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TIGIT | T cell immunoreceptor with Ig and ITIM domains. (245 aa) | ||||
IRAK4 | Interleukin-1 receptor-associated kinase 4. (460 aa) | ||||
NLRX1 | NLR family member X1. (975 aa) | ||||
ATG14 | Autophagy related 14. (467 aa) | ||||
APOE | Apolipoprotein E. (322 aa) | ||||
TNFSF14 | TNF superfamily member 14; Belongs to the tumor necrosis factor family. (241 aa) | ||||
IL6R | Interleukin 6 receptor. (436 aa) | ||||
IL11 | Interleukin 11. (197 aa) | ||||
IRF4 | Interferon regulatory factor 4. (451 aa) | ||||
CXCL11 | C-X-C motif chemokine. (132 aa) | ||||
CXCL10 | C-X-C motif chemokine. (98 aa) | ||||
MAVS | Mitochondrial antiviral signaling protein. (524 aa) | ||||
TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (531 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (696 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa) | ||||
AREG | Amphiregulin. (283 aa) | ||||
ICOS | Inducible T-cell co-stimulator. (209 aa) | ||||
GNLY | Saposin B-type domain-containing protein. (163 aa) | ||||
ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) | ||||
IL10 | Interleukin 10. (220 aa) | ||||
IL7 | Interleukin 7. (158 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa) | ||||
KRT19 | Keratin 19; Belongs to the intermediate filament family. (404 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (764 aa) | ||||
LTB | Lymphotoxin beta; Belongs to the tumor necrosis factor family. (247 aa) | ||||
TNF | Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa) | ||||
RNASEL | Ribonuclease L. (726 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1153 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) | ||||
RNF41 | Ring finger protein 41. (317 aa) | ||||
CCL20 | C-C motif chemokine. (97 aa) | ||||
CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) | ||||
NCR1 | Natural cytotoxicity triggering receptor 1. (281 aa) | ||||
SPP1 | Secreted phosphoprotein 1. (272 aa) | ||||
ECSIT | ECSIT signalling integrator. (436 aa) | ||||
CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (970 aa) | ||||
IRF3 | Interferon regulatory factor 3. (421 aa) | ||||
OAS1 | 2'-5'-oligoadenylate synthetase 1. (400 aa) | ||||
OAS3 | 2'-5'-oligoadenylate synthetase 3. (1230 aa) | ||||
TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1083 aa) | ||||
TLR8 | Toll like receptor 8; Belongs to the Toll-like receptor family. (1087 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
BCR | BCR activator of RhoGEF and GTPase. (1279 aa) | ||||
CD34 | CD34 molecule. (385 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
CGAS | Cyclic GMP-AMP synthase. (526 aa) | ||||
TMPRSS4 | Transmembrane serine protease 4; Belongs to the peptidase S1 family. (436 aa) | ||||
CCL19 | C-C motif chemokine. (108 aa) | ||||
CCL21 | SCY domain-containing protein. (137 aa) | ||||
M3Y0H1_MUSPF | Aspartate aminotransferase. (430 aa) | ||||
CD274 | CD274 molecule. (303 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1130 aa) | ||||
TLE3 | TLE family member 3, transcriptional corepressor. (769 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (788 aa) | ||||
IL22 | Interleukin 22. (178 aa) | ||||
TBK1 | TANK-binding kinase 1. (729 aa) | ||||
CD40 | CD40 molecule. (277 aa) | ||||
S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) | ||||
CCR8 | C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (355 aa) | ||||
IFNG-2 | Uncharacterized protein. (187 aa) | ||||
IFNB1 | Interferon beta. (186 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) | ||||
CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa) | ||||
TLE1 | TLE family member 1, transcriptional corepressor. (771 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) | ||||
HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa) | ||||
TLE4 | TLE family member 4, transcriptional corepressor. (711 aa) | ||||
CD19 | CD19 molecule. (560 aa) | ||||
OSM | Oncostatin M. (238 aa) | ||||
SPHK1 | Sphingosine kinase 1. (386 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa) | ||||
ISG15 | ISG15 ubiquitin like modifier. (184 aa) | ||||
TAOK1 | TAO kinase 1. (1001 aa) | ||||
FOXP3 | Forkhead box P3. (433 aa) | ||||
MAP1B | Microtubule associated protein 1B. (2471 aa) | ||||
ARG1 | Arginase. (322 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) | ||||
TNFAIP3 | TNF alpha induced protein 3. (790 aa) | ||||
CCL5 | C-C motif chemokine. (91 aa) | ||||
ACE | Angiotensin-converting enzyme. (1247 aa) | ||||
CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (337 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (275 aa) | ||||
FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (796 aa) | ||||
C1R | Complement C1r; Belongs to the peptidase S1 family. (705 aa) | ||||
C1S | Complement C1s; Belongs to the peptidase S1 family. (695 aa) | ||||
CD4 | CD4. (462 aa) | ||||
CD27 | CD27 molecule. (263 aa) | ||||
LTBR | Lymphotoxin beta receptor. (420 aa) | ||||
VWF | Von Willebrand factor. (2814 aa) | ||||
GOT1 | Aspartate aminotransferase. (390 aa) |