(5 nodes) (2012) Morbillivirus receptors and tropism: multiple pathways for infection. network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	FLII	FLII actin remodeling protein. (1273 aa)
	IL10	Interleukin 10. (220 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	CD4	CD4. (462 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	IL10	ENSMPUP00000016704	ENSMPUP00000009891	CD4.	Interleukin 10.	0.881
CD4	IL4	ENSMPUP00000016704	ENSMPUP00000010424	CD4.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.870
CD4	TNF	ENSMPUP00000016704	ENSMPUP00000011297	CD4.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.858
IL10	CD4	ENSMPUP00000009891	ENSMPUP00000016704	Interleukin 10.	CD4.	0.881
IL10	IL4	ENSMPUP00000009891	ENSMPUP00000010424	Interleukin 10.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.994
IL10	TNF	ENSMPUP00000009891	ENSMPUP00000011297	Interleukin 10.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.936
IL4	CD4	ENSMPUP00000010424	ENSMPUP00000016704	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	CD4.	0.870
IL4	IL10	ENSMPUP00000010424	ENSMPUP00000009891	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Interleukin 10.	0.994
IL4	TNF	ENSMPUP00000010424	ENSMPUP00000011297	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.905
TNF	CD4	ENSMPUP00000011297	ENSMPUP00000016704	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	CD4.	0.858
TNF	IL10	ENSMPUP00000011297	ENSMPUP00000009891	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	Interleukin 10.	0.936
TNF	IL4	ENSMPUP00000011297	ENSMPUP00000010424	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.905