STRINGSTRING
M3YWQ4_MUSPF M3YWQ4_MUSPF RNF222 RNF222 M3Z785_MUSPF M3Z785_MUSPF FNDC3A FNDC3A TRIB3 TRIB3 SRC SRC AKT2 AKT2 PLCG1 PLCG1 AXL AXL ELMO2 ELMO2 CYFIP1 CYFIP1 PIK3CA PIK3CA FNDC3B FNDC3B PRKCD PRKCD ACTB ACTB MTOR MTOR SZRD1 SZRD1 PRR5 PRR5 ACTL8 ACTL8 NCF1 NCF1 HSH2D HSH2D M3YX33_MUSPF M3YX33_MUSPF HSPB1 HSPB1 PAK1 PAK1 AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF WASF2 WASF2 STX12 STX12 MLST8 MLST8 PDPK1 PDPK1 RICTOR RICTOR STX7 STX7 PIK3R1 PIK3R1 PRKCA PRKCA MAPKAP1 MAPKAP1 CRK CRK ROCK2 ROCK2 SPHK1 SPHK1 CYFIP2 CYFIP2 VEGFB VEGFB M3YP24_MUSPF M3YP24_MUSPF TENM2 TENM2 MAPKAPK3 MAPKAPK3 VEGFA VEGFA NCF4 NCF4 ABI1 ABI1 PRKCB PRKCB VAV2 VAV2 VEGFC VEGFC CALM2 CALM2 BAIAP2 BAIAP2 NCF2 NCF2 ACTG1 ACTG1 CTNNB1 CTNNB1 TGFB1I1 TGFB1I1 SHF SHF TENM3 TENM3 JUP JUP NCK2 NCK2 M3YH29_MUSPF M3YH29_MUSPF KRAS KRAS FYN FYN WASF1 WASF1 SHC2 SHC2 MAPKAPK2 MAPKAPK2 BCAR1 BCAR1 NCK1 NCK1 PGF PGF PIK3CB PIK3CB SRMS SRMS PTK6 PTK6 CYBA CYBA CALM1 CALM1 M3Y9K9_MUSPF M3Y9K9_MUSPF TENM4 TENM4 RASA1 RASA1 ELMO1 ELMO1 PRKCZ PRKCZ NOS3 NOS3 SHE SHE CAV1 CAV1 VAV1 VAV1 EFS EFS CASS4 CASS4 M3Y484_MUSPF M3Y484_MUSPF NRP1 NRP1 PRKACB PRKACB CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF ELMO3 ELMO3 NCKAP1L NCKAP1L ROCK1 ROCK1 CALM3 CALM3 KDR KDR SHD SHD CDH5 CDH5 FLT1 FLT1 M3XYN0_MUSPF M3XYN0_MUSPF MAPK13 MAPK13 PAK3 PAK3 ARVCF ARVCF SH2D2A SH2D2A MAPK14 MAPK14 PAK2 PAK2 ITGAV ITGAV M3XWP6_MUSPF M3XWP6_MUSPF PXN PXN PRKACA PRKACA VEGFD VEGFD M3XTE0_MUSPF M3XTE0_MUSPF MAPK12 MAPK12 MAPK11 MAPK11 AKT1 AKT1 NCKAP1 NCKAP1 PTK2 PTK2 M3XR07_MUSPF M3XR07_MUSPF TENM1 TENM1 M3XQI2_MUSPF M3XQI2_MUSPF M3XQ60_MUSPF M3XQ60_MUSPF WASF3 WASF3 PTK2B PTK2B NEDD9 NEDD9 FLT4 FLT4 NRP2 NRP2 ABI2 ABI2 LPXN LPXN CTNND1 CTNND1 VAV3 VAV3 LOC101676297 LOC101676297
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3YWQ4_MUSPFUncharacterized protein; Belongs to the actin family. (338 aa)
RNF222Ring finger protein 222. (224 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
TRIB3Tribbles pseudokinase 3. (358 aa)
SRCTyrosine-protein kinase. (536 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
PRKCDProtein kinase C. (730 aa)
ACTBActin beta. (375 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
SZRD1SUZ RNA binding domain containing 1. (153 aa)
PRR5Proline rich 5. (389 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
NCF1Neutrophil cytosolic factor 1. (391 aa)
HSH2DHematopoietic SH2 domain containing. (346 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
WASF2WASP family member 2. (498 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (274 aa)
MLST8MTOR associated protein, LST8 homolog. (328 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
SPHK1Sphingosine kinase 1. (386 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
M3YP24_MUSPFTeneurin N-terminal domain-containing protein. (172 aa)
TENM2Teneurin transmembrane protein 2. (2624 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
ABI1Abl interactor 1. (507 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
VAV2Vav guanine nucleotide exchange factor 2. (834 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (370 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
BAIAP2BAI1-associated protein 2. (500 aa)
NCF2Neutrophil cytosolic factor 2. (620 aa)
ACTG1Actin gamma 1. (375 aa)
CTNNB1Catenin beta 1. (781 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
SHFSrc homology 2 domain containing F. (474 aa)
TENM3Teneurin transmembrane protein 3. (2721 aa)
JUPJunction plakoglobin. (744 aa)
NCK2Cytoplasmic protein. (380 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
FYNTyrosine-protein kinase. (537 aa)
WASF1WASP family member 1. (559 aa)
SHC2Uncharacterized protein. (539 aa)
MAPKAPK2MAPK activated protein kinase 2. (319 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (867 aa)
NCK1Cytoplasmic protein. (378 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SRMSTyrosine-protein kinase. (507 aa)
PTK6Tyrosine-protein kinase. (444 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
M3Y9K9_MUSPFIntegrin beta; Belongs to the integrin beta chain family. (645 aa)
TENM4Teneurin transmembrane protein 4. (2855 aa)
RASA1RAS p21 protein activator 1. (1042 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
SHESrc homology 2 domain containing E. (449 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
EFSEmbryonal Fyn-associated substrate. (551 aa)
CASS4Cas scaffold protein family member 4. (813 aa)
M3Y484_MUSPFSH2 domain-containing protein. (468 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
ELMO3Engulfment and cell motility 3. (722 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
FLT1Receptor protein-tyrosine kinase. (1338 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PAK3P21 (RAC1) activated kinase 3. (583 aa)
ARVCFARVCF delta catenin family member. (960 aa)
SH2D2ASH2 domain containing 2A. (424 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
M3XWP6_MUSPFUncharacterized protein. (120 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (590 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
M3XTE0_MUSPFUncharacterized protein; Belongs to the actin family. (348 aa)
MAPK12Mitogen-activated protein kinase. (287 aa)
MAPK11Mitogen-activated protein kinase. (434 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NCKAP1NCK associated protein 1. (1126 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
M3XR07_MUSPFUncharacterized protein; Belongs to the actin family. (362 aa)
TENM1Uncharacterized protein. (2400 aa)
M3XQI2_MUSPFTeneurin N-terminal domain-containing protein. (264 aa)
M3XQ60_MUSPFUncharacterized protein. (47 aa)
WASF3WASP family member 3. (406 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (835 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
ABI2Abl interactor 2. (468 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (414 aa)
CTNND1Catenin delta 1. (967 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
LOC101676297Uncharacterized protein. (1513 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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