(77 nodes) Exocytic vesicle network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M3XYP8_MUSPF	Uncharacterized protein. (506 aa)
	BTBD8	BTB domain containing 8. (1406 aa)
	SLC18A1	Solute carrier family 18 member A1. (524 aa)
	SYNJ2	Synaptojanin 2. (1301 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	SV2A	Synaptic vesicle glycoprotein 2A. (742 aa)
	DISC1	DISC1 scaffold protein. (865 aa)
	SV2C	Synaptic vesicle glycoprotein 2C. (724 aa)
	LMAN2	Lectin, mannose binding 2. (356 aa)
	CACFD1	Calcium channel flower domain containing 1. (233 aa)
	M3YLS9_MUSPF	Synapsin_C domain-containing protein. (324 aa)
	M3YLT1_MUSPF	Uncharacterized protein. (250 aa)
	PRRT2	Proline rich transmembrane protein 2. (349 aa)
	DOC2A	Double C2 domain alpha. (416 aa)
	RAB1A	RAB1A, member RAS oncogene family. (251 aa)
	KIRREL3	Kirre like nephrin family adhesion molecule 3. (745 aa)
	RAB11B	RAB11B, member RAS oncogene family. (218 aa)
	RAB3C	RAB3C, member RAS oncogene family. (227 aa)
	M3Y7S4_MUSPF	HSac2 domain-containing protein. (149 aa)
	M3Y9V8_MUSPF	V-SNARE coiled-coil homology domain-containing protein. (119 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	STON2	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (952 aa)
	MX2	MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (717 aa)
	MX1	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (670 aa)
	RAB6B	RAB6B, member RAS oncogene family. (198 aa)
	RAB6A	RAB6A, member RAS oncogene family. (208 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (660 aa)
	CLN3	Battenin. (438 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	M3YPF6_MUSPF	Synaptogyrin. (226 aa)
	SYN1	Synapsin I. (704 aa)
	UNC13D	Unc-13 homolog D. (1091 aa)
	SYP	Synaptophysin. (314 aa)
	PRRT1	Proline rich transmembrane protein 1. (306 aa)
	SEPTIN8	Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (430 aa)
	M3YGL9_MUSPF	Uncharacterized protein. (216 aa)
	RAB1B	RAB1B, member RAS oncoprotein family. (210 aa)
	SEMA4C	Semaphorin 4C; Belongs to the semaphorin family. (867 aa)
	STX6	Syntaxin 6; Belongs to the syntaxin family. (255 aa)
	SLC17A8	Solute carrier family 17 member 8. (588 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	LOC101671843	ENTH domain-containing protein. (443 aa)
	SYNPR	Synaptoporin. (265 aa)
	SYN2	Synapsin II. (388 aa)
	M3Z1C4_MUSPF	Sec2p domain-containing protein. (472 aa)
	SV2B	Synaptic vesicle glycoprotein 2B. (714 aa)
	BCL2L1	BCL2 like 1. (233 aa)
	AMPH	Amphiphysin. (676 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	RNF112	Ring finger protein 112. (605 aa)
	SYT10	Synaptotagmin 10. (523 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	RAB8B	RAB8B, member RAS oncogene family. (207 aa)
	M3XNV3_MUSPF	Uncharacterized protein. (93 aa)
	M3XNV5_MUSPF	PDE4_UCR domain-containing protein. (232 aa)
	PDE4B	Phosphodiesterase. (544 aa)
	ANXA13	Annexin. (287 aa)
	RPH3A	Rabphilin 3A. (702 aa)
	TMEM163	Transmembrane protein 163. (178 aa)
	SLC17A7	Solute carrier family 17 member 7. (560 aa)
	RAB3A	RAB3A, member RAS oncogene family. (220 aa)
