STRINGSTRING
CCNA1 CCNA1 SGK1 SGK1 USP7 USP7 RICTOR RICTOR RFFL RFFL PDPK1 PDPK1 MLST8 MLST8 UBA52 UBA52 KXD1 KXD1 TXNDC11 TXNDC11 AKT3 AKT3 AKT2 AKT2 MDM2 MDM2 PPP2R1A PPP2R1A CCNA2 CCNA2 MTOR MTOR PRR5 PRR5 MAPKAP1 MAPKAP1 CDK3 CDK3 CCNG1 CCNG1 ATM ATM M3YMN0_MUSPF M3YMN0_MUSPF MDM4 MDM4 CDK1 CDK1 RPS27A RPS27A PPP2CB PPP2CB PPP2CA PPP2CA M3YFD0_MUSPF M3YFD0_MUSPF PRDM1 PRDM1 TP53 TP53 RNF34 RNF34 AKT1 AKT1 DAXX DAXX CDK2 CDK2 PPP2R5C PPP2R5C PPP2R1B PPP2R1B USP2 USP2 PHF20 PHF20 LOC101686900 LOC101686900
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (374 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
MLST8MTOR associated protein, LST8 homolog. (328 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (182 aa)
TXNDC11Thioredoxin domain containing 11. (874 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (590 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
PRR5Proline rich 5. (389 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
M3YMN0_MUSPFUbiquitin-like domain-containing protein. (124 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (493 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PPP2CBSerine/threonine-protein phosphatase. (284 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
M3YFD0_MUSPFUncharacterized protein. (260 aa)
PRDM1PR/SET domain 1. (818 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
RNF34Ring finger protein 34. (375 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
DAXXDeath domain associated protein. (779 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (334 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (789 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (606 aa)
PHF20PHD finger protein 20. (1013 aa)
LOC101686900Ubiquitin-like domain-containing protein. (127 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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