STRINGSTRING
HSCB HSCB MPP6 MPP6 PEX6 PEX6 C3orf18 C3orf18 CRAT CRAT M3YMN0_MUSPF M3YMN0_MUSPF USP9X USP9X OTC OTC HMOX1 HMOX1 M3YLQ8_MUSPF M3YLQ8_MUSPF ACBD5 ACBD5 BAG6 BAG6 TIMM17A TIMM17A M3YGY6_MUSPF M3YGY6_MUSPF M3YGD7_MUSPF M3YGD7_MUSPF RPS27A RPS27A CHCHD7 CHCHD7 M3YG80_MUSPF M3YG80_MUSPF UBE2D1 UBE2D1 GDAP1 GDAP1 M3YFD0_MUSPF M3YFD0_MUSPF CAMLG CAMLG LDHD LDHD NUDT7 NUDT7 CMC2 CMC2 CHCHD5 CHCHD5 UBL4A UBL4A FXN FXN MPP2 MPP2 LOC101681864 LOC101681864 M3Y2K4_MUSPF M3Y2K4_MUSPF G9KG26_MUSPF G9KG26_MUSPF MEST MEST M3Y103_MUSPF M3Y103_MUSPF GET3 GET3 VAPA VAPA CHCHD3 CHCHD3 TYSND1 TYSND1 EPHX4 EPHX4 BTBD8 BTBD8 C1orf146 C1orf146 M3XY79_MUSPF M3XY79_MUSPF M3XXQ2_MUSPF M3XXQ2_MUSPF TIMM8B TIMM8B M3XWC4_MUSPF M3XWC4_MUSPF ABCD3 ABCD3 ACOD1 ACOD1 CACUL1 CACUL1 M3XVN3_MUSPF M3XVN3_MUSPF M3XVH1_MUSPF M3XVH1_MUSPF CHCHD10 CHCHD10 LONP2 LONP2 ACAA1 ACAA1 PXMP2 PXMP2 DNAJC19 DNAJC19 TIMM8A TIMM8A DNAJC15 DNAJC15 SERP2 SERP2 ATP5F1B ATP5F1B FER1L6 FER1L6 APP APP M3XPE5_MUSPF M3XPE5_MUSPF M3XPE3_MUSPF M3XPE3_MUSPF PEX11B PEX11B G9KTD4_MUSPF G9KTD4_MUSPF ABCD2 ABCD2 ALDH3A2 ALDH3A2 TAZ TAZ EMD EMD UBE2D2 UBE2D2 DPY19L4 DPY19L4 GET1 GET1 ABCD1 ABCD1 PEX1 PEX1 PEX11G PEX11G OTOF OTOF M3Y9V8_MUSPF M3Y9V8_MUSPF TIMM44 TIMM44 DPY19L3 DPY19L3 DPY19L1 DPY19L1 DPY19L2 DPY19L2 M3Y8V3_MUSPF M3Y8V3_MUSPF NUDT19 NUDT19 HSDL2 HSDL2 PEX10 PEX10 SPIRE2 SPIRE2 NRDC NRDC TIMM13 TIMM13 SGTA SGTA M3Y4W5_MUSPF M3Y4W5_MUSPF DHRS2 DHRS2 M3Y4L7_MUSPF M3Y4L7_MUSPF M3YDD5_MUSPF M3YDD5_MUSPF M3Y4I9_MUSPF M3Y4I9_MUSPF LONP1 LONP1 PEX16 PEX16 UBL4B UBL4B M3Z7H2_MUSPF M3Z7H2_MUSPF SCP2D1 SCP2D1 PRNP PRNP LOC101686900 LOC101686900 M3Z4V7_MUSPF M3Z4V7_MUSPF M3Z444_MUSPF M3Z444_MUSPF G9KG30_MUSPF G9KG30_MUSPF FAM185A FAM185A SEC61G SEC61G SUGCT SUGCT TUBA8 TUBA8 PEX26 PEX26 PEX3 PEX3 GET4 GET4 PXMP4 PXMP4 M3Z270_MUSPF M3Z270_MUSPF ECH1 ECH1 TIMM50 TIMM50 GDAP1L1 GDAP1L1 M3Z0P1_MUSPF M3Z0P1_MUSPF M3Z0K2_MUSPF M3Z0K2_MUSPF PEX5L PEX5L ATAD1 ATAD1 M3YZU4_MUSPF M3YZU4_MUSPF PEX5 PEX5 CYB5A CYB5A TIMM21 TIMM21 BCS1L BCS1L PEX14 PEX14 SLC25A17 SLC25A17 PITRM1 PITRM1 ILVBL ILVBL EPHX3 EPHX3 STX1A STX1A FIS1 FIS1 CLDN15 CLDN15 MPV17L2 MPV17L2 KXD1 KXD1 GFER GFER UBA52 UBA52 M3YV71_MUSPF M3YV71_MUSPF M3YUY2_MUSPF M3YUY2_MUSPF AMACR AMACR PAM16 PAM16 PEX12 PEX12 PEX7 PEX7 TTC33 TTC33 SGTB SGTB COQ2 COQ2 NOS2 NOS2 MPV17L MPV17L GRPEL2 GRPEL2 AGPS AGPS UBE2J2 UBE2J2 C1QTNF12 C1QTNF12 MTX2 MTX2 M3YR89_MUSPF M3YR89_MUSPF TIMM22 TIMM22 TIMM17B TIMM17B STX5 STX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (279 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (554 aa)
PEX6Peroxisomal biogenesis factor 6. (965 aa)
C3orf18Chromosome 3 open reading frame 18. (162 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
M3YMN0_MUSPFUbiquitin-like domain-containing protein. (124 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
M3YLQ8_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (495 aa)
ACBD5Acyl-CoA binding domain containing 5. (542 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
TIMM17AMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (174 aa)
M3YGY6_MUSPFAmino_oxidase domain-containing protein. (388 aa)
M3YGD7_MUSPFGrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (231 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
CHCHD7Coiled-coil-helix-coiled-coil-helix domain containing 7. (85 aa)
M3YG80_MUSPFPeroxin-13_N domain-containing protein. (384 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
M3YFD0_MUSPFUncharacterized protein. (260 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
