16 items (Mustela putorius) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	RPLP0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
	TRPV2	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (766 aa)
	LHX8	LIM homeobox 8. (377 aa)
	TMEM26	Transmembrane protein 26. (368 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1. (770 aa)
	UCP1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
	CIDEA	Cell death inducing DFFA like effector a. (219 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (201 aa)
	PRDM16	PR/SET domain 16. (1158 aa)
	TBP	TATA-box binding protein. (323 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	CIDEA	ENSMPUP00000003314	ENSMPUP00000004476	Adiponectin, C1Q and collagen domain containing.	Cell death inducing DFFA like effector a.	0.658
ADIPOQ	CITED1	ENSMPUP00000003314	ENSMPUP00000005298	Adiponectin, C1Q and collagen domain containing.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	0.422
ADIPOQ	FABP4	ENSMPUP00000003314	ENSMPUP00000001787	Adiponectin, C1Q and collagen domain containing.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.967
ADIPOQ	INS	ENSMPUP00000003314	ENSMPUP00000005593	Adiponectin, C1Q and collagen domain containing.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.771
ADIPOQ	LEP	ENSMPUP00000003314	ENSMPUP00000006474	Adiponectin, C1Q and collagen domain containing.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.903
ADIPOQ	PPARG	ENSMPUP00000003314	ENSMPUP00000017072	Adiponectin, C1Q and collagen domain containing.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.818
ADIPOQ	PRDM16	ENSMPUP00000003314	ENSMPUP00000007423	Adiponectin, C1Q and collagen domain containing.	PR/SET domain 16.	0.641
ADIPOQ	TMEM26	ENSMPUP00000003314	ENSMPUP00000010975	Adiponectin, C1Q and collagen domain containing.	Transmembrane protein 26.	0.432
ADIPOQ	UCP1	ENSMPUP00000003314	ENSMPUP00000015996	Adiponectin, C1Q and collagen domain containing.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.536
CIDEA	ADIPOQ	ENSMPUP00000004476	ENSMPUP00000003314	Cell death inducing DFFA like effector a.	Adiponectin, C1Q and collagen domain containing.	0.658
CIDEA	CITED1	ENSMPUP00000004476	ENSMPUP00000005298	Cell death inducing DFFA like effector a.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	0.410
CIDEA	FABP4	ENSMPUP00000004476	ENSMPUP00000001787	Cell death inducing DFFA like effector a.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.579
CIDEA	INS	ENSMPUP00000004476	ENSMPUP00000005593	Cell death inducing DFFA like effector a.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.511
CIDEA	LEP	ENSMPUP00000004476	ENSMPUP00000006474	Cell death inducing DFFA like effector a.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.584
CIDEA	PPARG	ENSMPUP00000004476	ENSMPUP00000017072	Cell death inducing DFFA like effector a.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.614
CIDEA	PRDM16	ENSMPUP00000004476	ENSMPUP00000007423	Cell death inducing DFFA like effector a.	PR/SET domain 16.	0.803
CIDEA	TMEM26	ENSMPUP00000004476	ENSMPUP00000010975	Cell death inducing DFFA like effector a.	Transmembrane protein 26.	0.676
CIDEA	UCP1	ENSMPUP00000004476	ENSMPUP00000015996	Cell death inducing DFFA like effector a.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.607
CITED1	ADIPOQ	ENSMPUP00000005298	ENSMPUP00000003314	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Adiponectin, C1Q and collagen domain containing.	0.422
CITED1	CIDEA	ENSMPUP00000005298	ENSMPUP00000004476	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Cell death inducing DFFA like effector a.	0.410