	STX12	Syntaxin 12; Belongs to the syntaxin family. (274 aa)
	SYNGR3	Synaptogyrin. (229 aa)
	TSPOAP1	TSPO associated protein 1. (1850 aa)
	PPT1	Palmitoyl-protein thioesterase 1. (306 aa)
	SYT7	Synaptotagmin 7. (611 aa)
	RAB3IL1	RAB3A interacting protein like 1. (429 aa)
	SLC17A6	Solute carrier family 17 member 6. (582 aa)
	MME	Membrane metalloendopeptidase. (749 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	TPRG1	Tumor protein p63 regulated 1. (332 aa)
	SVOP	SV2 related protein. (548 aa)
	SLC6A17	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
	CADM1	Cell adhesion molecule 1. (427 aa)
	M3XY67_MUSPF	Double C2-like domain-containing protein. (383 aa)
	RIMBP2	RIMS binding protein 2. (1441 aa)
	STX10	Syntaxin 10. (250 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPH	MX1	ENSMPUP00000018017	ENSMPUP00000008707	Amphiphysin.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.409
AMPH	MX2	ENSMPUP00000018017	ENSMPUP00000008646	Amphiphysin.	MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.409
AMPH	PICALM	ENSMPUP00000018017	ENSMPUP00000009962	Amphiphysin.	Phosphatidylinositol binding clathrin assembly protein.	0.491
AMPH	STON2	ENSMPUP00000018017	ENSMPUP00000008565	Amphiphysin.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.461
AMPH	SYNJ2	ENSMPUP00000018017	ENSMPUP00000005285	Amphiphysin.	Synaptojanin 2.	0.759
CLN3	PPT1	ENSMPUP00000012633	ENSMPUP00000014165	Battenin.	Palmitoyl-protein thioesterase 1.	0.745
DISC1	M3XNV3_MUSPF	ENSMPUP00000005538	ENSMPUP00000000753	DISC1 scaffold protein.	Uncharacterized protein.	0.500
DISC1	M3XNV5_MUSPF	ENSMPUP00000005538	ENSMPUP00000000755	DISC1 scaffold protein.	PDE4_UCR domain-containing protein.	0.500
DISC1	MME	ENSMPUP00000005538	ENSMPUP00000002718	DISC1 scaffold protein.	Membrane metalloendopeptidase.	0.515
DISC1	PDE4B	ENSMPUP00000005538	ENSMPUP00000000758	DISC1 scaffold protein.	Phosphodiesterase.	0.500
DOC2A	PRRT2	ENSMPUP00000012449	ENSMPUP00000012361	Double C2 domain alpha.	Proline rich transmembrane protein 2.	0.467
DOC2A	RAB3A	ENSMPUP00000012449	ENSMPUP00000015602	Double C2 domain alpha.	RAB3A, member RAS oncogene family.	0.407
DOC2A	RAB3C	ENSMPUP00000012449	ENSMPUP00000007353	Double C2 domain alpha.	RAB3C, member RAS oncogene family.	0.426
GNAI1	GNAI2	ENSMPUP00000018173	ENSMPUP00000013014	G protein subunit alpha i1.	G protein subunit alpha i2.	0.815
GNAI1	GNAI3	ENSMPUP00000018173	ENSMPUP00000003264	G protein subunit alpha i1.	G protein subunit alpha i3.	0.815
GNAI2	GNAI1	ENSMPUP00000013014	ENSMPUP00000018173	G protein subunit alpha i2.	G protein subunit alpha i1.	0.815
GNAI2	GNAI3	ENSMPUP00000013014	ENSMPUP00000003264	G protein subunit alpha i2.	G protein subunit alpha i3.	0.816
GNAI3	GNAI1	ENSMPUP00000003264	ENSMPUP00000018173	G protein subunit alpha i3.	G protein subunit alpha i1.	0.815
GNAI3	GNAI2	ENSMPUP00000003264	ENSMPUP00000013014	G protein subunit alpha i3.	G protein subunit alpha i2.	0.816
LMAN2	PPT1	ENSMPUP00000012099	ENSMPUP00000014165	Lectin, mannose binding 2.	Palmitoyl-protein thioesterase 1.	0.439