(23 nodes) Translesion synthesis by POLK network (Mustela putorius)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC101686900	Ubiquitin-like domain-containing protein. (127 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	MEIOB	Meiosis specific with OB-fold. (471 aa)
	RPA2	Replication protein A2. (270 aa)
	KXD1	KxDL motif containing 1. (182 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ATAD5	ATPase family AAA domain containing 5. (1892 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
	M3YMN0_MUSPF	Ubiquitin-like domain-containing protein. (124 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1254 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	REV3L	REV3 like, DNA directed polymerase zeta catalytic subunit. (3130 aa)
	M3YFD0_MUSPF	Uncharacterized protein. (260 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RFC1	Replication factor C subunit 1. (1155 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	RFC5	Replication factor C subunit 5. (340 aa)
	RFC4	Replication factor C subunit 4. (360 aa)
	M3XQS3_MUSPF	Uncharacterized protein. (272 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	POLK	DNA polymerase kappa. (870 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	M3XQS3_MUSPF	ENSMPUP00000014578	ENSMPUP00000001423	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.567
ATAD5	MAD2L2	ENSMPUP00000014578	ENSMPUP00000016318	ATPase family AAA domain containing 5.	Mitotic arrest deficient 2 like 2.	0.594
ATAD5	MEIOB	ENSMPUP00000014578	ENSMPUP00000015459	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.683
ATAD5	PCNA	ENSMPUP00000014578	ENSMPUP00000006142	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.957
ATAD5	POLK	ENSMPUP00000014578	ENSMPUP00000005596	ATPase family AAA domain containing 5.	DNA polymerase kappa.	0.600
ATAD5	REV1	ENSMPUP00000014578	ENSMPUP00000011987	ATPase family AAA domain containing 5.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.612
ATAD5	REV3L	ENSMPUP00000014578	ENSMPUP00000010122	ATPase family AAA domain containing 5.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.699
ATAD5	RFC1	ENSMPUP00000014578	ENSMPUP00000005982	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.650
ATAD5	RFC2	ENSMPUP00000014578	ENSMPUP00000016010	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.975
ATAD5	RFC3	ENSMPUP00000014578	ENSMPUP00000001870	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.968
ATAD5	RFC4	ENSMPUP00000014578	ENSMPUP00000003304	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.989
ATAD5	RFC5	ENSMPUP00000014578	ENSMPUP00000002812	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.961
ATAD5	RPA1	ENSMPUP00000014578	ENSMPUP00000013022	ATPase family AAA domain containing 5.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.683
ATAD5	RPA2	ENSMPUP00000014578	ENSMPUP00000015452	ATPase family AAA domain containing 5.	Replication protein A2.	0.521
ATAD5	RPS27A	ENSMPUP00000014578	ENSMPUP00000010391	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.548
KXD1	LOC101686900	ENSMPUP00000015426	ENSMPUP00000018679	KxDL motif containing 1.	Ubiquitin-like domain-containing protein.	0.898
KXD1	M3YFD0_MUSPF	ENSMPUP00000015426	ENSMPUP00000010037	KxDL motif containing 1.	Uncharacterized protein.	0.748
KXD1	M3YMN0_MUSPF	ENSMPUP00000015426	ENSMPUP00000012587	KxDL motif containing 1.	Ubiquitin-like domain-containing protein.	0.822
KXD1	RPS27A	ENSMPUP00000015426	ENSMPUP00000010391	KxDL motif containing 1.	Ubiquitin-like domain-containing protein.	0.949
KXD1	UBA52	ENSMPUP00000015426	ENSMPUP00000015416	KxDL motif containing 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.898