(10 nodes) Creatine metabolism network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CKB	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (372 aa)
	SLC6A12	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (614 aa)
	CKM	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (380 aa)
	GAMT	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family. (236 aa)
	CKMT2	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
	M3YFX0_MUSPF	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
	GATM	Glycine amidinotransferase. (418 aa)
	SLC6A7	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (636 aa)
	SLC6A8	Uncharacterized protein. (520 aa)
	SLC6A11	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (633 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKB	CKM	ENSMPUP00000002333	ENSMPUP00000005998	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	0.921
CKB	CKMT2	ENSMPUP00000002333	ENSMPUP00000008219	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	0.878
CKB	GAMT	ENSMPUP00000002333	ENSMPUP00000008151	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.902
CKB	GATM	ENSMPUP00000002333	ENSMPUP00000011037	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Glycine amidinotransferase.	0.502
CKB	M3YFX0_MUSPF	ENSMPUP00000002333	ENSMPUP00000010227	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.845
CKM	CKB	ENSMPUP00000005998	ENSMPUP00000002333	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	0.921
CKM	CKMT2	ENSMPUP00000005998	ENSMPUP00000008219	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	0.875
CKM	GAMT	ENSMPUP00000005998	ENSMPUP00000008151	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.961
CKM	GATM	ENSMPUP00000005998	ENSMPUP00000011037	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	Glycine amidinotransferase.	0.586
CKM	M3YFX0_MUSPF	ENSMPUP00000005998	ENSMPUP00000010227	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.872
CKMT2	CKB	ENSMPUP00000008219	ENSMPUP00000002333	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	0.878
CKMT2	CKM	ENSMPUP00000008219	ENSMPUP00000005998	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	0.875
CKMT2	GAMT	ENSMPUP00000008219	ENSMPUP00000008151	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.955
CKMT2	GATM	ENSMPUP00000008219	ENSMPUP00000011037	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Glycine amidinotransferase.	0.665
CKMT2	M3YFX0_MUSPF	ENSMPUP00000008219	ENSMPUP00000010227	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.842
CKMT2	SLC6A8	ENSMPUP00000008219	ENSMPUP00000016041	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein.	0.428
GAMT	CKB	ENSMPUP00000008151	ENSMPUP00000002333	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	0.902
GAMT	CKM	ENSMPUP00000008151	ENSMPUP00000005998	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	0.961
GAMT	CKMT2	ENSMPUP00000008151	ENSMPUP00000008219	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.	0.955
GAMT	GATM	ENSMPUP00000008151	ENSMPUP00000011037	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Glycine amidinotransferase.	0.971