(8 nodes) (2011) Feline coronavirus in multicat environments. network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M3Y0H1_MUSPF	Aspartate aminotransferase. (430 aa)
	ALB	Albumin. (608 aa)
	IL10	Interleukin 10. (220 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	IL6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
	CD4	CD4. (462 aa)
	GOT1	Aspartate aminotransferase. (390 aa)
	IFNB1	Interferon beta. (186 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CD4	ENSMPUP00000009221	ENSMPUP00000016704	Albumin.	CD4.	0.774
ALB	GOT1	ENSMPUP00000009221	ENSMPUP00000016891	Albumin.	Aspartate aminotransferase.	0.928
ALB	IL10	ENSMPUP00000009221	ENSMPUP00000009891	Albumin.	Interleukin 10.	0.760
ALB	IL6	ENSMPUP00000009221	ENSMPUP00000013489	Albumin.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.781
ALB	M3Y0H1_MUSPF	ENSMPUP00000009221	ENSMPUP00000004822	Albumin.	Aspartate aminotransferase.	0.811
ALB	TNF	ENSMPUP00000009221	ENSMPUP00000011297	Albumin.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.767
CD4	ALB	ENSMPUP00000016704	ENSMPUP00000009221	CD4.	Albumin.	0.774
CD4	IFNB1	ENSMPUP00000016704	ENSMPUP00000019400	CD4.	Interferon beta.	0.574
CD4	IL10	ENSMPUP00000016704	ENSMPUP00000009891	CD4.	Interleukin 10.	0.881
CD4	IL6	ENSMPUP00000016704	ENSMPUP00000013489	CD4.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.881
CD4	TNF	ENSMPUP00000016704	ENSMPUP00000011297	CD4.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.858
GOT1	ALB	ENSMPUP00000016891	ENSMPUP00000009221	Aspartate aminotransferase.	Albumin.	0.928
GOT1	IL10	ENSMPUP00000016891	ENSMPUP00000009891	Aspartate aminotransferase.	Interleukin 10.	0.567
GOT1	IL6	ENSMPUP00000016891	ENSMPUP00000013489	Aspartate aminotransferase.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.774
GOT1	M3Y0H1_MUSPF	ENSMPUP00000016891	ENSMPUP00000004822	Aspartate aminotransferase.	Aspartate aminotransferase.	0.919
GOT1	TNF	ENSMPUP00000016891	ENSMPUP00000011297	Aspartate aminotransferase.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.525
IFNB1	CD4	ENSMPUP00000019400	ENSMPUP00000016704	Interferon beta.	CD4.	0.574
IFNB1	IL10	ENSMPUP00000019400	ENSMPUP00000009891	Interferon beta.	Interleukin 10.	0.653
IFNB1	IL6	ENSMPUP00000019400	ENSMPUP00000013489	Interferon beta.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.954
IFNB1	TNF	ENSMPUP00000019400	ENSMPUP00000011297	Interferon beta.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.653