STRINGSTRING
CCT5 CCT5 PFKP PFKP EXOSC10 EXOSC10 ZCCHC2 ZCCHC2 CNOT9 CNOT9 ENO2 ENO2 DCP1A DCP1A PDE12 PDE12 PPP4R2 PPP4R2 EXOSC1 EXOSC1 LSM3 LSM3 EDC3 EDC3 CNBP CNBP NUDT6 NUDT6 EXOSC9 EXOSC9 BBS10 BBS10 CNOT2 CNOT2 CCT2 CCT2 PABPC1L PABPC1L EXOSC5 EXOSC5 C19orf54 C19orf54 M3Z2J9_MUSPF M3Z2J9_MUSPF CNOT7 CNOT7 DCP1B DCP1B TOB1 TOB1 M3Z829_MUSPF M3Z829_MUSPF M3Z7H0_MUSPF M3Z7H0_MUSPF M3Z7B6_MUSPF M3Z7B6_MUSPF TOB2 TOB2 LSM3-2 LSM3-2 M3Z5Y4_MUSPF M3Z5Y4_MUSPF PABPC5 PABPC5 PPHLN1 PPHLN1 DIS3L DIS3L PFKM PFKM PPIB PPIB CNOT6 CNOT6 XRN2 XRN2 M3XQH3_MUSPF M3XQH3_MUSPF PAN2 PAN2 EXOSC8 EXOSC8 LRRC27 LRRC27 PNPT1 PNPT1 DHX36 DHX36 TENT4B TENT4B M3XVN3_MUSPF M3XVN3_MUSPF BTG4 BTG4 ENO4 ENO4 PAM PAM CNOT6L CNOT6L NUDT18 NUDT18 VPS72 VPS72 CNOT4 CNOT4 NAXE NAXE TTC37 TTC37 M3XZ67_MUSPF M3XZ67_MUSPF KIFBP KIFBP CNOT1 CNOT1 DDX6 DDX6 DIS3L2 DIS3L2 PNLDC1 PNLDC1 PAN3 PAN3 TCP1 TCP1 SLC30A6 SLC30A6 LSM5 LSM5 CWH43 CWH43 CCT4 CCT4 M3Y2V9_MUSPF M3Y2V9_MUSPF ZCCHC7 ZCCHC7 EXOSC3 EXOSC3 C1D C1D ENO1 ENO1 MKKS MKKS DCPS DCPS EDC4 EDC4 M3Y631_MUSPF M3Y631_MUSPF LSM6 LSM6 ERMARD ERMARD LSM8 LSM8 EXOSC4 EXOSC4 EXD2 EXD2 WRAP73 WRAP73 TMEM176B TMEM176B BTG1 BTG1 TENT4A TENT4A ICE1 ICE1 MTREX MTREX M3Y8B3_MUSPF M3Y8B3_MUSPF DHX29 DHX29 DDX60 DDX60 M3Y8V3_MUSPF M3Y8V3_MUSPF M3Y9R5_MUSPF M3Y9R5_MUSPF ZCCHC9 ZCCHC9 HELZ2 HELZ2 M3YAX0_MUSPF M3YAX0_MUSPF MPHOSPH6 MPHOSPH6 HSPA9 HSPA9 M3YDD5_MUSPF M3YDD5_MUSPF TMEM87B TMEM87B FAM161B FAM161B TMEM87A TMEM87A LSM1 LSM1 M3YEV5_MUSPF M3YEV5_MUSPF NUDT16 NUDT16 PFKL PFKL WRN WRN DIS3 DIS3 CNOT3 CNOT3 DHX57 DHX57 SKIV2L SKIV2L BTG3 BTG3 M3YHC1_MUSPF M3YHC1_MUSPF M3YHD3_MUSPF M3YHD3_MUSPF ENO3 ENO3 IPO8 IPO8 M3YHV8_MUSPF M3YHV8_MUSPF WDR61 WDR61 UFSP2 UFSP2 BTG2 BTG2 M3YJV4_MUSPF M3YJV4_MUSPF PLXDC2 PLXDC2 XRN1 XRN1 SLC30A7 SLC30A7 M3YLQ8_MUSPF M3YLQ8_MUSPF EXOSC2 EXOSC2 DCP2 DCP2 IPO7 IPO7 PPIC PPIC DPH1 DPH1 TOE1 TOE1 CNOT10 CNOT10 CNOT8 CNOT8 DPH2 DPH2 M3YSJ7_MUSPF M3YSJ7_MUSPF PARN PARN PATL1 PATL1 SLC30A5 SLC30A5 M3YTE7_MUSPF M3YTE7_MUSPF CCT6B CCT6B DHX30 DHX30 PLXDC1 PLXDC1 PABPC1 PABPC1 EXOSC7 EXOSC7 LSM4 LSM4 NOCT NOCT M3YXP6_MUSPF M3YXP6_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (790 aa)
EXOSC10Exosome component 10. (908 aa)
ZCCHC2Zinc finger CCHC-type containing 2. (1000 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
ENO2Enolase 2. (434 aa)
DCP1ADecapping mRNA 1A. (600 aa)
PDE12Phosphodiesterase 12. (609 aa)
PPP4R2Protein phosphatase 4 regulatory subunit 2. (412 aa)
EXOSC1Exosome component 1. (195 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (84 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
CNBPUncharacterized protein. (177 aa)
NUDT6Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (316 aa)
EXOSC9Exosome component 9. (439 aa)
BBS10Bardet-Biedl syndrome 10. (713 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (621 aa)
EXOSC5Exosome component 5. (235 aa)
C19orf54Chromosome 19 open reading frame 54. (346 aa)
M3Z2J9_MUSPFUncharacterized protein. (119 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
DCP1BDecapping mRNA 1B. (613 aa)
TOB1Transducer of ERBB2, 1. (345 aa)
M3Z829_MUSPFCCHC-type domain-containing protein. (607 aa)
M3Z7H0_MUSPFT-complex protein 1 subunit gamma. (497 aa)
M3Z7B6_MUSPFCCHC-type domain-containing protein. (353 aa)
TOB2Transducer of ERBB2, 2. (339 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (100 aa)
M3Z5Y4_MUSPFT-complex protein 1 subunit gamma; Belongs to the TCP-1 chaperonin family. (340 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
PPHLN1Periphilin 1. (365 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (580 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1039 aa)
M3XQH3_MUSPFUncharacterized protein. (522 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa)
EXOSC8Exosome component 8. (276 aa)
LRRC27Leucine rich repeat containing 27. (558 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (786 aa)
DHX36DEAH-box helicase 36. (1013 aa)
TENT4BTerminal nucleotidyltransferase 4B. (616 aa)
M3XVN3_MUSPFUncharacterized protein; Belongs to the TCP-1 chaperonin family. (357 aa)
BTG4BTG anti-proliferation factor 4. (230 aa)
ENO4Enolase 4. (624 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (963 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (524 aa)
NUDT18Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (323 aa)
VPS72Vacuolar protein sorting 72 homolog. (364 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (710 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (287 aa)
