STRINGSTRING
ERCC3 ERCC3 POLR2A POLR2A POLR2E POLR2E RTF1 RTF1 ELOC ELOC CCNH CCNH G9K828_MUSPF G9K828_MUSPF LEO1 LEO1 NELFCD NELFCD TCEANC2 TCEANC2 GTF2F1 GTF2F1 MLLT1 MLLT1 MNAT1 MNAT1 NCBP1 NCBP1 ERCC2 ERCC2 POLR2I POLR2I GTF2H5 GTF2H5 EAF2 EAF2 POLR2B POLR2B CDC73 CDC73 POLR2C POLR2C PRF1 PRF1 SLC39A13 SLC39A13 NCBP2 NCBP2 M3XV89_MUSPF M3XV89_MUSPF POLR2H POLR2H CINP CINP CCNT2 CCNT2 AFF1 AFF1 EAF1 EAF1 GTF2F2 GTF2F2 GTF2H3 GTF2H3 SSRP1 SSRP1 SUPT16H SUPT16H M3Z6G7_MUSPF M3Z6G7_MUSPF M3Z5R1_MUSPF M3Z5R1_MUSPF TCEANC TCEANC NCBP2L NCBP2L PAF1 PAF1 SUPT5H SUPT5H IWS1 IWS1 POLR2D POLR2D CTDP1 CTDP1 CCNQ CCNQ MLLT3 MLLT3 TCEA3 TCEA3 ELOA ELOA ELL ELL SUPT4H1 SUPT4H1 ELOB ELOB NELFB NELFB CCNT1 CCNT1 CDK7 CDK7 M3YSQ4_MUSPF M3YSQ4_MUSPF SUPT6H SUPT6H GTF2H1 GTF2H1 CDK9 CDK9 POLR2G POLR2G POLR2F POLR2F CTR9 CTR9 AFF4 AFF4 NELFE NELFE TCEA1 TCEA1 WDR61 WDR61 NELFA NELFA AFF3 AFF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
G9K828_MUSPFSenescence downregulated leo1-like protein. (115 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (664 aa)
NELFCDNegative elongation factor complex member C/D. (575 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (220 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
MLLT1MLLT1 super elongation complex subunit. (524 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
EAF2ELL associated factor 2. (264 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
CDC73Cell division cycle 73. (531 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
PRF1Perforin 1. (602 aa)
SLC39A13Solute carrier family 39 member 13. (355 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
M3XV89_MUSPFUncharacterized protein; Belongs to the cyclin family. (501 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
CINPCyclin dependent kinase 2 interacting protein. (212 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (759 aa)
AFF1AF4/FMR2 family member 1. (1226 aa)
EAF1ELL associated factor 1. (268 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
M3Z6G7_MUSPFUncharacterized protein. (417 aa)
M3Z5R1_MUSPFUncharacterized protein. (373 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (337 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (554 aa)
SUPT5HSPT5 homolog, DSIF elongation factor subunit. (1087 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (846 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (759 aa)
CCNQCyclin Q; Belongs to the cyclin family. (250 aa)
MLLT3MLLT3 super elongation complex subunit. (464 aa)
TCEA3Transcription elongation factor A3. (350 aa)
ELOAElongin A. (816 aa)
ELLElongation factor for RNA polymerase II. (613 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (120 aa)
ELOBElongin B. (118 aa)
NELFBNegative elongation factor complex member B. (492 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (727 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (349 aa)
M3YSQ4_MUSPFGeneral transcription factor IIH subunit. (395 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
GTF2H1General transcription factor IIH subunit 1. (547 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
AFF4AF4/FMR2 family member 4. (1167 aa)
NELFENegative elongation factor complex member E. (389 aa)
TCEA1Transcription elongation factor A1. (301 aa)
WDR61WD repeat domain 61. (305 aa)
NELFANegative elongation factor complex member A. (532 aa)
AFF3AF4/FMR2 family member 3. (1217 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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