LDHDLactate dehydrogenase D. (504 aa)
NUDT7Nudix hydrolase 7. (221 aa)
CMC2COX assembly mitochondrial protein. (163 aa)
CHCHD5Coiled-coil-helix-coiled-coil-helix domain containing 5. (109 aa)
UBL4AUbiquitin like 4A. (154 aa)
FXNFrataxin. (155 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (585 aa)
LOC101681864Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (209 aa)
M3Y2K4_MUSPFzf-Tim10_DDP domain-containing protein. (102 aa)
G9KG26_MUSPFPeroxisomal bioproteinis factor 13. (403 aa)
MESTMesoderm specific transcript. (335 aa)
M3Y103_MUSPFPex2_Pex12 domain-containing protein. (295 aa)
GET3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)
VAPAVAMP associated protein A. (249 aa)
CHCHD3MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (221 aa)
TYSND1Trypsin domain containing 1. (631 aa)
EPHX4Epoxide hydrolase 4. (300 aa)
BTBD8BTB domain containing 8. (1406 aa)
C1orf146Chromosome 1 open reading frame 146. (181 aa)
M3XY79_MUSPFNudix hydrolase domain-containing protein. (231 aa)
M3XXQ2_MUSPFBile_Hydr_Trans domain-containing protein. (263 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (83 aa)
M3XWC4_MUSPFUncharacterized protein. (133 aa)
ABCD3ATP binding cassette subfamily D member 3. (660 aa)
ACOD1Aconitate decarboxylase 1. (471 aa)
CACUL1CDK2 associated cullin domain 1; Belongs to the cullin family. (371 aa)
M3XVN3_MUSPFUncharacterized protein; Belongs to the TCP-1 chaperonin family. (357 aa)
M3XVH1_MUSPFUncharacterized protein. (102 aa)
CHCHD10Coiled-coil-helix-coiled-coil-helix domain containing 10. (138 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
PXMP2Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (197 aa)
DNAJC19DnaJ heat shock protein family (Hsp40) member C19. (116 aa)
TIMM8ATranslocase of inner mitochondrial membrane 8A; Belongs to the small Tim family. (97 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (149 aa)
SERP2Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (71 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
FER1L6Fer-1 like family member 6. (1734 aa)
APPAmyloid beta precursor protein. (630 aa)
M3XPE5_MUSPFUncharacterized protein. (385 aa)
M3XPE3_MUSPFUncharacterized protein. (338 aa)
PEX11BPeroxisomal bioproteinis factor 11 beta. (259 aa)
G9KTD4_MUSPFTranslocase of inner mitochondrial membrane 10-like protein. (90 aa)
ABCD2ATP binding cassette subfamily D member 2. (742 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (293 aa)
EMDEmerin. (260 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
DPY19L4Dpy-19 like 4. (670 aa)
GET1Guided entry of tail-anchored proteins factor 1. (174 aa)
ABCD1ATP binding cassette subfamily D member 1. (733 aa)
PEX1Peroxisomal biogenesis factor 1. (1268 aa)
PEX11GPeroxisomal biogenesis factor 11 gamma. (245 aa)
OTOFOtoferlin. (2000 aa)
M3Y9V8_MUSPFV-SNARE coiled-coil homology domain-containing protein. (119 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (454 aa)
DPY19L3Dpy-19 like C-mannosyltransferase 3. (716 aa)
DPY19L1Dpy-19 like C-mannosyltransferase 1. (618 aa)
DPY19L2Dpy-19 like 2. (771 aa)
M3Y8V3_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (575 aa)
NUDT19Nudix hydrolase 19. (372 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (418 aa)
PEX10Peroxisomal biogenesis factor 10. (310 aa)
SPIRE2Spire type actin nucleation factor 2. (640 aa)
NRDCNardilysin convertase; Belongs to the peptidase M16 family. (1164 aa)
TIMM13Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
M3Y4W5_MUSPFCHCH domain-containing protein. (160 aa)