TTC37Tetratricopeptide repeat domain 37. (1336 aa)
M3XZ67_MUSPFUncharacterized protein; Belongs to the TCP-1 chaperonin family. (482 aa)
KIFBPKIF1 binding protein. (401 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2376 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (884 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (854 aa)
TCP1T-complex 1. (556 aa)
SLC30A6Solute carrier family 30 member 6. (486 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (202 aa)
CWH43Cell wall biogenesis 43 C-terminal homolog. (698 aa)
CCT4T-complex protein 1 subunit delta. (539 aa)
M3Y2V9_MUSPFUncharacterized protein. (74 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (504 aa)
EXOSC3Exosome component 3. (276 aa)
C1DC1D nuclear receptor corepressor. (141 aa)
ENO1Enolase 1. (434 aa)
MKKSMcKusick-Kaufman syndrome. (467 aa)
DCPSDecapping enzyme, scavenger. (341 aa)
EDC4Enhancer of mRNA decapping 4. (1439 aa)
M3Y631_MUSPFRRM domain-containing protein. (540 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (86 aa)
ERMARDER membrane associated RNA degradation. (682 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (233 aa)
EXOSC4Exosome component 4. (199 aa)
EXD2Exonuclease 3'-5' domain containing 2. (622 aa)
WRAP73WD repeat containing, antisense to TP73. (460 aa)
TMEM176BTransmembrane protein 176B. (271 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
TENT4ATerminal nucleotidyltransferase 4A. (542 aa)
ICE1Interactor of little elongation complex ELL subunit 1. (2186 aa)
MTREXMtr4 exosome RNA helicase. (1042 aa)
M3Y8B3_MUSPFT-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa)
DDX60DExD/H-box helicase 60. (1709 aa)
M3Y8V3_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (575 aa)
M3Y9R5_MUSPFT-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (475 aa)
ZCCHC9Zinc finger CCHC-type containing 9. (257 aa)
HELZ2Helicase with zinc finger 2. (2937 aa)
M3YAX0_MUSPFANK_REP_REGION domain-containing protein. (2575 aa)
MPHOSPH6M-phase phosphoprotein 6. (161 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
M3YDD5_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (494 aa)
TMEM87BTransmembrane protein 87B. (556 aa)
FAM161BFAM161 centrosomal protein B. (648 aa)
TMEM87ATransmembrane protein 87A. (556 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
M3YEV5_MUSPFAnti_prolifrtn domain-containing protein. (243 aa)
NUDT16Nudix hydrolase 16. (195 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
WRNWRN RecQ like helicase. (1397 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (752 aa)
DHX57DExH-box helicase 57. (1383 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
BTG3Uncharacterized protein. (252 aa)
M3YHC1_MUSPFSm domain-containing protein. (205 aa)
M3YHD3_MUSPFUncharacterized protein. (227 aa)
ENO3Enolase 3. (434 aa)
IPO8Importin 8. (1037 aa)
M3YHV8_MUSPFUncharacterized protein. (341 aa)
WDR61WD repeat domain 61. (305 aa)
UFSP2UFM1 specific peptidase 2. (469 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
M3YJV4_MUSPFUncharacterized protein. (44 aa)
PLXDC2Plexin domain containing 2. (529 aa)
XRN15'-3' exoribonuclease 1. (1706 aa)
SLC30A7Solute carrier family 30 member 7. (376 aa)
M3YLQ8_MUSPFUncharacterized protein; Belongs to the chaperonin (HSP60) family. (495 aa)
EXOSC2Exosome component 2. (293 aa)
DCP2Decapping mRNA 2. (422 aa)
IPO7Importin 7. (1038 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
DPH12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (444 aa)
TOE1Target of EGR1, exonuclease. (512 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (801 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
DPH22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa)
M3YSJ7_MUSPFPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
PARNPoly(A)-specific ribonuclease. (638 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (771 aa)
SLC30A5Solute carrier family 30 member 5. (674 aa)
M3YTE7_MUSPFUncharacterized protein. (49 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (566 aa)
DHX30DExH-box helicase 30. (1194 aa)
PLXDC1Plexin domain containing 1. (500 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (571 aa)
EXOSC7Exosome component 7. (321 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
NOCTNocturnin. (365 aa)
M3YXP6_MUSPFUncharacterized protein. (545 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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