STRINGSTRING
DEF8 DEF8 TNS2 TNS2 ARHGEF28 ARHGEF28 DGKZ DGKZ DGKD DGKD ROCK1 ROCK1 PRKD1 PRKD1 PRKD2 PRKD2 ARHGEF2 ARHGEF2 M3Y0N2_MUSPF M3Y0N2_MUSPF UNC13B UNC13B DGKI DGKI BRAF BRAF ARHGAP29 ARHGAP29 PDZD8 PDZD8 DGKG DGKG STAC STAC CIT CIT KSR2 KSR2 CDC42BPB CDC42BPB STAC3 STAC3 DGKH DGKH DGKA DGKA PLEKHM3 PLEKHM3 VAV3 VAV3 STAC2 STAC2 GMIP GMIP DGKE DGKE UNC13A UNC13A CDC42BPA CDC42BPA MYO9B MYO9B PRKCQ PRKCQ TNS1 TNS1 PRKCD PRKCD M3Z041_MUSPF M3Z041_MUSPF PRKCI PRKCI RAF1 RAF1 M3Z1J0_MUSPF M3Z1J0_MUSPF RASGRP4 RASGRP4 TNS3 TNS3 LOC101682921 LOC101682921 PRKCA PRKCA RACGAP1 RACGAP1 KSR1 KSR1 DGKK DGKK DGKB DGKB CHN1 CHN1 ROCK2 ROCK2 ARAF ARAF RASGRP2 RASGRP2 CDC42BPG CDC42BPG PRKCB PRKCB VAV2 VAV2 PRKCE PRKCE DGKQ DGKQ PRKD3 PRKD3 RASGRP3 RASGRP3 KMT2C KMT2C ARHGAP45 ARHGAP45 PLEKHM1 PLEKHM1 M3YA49_MUSPF M3YA49_MUSPF PRKCZ PRKCZ VAV1 VAV1 M3Y544_MUSPF M3Y544_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DEF8Differentially expressed in FDCP 8 homolog. (460 aa)
TNS2Tensin 2. (1449 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1703 aa)
DGKZDiacylglycerol kinase. (934 aa)
DGKDDiacylglycerol kinase. (1171 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (909 aa)
M3Y0N2_MUSPFChimaerin; GTPase-activating protein for p21-rac. (494 aa)
UNC13BUnc-13 homolog B. (1598 aa)
DGKIDiacylglycerol kinase. (999 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
ARHGAP29Rho GTPase activating protein 29. (1274 aa)
PDZD8PDZ domain containing 8. (1152 aa)
DGKGDiacylglycerol kinase. (790 aa)
STACSH3 and cysteine rich domain. (330 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
KSR2Kinase suppressor of ras 2. (968 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1660 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
DGKHDiacylglycerol kinase. (1167 aa)
DGKADiacylglycerol kinase. (776 aa)
PLEKHM3Pleckstrin homology domain containing M3. (758 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
STAC2SH3 and cysteine rich domain 2. (377 aa)
GMIPGEM interacting protein. (969 aa)
DGKEDiacylglycerol kinase. (572 aa)
UNC13AUnc-13 homolog A. (1731 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1764 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TNS1Tensin 1. (1873 aa)
PRKCDProtein kinase C. (730 aa)
M3Z041_MUSPFUncharacterized protein. (1205 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (638 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
M3Z1J0_MUSPFUncharacterized protein. (1151 aa)
RASGRP4RAS guanyl releasing protein 4. (490 aa)
TNS3Tensin 3. (1560 aa)
LOC101682921Uncharacterized protein. (610 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
RACGAP1Rac GTPase activating protein 1. (631 aa)
KSR1Kinase suppressor of ras 1. (848 aa)
DGKKDiacylglycerol kinase. (1250 aa)
DGKBDiacylglycerol kinase. (802 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
ARAFV-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa)
RASGRP2RAS guanyl releasing protein 2. (659 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1449 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
VAV2Vav guanine nucleotide exchange factor 2. (834 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
DGKQDiacylglycerol kinase. (952 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
RASGRP3RAS guanyl releasing protein 3. (692 aa)
KMT2CLysine methyltransferase 2C. (4641 aa)
ARHGAP45Rho GTPase activating protein 45. (1121 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1065 aa)
M3YA49_MUSPFUncharacterized protein. (659 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
M3Y544_MUSPFProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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