STRINGSTRING
FGF10 FGF10 M3YR72_MUSPF M3YR72_MUSPF GRB2 GRB2 FGF22 FGF22 FGFR1 FGFR1 FGF23 FGF23 FGF6 FGF6 FGF1 FGF1 FGF5 FGF5 M3XZV6_MUSPF M3XZV6_MUSPF FGF4 FGF4 FGF17 FGF17 PTPN11 PTPN11 GAB1 GAB1 FGF8 FGF8 FGF9 FGF9 FGF2 FGF2 FRS2 FRS2 FGF20 FGF20 PIK3CA PIK3CA PIK3R1 PIK3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
M3YR72_MUSPFUncharacterized protein. (542 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
FGFR1Fibroblast growth factor receptor. (856 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (265 aa)
M3XZV6_MUSPFFibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
GAB1GRB2 associated binding protein 1. (648 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FRS2Fibroblast growth factor receptor substrate 2. (517 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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