(79 nodes) (2022) Single-cell gene expression analysis of cryopreserved equine bronchoalveolar cells. network (Mustela putorius)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANXA2	Annexin. (344 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (223 aa)
	LTC4S	Leukotriene C4 synthase. (150 aa)
	CD83	CD83 molecule. (199 aa)
	NKG7	Natural killer cell granule protein 7. (165 aa)
	ITM2B	Integral membrane protein 2B. (266 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
	OLFM4	Olfactomedin 4. (498 aa)
	HPGDS	Hematopoietic prostaglandin D synthase. (199 aa)
	SSR3	Signal sequence receptor subunit 3. (167 aa)
	DERL3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (231 aa)
	CENPF	Centromere protein F. (3110 aa)
	NCAM1	Neural cell adhesion molecule 1. (1133 aa)
	CD3E	CD3 epsilon antigen. (186 aa)
	CD3D	CD3d molecule. (169 aa)
	CD3G	T-cell surface glycoprotein CD3 gamma chain. (180 aa)
	RGS1	Regulator of G protein signaling 1. (209 aa)
	RGS2	Regulator of G protein signaling 2. (211 aa)
	ALOX5AP	Arachidonate 5-lipoxygenase activating protein. (161 aa)
	GZMH	Granzyme H; Belongs to the peptidase S1 family. (244 aa)
	KLRB1	Killer cell lectin like receptor B1. (228 aa)
	KLRF1	Killer cell lectin like receptor F1. (234 aa)
	APOE	Apolipoprotein E. (322 aa)
	KLRD1	Killer cell lectin like receptor D1. (179 aa)
	KLRK1	Killer cell lectin like receptor K1. (191 aa)
	LTA4H	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa)
	CD79A	CD79a molecule. (235 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	GZMA	Granzyme A; Belongs to the peptidase S1 family. (260 aa)
	S100A4	Protein S100; Belongs to the S-100 family. (101 aa)
	LY6E	Lymphocyte antigen 6 family member E. (136 aa)
	IRF7	Interferon regulatory factor 7. (473 aa)
	ANXA1	Annexin. (345 aa)
	GNLY	Saposin B-type domain-containing protein. (163 aa)
	CD8B	Ig-like domain-containing protein. (209 aa)
	BANK1	B cell scaffold protein with ankyrin repeats 1. (783 aa)
	CD68	CD68 molecule. (325 aa)
	H2AZ1	Histone H2A; Belongs to the histone H2A family. (128 aa)
	JCHAIN	Joining chain of multimeric IgA and IgM. (158 aa)
	C4BPA	Uncharacterized protein. (605 aa)
	TCF7	Transcription factor 7. (339 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1298 aa)
	CTSW	Cathepsin W; Belongs to the peptidase C1 family. (379 aa)
	VIM	Vimentin; Belongs to the intermediate filament family. (466 aa)
	CD44	CD44 molecule (Indian blood group). (704 aa)
	EOMES	Eomesodermin. (669 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (803 aa)
	ITGAE	Integrin subunit alpha E; Belongs to the integrin alpha chain family. (1165 aa)
	CD5L	CD5 molecule like. (350 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	CD1D	CD1d molecule. (286 aa)
	LGALS1	Galectin. (135 aa)
	CD74	CD74 molecule. (279 aa)
	FTH1	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (234 aa)
	FOXP3	Forkhead box P3. (433 aa)
	GZMK	Granzyme K; Belongs to the peptidase S1 family. (268 aa)
	CD5	CD5 molecule. (493 aa)
	MS4A1	Membrane-spanning 4-domains, subfamily A, member 1. (297 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1511 aa)
	CSF3R	Colony stimulating factor 3 receptor. (839 aa)
	CD79B	CD79b molecule. (224 aa)
	CCL5	C-C motif chemokine. (91 aa)
	MARCKSL1	MARCKS like 1. (199 aa)
	C1QB	Complement C1q B chain. (249 aa)
	C1QC	Complement C1q C chain. (278 aa)
	IL2RA	Interleukin 2 receptor subunit alpha. (267 aa)
	FSCN1	Fascin. (493 aa)
	CD163	CD163 molecule. (1110 aa)
	CD4	CD4. (462 aa)
	LAG3	Lymphocyte activating 3. (521 aa)
	CD27	CD27 molecule. (263 aa)
	SRXN1	Sulfiredoxin. (137 aa)
	PLTP	Phospholipid transfer protein. (483 aa)
	MMP9	Matrix metallopeptidase 9. (704 aa)
	FOXP1	Forkhead box P1. (676 aa)
	CCR1	C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX5AP	LTA4H	ENSMPUP00000004521	ENSMPUP00000007019	Arachidonate 5-lipoxygenase activating protein.	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.	0.638
ALOX5AP	LTC4S	ENSMPUP00000004521	ENSMPUP00000000666	Arachidonate 5-lipoxygenase activating protein.	Leukotriene C4 synthase.	0.745
ANXA1	ANXA2	ENSMPUP00000008827	ENSMPUP00000018680	Annexin.	Annexin.	0.897
ANXA1	CD44	ENSMPUP00000008827	ENSMPUP00000011598	Annexin.	CD44 molecule (Indian blood group).	0.460
ANXA1	LGALS1	ENSMPUP00000008827	ENSMPUP00000012703	Annexin.	Galectin.	0.523
ANXA1	VIM	ENSMPUP00000008827	ENSMPUP00000011510	Annexin.	Vimentin; Belongs to the intermediate filament family.	0.596
ANXA2	ANXA1	ENSMPUP00000018680	ENSMPUP00000008827	Annexin.	Annexin.	0.897
ANXA2	LGALS1	ENSMPUP00000018680	ENSMPUP00000012703	Annexin.	Galectin.	0.430
APOE	PLTP	ENSMPUP00000006175	ENSMPUP00000017499	Apolipoprotein E.	Phospholipid transfer protein.	0.532
BANK1	CD79A	ENSMPUP00000009372	ENSMPUP00000007124	B cell scaffold protein with ankyrin repeats 1.	CD79a molecule.	0.421
BANK1	MS4A1	ENSMPUP00000009372	ENSMPUP00000014396	B cell scaffold protein with ankyrin repeats 1.	Membrane-spanning 4-domains, subfamily A, member 1.	0.437
C1QB	C1QC	ENSMPUP00000015843	ENSMPUP00000015847	Complement C1q B chain.	Complement C1q C chain.	0.998
C1QC	C1QB	ENSMPUP00000015847	ENSMPUP00000015843	Complement C1q C chain.	Complement C1q B chain.	0.998
CCL5	CCR1	ENSMPUP00000014852	ENSMPUP00000019530	C-C motif chemokine.	C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.995
CCL5	CCR7	ENSMPUP00000014852	ENSMPUP00000014564	C-C motif chemokine.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.962
CCL5	CD3D	ENSMPUP00000014852	ENSMPUP00000004442	C-C motif chemokine.	CD3d molecule.	0.463
CCL5	CD4	ENSMPUP00000014852	ENSMPUP00000016704	C-C motif chemokine.	CD4.	0.768
CCL5	CD40LG	ENSMPUP00000014852	ENSMPUP00000001876	C-C motif chemokine.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.501
CCL5	CD44	ENSMPUP00000014852	ENSMPUP00000011598	C-C motif chemokine.	CD44 molecule (Indian blood group).	0.570
CCL5	CD68	ENSMPUP00000014852	ENSMPUP00000009389	C-C motif chemokine.	CD68 molecule.	0.526