DHRS2Dehydrogenase/reductase 2. (281 aa)
M3Y4L7_MUSPFUncharacterized protein. (284 aa)
M3YDD5_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (494 aa)
M3Y4I9_MUSPFUncharacterized protein. (279 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (965 aa)
PEX16Peroxisomal membrane protein PEX16. (337 aa)
UBL4BUbiquitin like 4B. (152 aa)
M3Z7H2_MUSPFzf-Tim10_DDP domain-containing protein. (89 aa)
SCP2D1SCP2 sterol binding domain containing 1. (156 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (257 aa)
LOC101686900Ubiquitin-like domain-containing protein. (127 aa)
M3Z4V7_MUSPFzf-Tim10_DDP domain-containing protein. (90 aa)
M3Z444_MUSPFGrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (216 aa)
G9KG30_MUSPFPeroxisomal membrane protein 3, 35kDa. (305 aa)
FAM185AFamily with sequence similarity 185 member A. (378 aa)
SEC61GSEC61 translocon gamma subunit. (119 aa)
SUGCTSuccinyl-CoA:glutarate-CoA transferase. (373 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
PEX26Peroxisomal biogenesis factor 26. (311 aa)
PEX3Peroxisomal biogenesis factor 3. (316 aa)
GET4Guided entry of tail-anchored proteins factor 4. (280 aa)
PXMP4Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
M3Z270_MUSPFUncharacterized protein. (1996 aa)
ECH1Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
GDAP1L1Ganglioside induced differentiation associated protein 1 like 1. (367 aa)
M3Z0P1_MUSPFCHCH domain-containing protein. (140 aa)
M3Z0K2_MUSPFUncharacterized protein. (98 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (624 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
M3YZU4_MUSPFNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
PEX5Peroxisomal biogenesis factor 5. (640 aa)
CYB5ACytochrome b5 type A. (127 aa)
TIMM21Translocase of inner mitochondrial membrane 21. (243 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
PEX14Peroxisomal biogenesis factor 14. (374 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
PITRM1Pitrilysin metallopeptidase 1. (1036 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa)
EPHX3Epoxide hydrolase 3. (418 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (259 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (234 aa)
MPV17L2MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (206 aa)
KXD1KxDL motif containing 1. (182 aa)
GFERSulfhydryl oxidase. (206 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
M3YV71_MUSPFATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (137 aa)
M3YUY2_MUSPFUncharacterized protein. (181 aa)
AMACRAlpha-methylacyl-CoA racemase. (382 aa)
PAM16Presequence translocase associated motor 16. (125 aa)
PEX12Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
TTC33Tetratricopeptide repeat domain 33. (262 aa)
SGTBSmall glutamine rich tetratricopeptide repeat containing beta. (304 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (288 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
MPV17LUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (158 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (259 aa)
AGPSAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (566 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (259 aa)
C1QTNF12C1q and TNF related 12. (305 aa)
MTX2Metaxin 2. (266 aa)
M3YR89_MUSPFUncharacterized protein. (299 aa)
TIMM22Translocase of inner mitochondrial membrane 22. (194 aa)
TIMM17BMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (355 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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