STRINGSTRING
SUPT16H SUPT16H SSRP1 SSRP1 GTF2H3 GTF2H3 GTF2F2 GTF2F2 EAF1 EAF1 AFF1 AFF1 CCNT2 CCNT2 POLR2H POLR2H M3XV89_MUSPF M3XV89_MUSPF NCBP2 NCBP2 POLR2C POLR2C CDC73 CDC73 POLR2B POLR2B EAF2 EAF2 GTF2H5 GTF2H5 POLR2I POLR2I ERCC2 ERCC2 NCBP1 NCBP1 MNAT1 MNAT1 MLLT1 MLLT1 GTF2F1 GTF2F1 NELFCD NELFCD LEO1 LEO1 CCNH CCNH RTF1 RTF1 POLR2E POLR2E POLR2A POLR2A ELOC ELOC AFF4 AFF4 NELFE NELFE WDR61 WDR61 NELFA NELFA ERCC3 ERCC3 AFF3 AFF3 CTR9 CTR9 POLR2F POLR2F POLR2G POLR2G CDK9 CDK9 GTF2H1 GTF2H1 SUPT6H SUPT6H M3YSQ4_MUSPF M3YSQ4_MUSPF CDK7 CDK7 CCNT1 CCNT1 NELFB NELFB ELOB ELOB SUPT4H1 SUPT4H1 ELL ELL ELOA ELOA MLLT3 MLLT3 CTDP1 CTDP1 POLR2D POLR2D IWS1 IWS1 SUPT5H SUPT5H PAF1 PAF1 NCBP2L NCBP2L M3Z6G7_MUSPF M3Z6G7_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
EAF1ELL associated factor 1. (268 aa)
AFF1AF4/FMR2 family member 1. (1226 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (759 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
M3XV89_MUSPFUncharacterized protein; Belongs to the cyclin family. (501 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
CDC73Cell division cycle 73. (531 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
EAF2ELL associated factor 2. (264 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
MLLT1MLLT1 super elongation complex subunit. (524 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
NELFCDNegative elongation factor complex member C/D. (575 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (664 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
AFF4AF4/FMR2 family member 4. (1167 aa)
NELFENegative elongation factor complex member E. (389 aa)
WDR61WD repeat domain 61. (305 aa)
NELFANegative elongation factor complex member A. (532 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
AFF3AF4/FMR2 family member 3. (1217 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
GTF2H1General transcription factor IIH subunit 1. (547 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
M3YSQ4_MUSPFGeneral transcription factor IIH subunit. (395 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (349 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (727 aa)
NELFBNegative elongation factor complex member B. (492 aa)
ELOBElongin B. (118 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (120 aa)
ELLElongation factor for RNA polymerase II. (613 aa)
ELOAElongin A. (816 aa)
MLLT3MLLT3 super elongation complex subunit. (464 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (759 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (846 aa)
SUPT5HSPT5 homolog, DSIF elongation factor subunit. (1087 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (554 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
M3Z6G7_MUSPFUncharacterized protein. (417 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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