STRINGSTRING
CXCR4 CXCR4 ANGPT2 ANGPT2 CD34 CD34 GZMB GZMB ANGPT1 ANGPT1 CXCL10 CXCL10 GNLY GNLY CD68 CD68 IL9 IL9 IL10 IL10 IL7 IL7 TFAM TFAM IL13 IL13 TNF TNF PDGFB PDGFB IL6 IL6 SDHAF2 SDHAF2 CD163 CD163 CD4 CD4 IL2 IL2 IL22 IL22 CD40 CD40 HGF HGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ANGPT2Angiopoietin 2. (495 aa)
CD34CD34 molecule. (385 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (258 aa)
ANGPT1Angiopoietin 1. (408 aa)
CXCL10C-X-C motif chemokine. (98 aa)
GNLYSaposin B-type domain-containing protein. (163 aa)
CD68CD68 molecule. (325 aa)
IL9Interleukin 9. (143 aa)
IL10Interleukin 10. (220 aa)
IL7Interleukin 7. (158 aa)
TFAMTranscription factor A, mitochondrial. (246 aa)
IL13Interleukin 13. (128 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
CD163CD163 molecule. (1110 aa)
CD4CD4. (462 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
IL22Interleukin 22. (178 aa)
CD40CD40 molecule. (277 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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