(68 nodes) GABA receptor activation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GABRB2	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
	KCNJ16	Potassium voltage-gated channel subfamily J member 16. (419 aa)
	KCNJ2	Potassium voltage-gated channel subfamily J member 2. (427 aa)
	KCNJ10	Potassium voltage-gated channel subfamily J member 10. (379 aa)
	M3Z6U4_MUSPF	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	M3Z6N3_MUSPF	Uncharacterized protein. (428 aa)
	ENSMPUP00000018988	annotation not available (68 aa)
	KCNJ15	Potassium voltage-gated channel subfamily J member 15. (375 aa)
	ENSMPUP00000018887	annotation not available (68 aa)
	GNAT3	G protein subunit alpha transducin 3. (355 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
	NPTN	Neuroplastin. (398 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	GNB3	G protein subunit beta 3. (344 aa)
	GNB2	G protein subunit beta 2. (340 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	M3YT30_MUSPF	WD_REPEATS_REGION domain-containing protein. (153 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
	GABRA6	Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
	GABRA1	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	GABRG2	Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
	KCNJ9	Potassium voltage-gated channel subfamily J member 9. (366 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	KCNJ4	Potassium voltage-gated channel subfamily J member 4. (428 aa)
	GABRP	Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
	M3YLF8_MUSPF	Neur_chan_memb domain-containing protein. (162 aa)
	M3YLB7_MUSPF	Uncharacterized protein. (417 aa)
	GPR158	G protein-coupled receptor 158. (1197 aa)
	GABRQ	Gamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (645 aa)
	GABRA3	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
	GABRE	Gamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (494 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (562 aa)
	GABRR1	Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (461 aa)
	GABRR2	Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (490 aa)
	KCNJ5	Potassium voltage-gated channel subfamily J member 5. (419 aa)
	KCNJ6	Potassium voltage-gated channel subfamily J member 6. (423 aa)
	GPR156	G protein-coupled receptor 156. (810 aa)
	GABRD	Gamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (370 aa)
	GNB5	G protein subunit beta 5. (301 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (872 aa)
	ADCY2	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
	M3Y6E5_MUSPF	WD_REPEATS_REGION domain-containing protein. (105 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (883 aa)
	M3Z5X6_MUSPF	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
	GABRB1	Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
	GABRA4	Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (551 aa)
	GABRA2	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
	GABRG1	Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
	M3Y070_MUSPF	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	GNAL	G protein subunit alpha L. (380 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	SYNE3	Spectrin repeat containing nuclear envelope family member 3. (984 aa)
	GABRR3	Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (470 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	M3XNP5_MUSPF	Uncharacterized protein. (97 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	GABRB3	Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (501 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSMPUP00000018070	ENSMPUP00000007102	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.572
ADCY1	ADCY3	ENSMPUP00000018070	ENSMPUP00000013920	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.833
ADCY1	ADCY4	ENSMPUP00000018070	ENSMPUP00000005626	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.564
ADCY1	ADCY5	ENSMPUP00000018070	ENSMPUP00000004470	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.548
ADCY1	ADCY6	ENSMPUP00000018070	ENSMPUP00000014639	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.550
ADCY1	ADCY7	ENSMPUP00000018070	ENSMPUP00000003122	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.655
ADCY1	ADCY8	ENSMPUP00000018070	ENSMPUP00000001384	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.855
ADCY1	ADCY9	ENSMPUP00000018070	ENSMPUP00000014921	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.620
ADCY1	ENSMPUP00000018887	ENSMPUP00000018070	ENSMPUP00000018887	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.748
ADCY1	ENSMPUP00000018988	ENSMPUP00000018070	ENSMPUP00000018988	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.748
ADCY1	GNAI1	ENSMPUP00000018070	ENSMPUP00000018173	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.822
ADCY1	GNAI2	ENSMPUP00000018070	ENSMPUP00000013014	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.822
ADCY1	GNAI3	ENSMPUP00000018070	ENSMPUP00000003264	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.822
ADCY1	GNAL	ENSMPUP00000018070	ENSMPUP00000004509	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.905
ADCY1	GNAT3	ENSMPUP00000018070	ENSMPUP00000018174	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha transducin 3.	0.596
ADCY1	GNB2	ENSMPUP00000018070	ENSMPUP00000015595	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 2.	0.895
ADCY1	GNB3	ENSMPUP00000018070	ENSMPUP00000016678	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.857
ADCY1	GNB4	ENSMPUP00000018070	ENSMPUP00000017103	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 4.	0.874
ADCY1	GNB5	ENSMPUP00000018070	ENSMPUP00000007579	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.857
ADCY1	GNG11	ENSMPUP00000018070	ENSMPUP00000001628	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.863