STRINGSTRING
GIP GIP DPP4 DPP4 GCG GCG GPX5 GPX5 GPX6 GPX6 INS INS GPX7 GPX7 CFTR CFTR GPX8 GPX8 GPX3 GPX3 GPX1 GPX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GIPGastric inhibitory polypeptide. (144 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (765 aa)
GCGGlucagon. (180 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (153 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (261 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (226 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (154 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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