STRINGSTRING
M3Y653_MUSPF M3Y653_MUSPF EGFR EGFR HCK HCK SRC SRC LCK LCK ALK ALK FGR FGR FES FES JAK3 JAK3 EPHB4 EPHB4 NTRK3 NTRK3 TEK TEK ERBB2 ERBB2 ROS1 ROS1 CSF1R CSF1R PDGFRB PDGFRB TIE1 TIE1 ITK ITK MST1R MST1R ABL1 ABL1 FER FER FGFR4 FGFR4 DDR1 DDR1 ZAP70 ZAP70 FGFR3 FGFR3 IGF1R IGF1R LYN LYN FRK FRK FYN FYN TNK1 TNK1 FGFR1 FGFR1 MERTK MERTK EPHB1 EPHB1 EPHA7 EPHA7 TYRO3 TYRO3 INSR INSR SRMS SRMS PTK6 PTK6 EPHA3 EPHA3 ERBB4 ERBB4 MUSK MUSK MET MET EPHA1 EPHA1 TYK2 TYK2 KIT KIT PDGFRA PDGFRA YES1 YES1 TEC TEC TXK TXK ABL2 ABL2 KDR KDR FLT3 FLT3 JAK2 JAK2 MATK MATK TNK2 TNK2 DDR2 DDR2 INSRR INSRR NTRK1 NTRK1 FGFR2 FGFR2 EPHB3 EPHB3 EPHA6 EPHA6 BMX BMX BTK BTK PTK2 PTK2 BLK BLK EPHA5 EPHA5 PTK2B PTK2B JAK1 JAK1 FLT4 FLT4 EPHB2 EPHB2 EPHA8 EPHA8 EPHA2 EPHA2 EPHA4 EPHA4 RET RET CSK CSK AXL AXL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3Y653_MUSPFProtein kinase domain-containing protein. (212 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
HCKTyrosine-protein kinase. (504 aa)
SRCTyrosine-protein kinase. (536 aa)
LCKTyrosine-protein kinase. (509 aa)
ALKTyrosine-protein kinase receptor. (1633 aa)
FGRTyrosine-protein kinase. (526 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
JAK3Tyrosine-protein kinase. (1107 aa)
EPHB4EPH receptor B4. (987 aa)
NTRK3Tyrosine-protein kinase receptor. (781 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
ERBB2Receptor protein-tyrosine kinase. (1260 aa)
ROS1Tyrosine-protein kinase receptor. (2342 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1137 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (994 aa)
ITKTyrosine-protein kinase. (620 aa)
MST1RMacrophage stimulating 1 receptor. (1399 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (823 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (919 aa)
ZAP70Tyrosine-protein kinase. (616 aa)
FGFR3Fibroblast growth factor receptor. (802 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
LYNTyrosine-protein kinase. (512 aa)
FRKTyrosine-protein kinase. (515 aa)
FYNTyrosine-protein kinase. (537 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (664 aa)
FGFR1Fibroblast growth factor receptor. (856 aa)
MERTKMER proto-oncogene, tyrosine kinase. (990 aa)
EPHB1EPH receptor B1. (984 aa)
EPHA7EPH receptor A7. (998 aa)
TYRO3TYRO3 protein tyrosine kinase. (870 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
SRMSTyrosine-protein kinase. (507 aa)
PTK6Tyrosine-protein kinase. (444 aa)
EPHA3EPH receptor A3. (1000 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
MUSKMuscle associated receptor tyrosine kinase. (950 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
EPHA1EPH receptor A1. (976 aa)
TYK2Tyrosine-protein kinase. (1182 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (948 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
YES1Tyrosine-protein kinase. (541 aa)
TECTyrosine-protein kinase. (631 aa)
TXKTyrosine-protein kinase. (551 aa)
ABL2Tyrosine-protein kinase. (1079 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
MATKTyrosine-protein kinase. (447 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1105 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (924 aa)
INSRRTyrosine-protein kinase receptor. (1358 aa)
NTRK1Tyrosine-protein kinase receptor. (727 aa)
FGFR2Fibroblast growth factor receptor. (842 aa)
EPHB3EPH receptor B3. (959 aa)
EPHA6EPH receptor A6. (752 aa)
BMXTyrosine-protein kinase. (655 aa)
BTKTyrosine-protein kinase. (659 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
BLKTyrosine-protein kinase. (500 aa)
EPHA5EPH receptor A5. (1037 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
EPHB2EPH receptor B2. (963 aa)
EPHA8EPH receptor A8. (930 aa)
EPHA2EPH receptor A2. (975 aa)
EPHA4EPH receptor A4. (986 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1028 aa)
CSKTyrosine-protein kinase. (450 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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