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CACNA1D CACNA1D KCNA4 KCNA4 KCNA3 KCNA3 KCNA2 KCNA2 KCNA10 KCNA10 KCNS2 KCNS2 KCNS3 KCNS3 KCNF1 KCNF1 KCNA5 KCNA5 KCNA1 KCNA1 KCNA6 KCNA6 CACNA1C CACNA1C RYR1 RYR1 KCNS1 KCNS1 KCNB1 KCNB1 KCNG1 KCNG1 KCNC2 KCNC2 TRPC3 TRPC3 HCN4 HCN4 ITPR1 ITPR1 CACNA1H CACNA1H CATSPER4 CATSPER4 CACNA1G CACNA1G CACNA1B CACNA1B TRPC4 TRPC4 KCNH6 KCNH6 SCN4A SCN4A KCNH3 KCNH3 HCN1 HCN1 KCNQ4 KCNQ4 CACNA1F CACNA1F KCND1 KCND1 KCNC1 KCNC1 CACNA1I CACNA1I RYR2 RYR2 TRPC1 TRPC1 CNGA2 CNGA2 CACNA1E CACNA1E CATSPER1 CATSPER1 NALCN NALCN CNGA3 CNGA3 TRPM1 TRPM1 CACNA1S CACNA1S KCNH4 KCNH4 CATSPER2 CATSPER2 M3YG43_MUSPF M3YG43_MUSPF ITPR2 ITPR2 TRPA1 TRPA1 M3YFZ5_MUSPF M3YFZ5_MUSPF TRPM2 TRPM2 TRPV2 TRPV2 KCNU1 KCNU1 CATSPER3 CATSPER3 TRPC7 TRPC7 HCN2 HCN2 M3YD19_MUSPF M3YD19_MUSPF TRPM3 TRPM3 KCNG4 KCNG4 TRPM6 TRPM6 TRPV6 TRPV6 M3YAI1_MUSPF M3YAI1_MUSPF KCNQ2 KCNQ2 RYR3 RYR3 SCN8A SCN8A TRPM7 TRPM7 KCNH2 KCNH2 TRPC6 TRPC6 KCND2 KCND2 KCNH5 KCNH5 M3Y3B6_MUSPF M3Y3B6_MUSPF CNGA4 CNGA4 KCNV1 KCNV1 HCN3 HCN3 CNGA1 CNGA1 KCNV2 KCNV2 TRPM5 TRPM5 KCNQ1 KCNQ1 KCND3 KCND3 TPCN2 TPCN2 KCNQ5 KCNQ5 TRPC5 TRPC5 TRPV4 TRPV4 KCNMA1 KCNMA1 KCNC4 KCNC4 CACNA1A CACNA1A KCNA7 KCNA7 M3XVK2_MUSPF M3XVK2_MUSPF TRPM4 TRPM4 TPCN1 TPCN1 SCN5A SCN5A SCN10A SCN10A M3XTT7_MUSPF M3XTT7_MUSPF M3XTT1_MUSPF M3XTT1_MUSPF ITPR3 ITPR3 TRPM8 TRPM8 HVCN1 HVCN1 KCNC3 KCNC3 KCNQ3 KCNQ3 KCNH8 KCNH8 SCN7A SCN7A SCN9A SCN9A SCN1A SCN1A SCN2A SCN2A SCN3A SCN3A KCNH7 KCNH7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2217 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] (654 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (439 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (474 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family [...] (601 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (528 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1479 aa)
RYR1Ryanodine receptor 1. (4983 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (498 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (516 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (612 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (866 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (987 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2143 aa)
CATSPER4Cation channel sperm associated 4. (449 aa)
CACNA1GCalcium voltage-gated channel subunit alpha1 G. (2177 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (1971 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (927 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1840 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (1042 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (609 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1986 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (650 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2024 aa)
RYR2Ryanodine receptor 2. (4966 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2463 aa)
CATSPER1Cation channel sperm associated 1. (858 aa)
NALCNSodium leak channel, non-selective. (1737 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (729 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1635 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1795 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1017 aa)
CATSPER2Cation channel sperm associated 2. (533 aa)
M3YG43_MUSPFIon_trans domain-containing protein. (166 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
M3YFZ5_MUSPFIon_trans domain-containing protein; Belongs to the potassium channel family. (687 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1496 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (766 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1127 aa)
CATSPER3Cation channel sperm associated 3. (367 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (807 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (763 aa)
M3YD19_MUSPFUncharacterized protein. (829 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1673 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (511 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2031 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
M3YAI1_MUSPFANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (735 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (770 aa)
RYR3Ryanodine receptor 3. (4863 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1738 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in rodent heart. Mediates the major part of the dendritic A-type current I(SA) in brain neurons (By similarity). This current is activated at membrane potentials that are below the threshold for action potentials. It regulates neuronal excitability, prolongs the latency before the first spike in a series of action potentials, regulates the frequency of repetitive action potential firing, shortens t [...] (399 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
M3Y3B6_MUSPFIon_trans domain-containing protein. (188 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (571 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (781 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (658 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (419 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1152 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (655 aa)
TPCN2Uncharacterized protein. (746 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (803 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1020 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (626 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2496 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (557 aa)
M3XVK2_MUSPFUncharacterized protein. (991 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1211 aa)
TPCN1Two pore segment channel 1. (861 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1954 aa)
M3XTT7_MUSPFSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (460 aa)
M3XTT1_MUSPFUncharacterized protein. (1131 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
HVCN1Hydrogen voltage gated channel 1. (271 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (663 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (743 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1108 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1685 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1989 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1938 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1924 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1092 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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