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SCN1A SCN1A SCN9A SCN9A SCN7A SCN7A HVCN1 HVCN1 PKD2 PKD2 TRPM8 TRPM8 ITPR3 ITPR3 M3XTT1_MUSPF M3XTT1_MUSPF M3XTT7_MUSPF M3XTT7_MUSPF SCN10A SCN10A SCN5A SCN5A TPCN1 TPCN1 TRPM4 TRPM4 CACNA1A CACNA1A TRPV4 TRPV4 TRPC5 TRPC5 TPCN2 TPCN2 TRPM5 TRPM5 KCNV2 KCNV2 CNGA1 CNGA1 HCN3 HCN3 CNGA4 CNGA4 M3Y3B6_MUSPF M3Y3B6_MUSPF KCND2 KCND2 TRPM7 TRPM7 SCN8A SCN8A RYR3 RYR3 M3YAI1_MUSPF M3YAI1_MUSPF TRPV6 TRPV6 TRPM6 TRPM6 TRPM3 TRPM3 M3YD19_MUSPF M3YD19_MUSPF M3YDV1_MUSPF M3YDV1_MUSPF PKD2L2 PKD2L2 HCN2 HCN2 TRPV2 TRPV2 TRPM2 TRPM2 TRPA1 TRPA1 ITPR2 ITPR2 M3YG43_MUSPF M3YG43_MUSPF CATSPER2 CATSPER2 CACNA1S CACNA1S TRPM1 TRPM1 CNGA3 CNGA3 NALCN NALCN CACNA1E CACNA1E CNGA2 CNGA2 TRPC1 TRPC1 RYR2 RYR2 CACNA1I CACNA1I CACNA1F CACNA1F HCN1 HCN1 SCN4A SCN4A TRPC4 TRPC4 CACNA1B CACNA1B CACNA1G CACNA1G CATSPER4 CATSPER4 CACNA1H CACNA1H CACNA1D CACNA1D PKD2L1 PKD2L1 ITPR1 ITPR1 HCN4 HCN4 RYR1 RYR1 CACNA1C CACNA1C SCN3A SCN3A SCN2A SCN2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1938 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1989 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1685 aa)
HVCN1Hydrogen voltage gated channel 1. (271 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
M3XTT1_MUSPFUncharacterized protein. (1131 aa)
M3XTT7_MUSPFSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (460 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1954 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
TPCN1Two pore segment channel 1. (861 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1211 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2496 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
TPCN2Uncharacterized protein. (746 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1152 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (419 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (658 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (781 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (571 aa)
M3Y3B6_MUSPFIon_trans domain-containing protein. (188 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in rodent heart. Mediates the major part of the dendritic A-type current I(SA) in brain neurons (By similarity). This current is activated at membrane potentials that are below the threshold for action potentials. It regulates neuronal excitability, prolongs the latency before the first spike in a series of action potentials, regulates the frequency of repetitive action potential firing, shortens t [...] (399 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1738 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
RYR3Ryanodine receptor 3. (4863 aa)
M3YAI1_MUSPFANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (735 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2031 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1673 aa)
M3YD19_MUSPFUncharacterized protein. (829 aa)
M3YDV1_MUSPFUncharacterized protein. (2446 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (624 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (763 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (766 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1496 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
M3YG43_MUSPFIon_trans domain-containing protein. (166 aa)
CATSPER2Cation channel sperm associated 2. (533 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1795 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1635 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (729 aa)
NALCNSodium leak channel, non-selective. (1737 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2463 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
RYR2Ryanodine receptor 2. (4966 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2024 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1986 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (1042 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1840 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (1971 aa)
CACNA1GCalcium voltage-gated channel subunit alpha1 G. (2177 aa)
CATSPER4Cation channel sperm associated 4. (449 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2143 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2217 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (796 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (987 aa)
RYR1Ryanodine receptor 1. (4983 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1479 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1924 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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