STRINGSTRING
CNTF CNTF CLCF1 CLCF1 PRL PRL LEP LEP M3YJF2_MUSPF M3YJF2_MUSPF M3YJG0_MUSPF M3YJG0_MUSPF M3YKM4_MUSPF M3YKM4_MUSPF M3YKM8_MUSPF M3YKM8_MUSPF IL27 IL27 OSM OSM LIF LIF IL6 IL6 LOC101692325 LOC101692325 CSF3 CSF3 EPO EPO IFNE IFNE M3YX15_MUSPF M3YX15_MUSPF M3YX17_MUSPF M3YX17_MUSPF IL15 IL15 IL21 IL21 M3Z722_MUSPF M3Z722_MUSPF M3Z715_MUSPF M3Z715_MUSPF IFNG-2 IFNG-2 IFNG IFNG M3Z1D8_MUSPF M3Z1D8_MUSPF IL22 IL22 LOC101676633 LOC101676633 LOC101674940 LOC101674940 M3Z7X0_MUSPF M3Z7X0_MUSPF LOC101684645 LOC101684645 LOC101684365 LOC101684365 M3Z7W2_MUSPF M3Z7W2_MUSPF LOC101684074 LOC101684074 M3Z7V7_MUSPF M3Z7V7_MUSPF IFNK IFNK IFNB1 IFNB1 LOC101678795 LOC101678795 LOC101678496 LOC101678496 M3Z729_MUSPF M3Z729_MUSPF CSF1 CSF1 IL12A IL12A THPO THPO FLT3LG FLT3LG IL23A IL23A IL2 IL2 IL11 IL11 KITLG KITLG IL24 IL24 IL20 IL20 IL19 IL19 IL10 IL10 IL4 IL4 IL13 IL13 CSF2 CSF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNTFCiliary neurotrophic factor. (200 aa)
CLCF1Cardiotrophin like cytokine factor 1. (281 aa)
PRLProlactin. (231 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
M3YJF2_MUSPFUncharacterized protein. (140 aa)
M3YJG0_MUSPFUncharacterized protein. (108 aa)
M3YKM4_MUSPFUncharacterized protein. (52 aa)
M3YKM8_MUSPFUncharacterized protein. (172 aa)
IL27Interleukin 27. (237 aa)
OSMOncostatin M. (238 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
LOC101692325Uncharacterized protein. (216 aa)
CSF3Colony stimulating factor 3. (204 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
IFNEInterferon epsilon. (181 aa)
M3YX15_MUSPFUncharacterized protein. (161 aa)
M3YX17_MUSPFUncharacterized protein. (158 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
M3Z722_MUSPFUncharacterized protein. (187 aa)
M3Z715_MUSPFUncharacterized protein. (198 aa)
IFNG-2Uncharacterized protein. (187 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
M3Z1D8_MUSPFUncharacterized protein. (40 aa)
IL22Interleukin 22. (178 aa)
LOC101676633Uncharacterized protein. (187 aa)
LOC101674940Uncharacterized protein. (187 aa)
M3Z7X0_MUSPFUncharacterized protein. (187 aa)
LOC101684645Uncharacterized protein. (187 aa)
LOC101684365Uncharacterized protein. (187 aa)
M3Z7W2_MUSPFUncharacterized protein. (187 aa)
LOC101684074Uncharacterized protein. (187 aa)
M3Z7V7_MUSPFUncharacterized protein. (187 aa)
IFNKInterferon kappa. (202 aa)
IFNB1Interferon beta. (186 aa)
LOC101678795Uncharacterized protein. (182 aa)
LOC101678496Uncharacterized protein. (187 aa)
M3Z729_MUSPFUncharacterized protein. (187 aa)
CSF1Colony stimulating factor 1. (517 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
THPOThrombopoietin. (325 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (291 aa)
IL23AInterleukin 23 subunit alpha. (195 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
IL11Interleukin 11. (197 aa)
KITLGKIT ligand. (274 aa)
IL24Interleukin 24. (183 aa)
IL20Interleukin 20. (176 aa)
IL19Interleukin 19. (177 aa)
IL10Interleukin 10. (220 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
IL13Interleukin 13. (128 aa)
CSF2Colony stimulating factor 2. (148 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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