ATP binding cassette subfamily C member 1.

ABC transporter domain-containing protein.

ATP binding cassette subfamily C member 1.

Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.

ATP binding cassette subfamily C member 2.

ABC transporter domain-containing protein.

ATP binding cassette subfamily C member 3.

ABC transporter domain-containing protein.

ABC transporter domain-containing protein.

ATP binding cassette subfamily C member 1.

ABC transporter domain-containing protein.

ATP binding cassette subfamily C member 2.

ABC transporter domain-containing protein.

ATP binding cassette subfamily C member 3.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Folate gamma-glutamyl hydrolase.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.

Thymidylate synthetase.

Component of inhibitor of nuclear factor kappa B kinase complex.

Inhibitor of nuclear factor kappa B kinase subunit beta.

Component of inhibitor of nuclear factor kappa B kinase complex.

Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.

Component of inhibitor of nuclear factor kappa B kinase complex.

Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.

Component of inhibitor of nuclear factor kappa B kinase complex.

Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]

Component of inhibitor of nuclear factor kappa B kinase complex.

Nuclear factor kappa B subunit 1.