquitin-related modifier. (100 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (18%) [HD]