STRINGSTRING
EGLN3 EGLN3 IFNGR2 IFNGR2 M3Z826_MUSPF M3Z826_MUSPF LOC101690244 LOC101690244 M3Z5Y9_MUSPF M3Z5Y9_MUSPF M3Z5X1_MUSPF M3Z5X1_MUSPF LOC101679751 LOC101679751 M3Z447_MUSPF M3Z447_MUSPF CAMK2B CAMK2B EGFR EGFR ANGPT4 ANGPT4 M3Z1Z2_MUSPF M3Z1Z2_MUSPF AKT2 AKT2 PLCG1 PLCG1 EGLN2 EGLN2 M3Z1K7_MUSPF M3Z1K7_MUSPF IFNG IFNG M3Z192_MUSPF M3Z192_MUSPF M3Z0Z0_MUSPF M3Z0Z0_MUSPF PIK3CA PIK3CA M3Z0D5_MUSPF M3Z0D5_MUSPF LTBR LTBR PDHB PDHB GAPDH GAPDH M3YZE0_MUSPF M3YZE0_MUSPF ENO2 ENO2 BCL2 BCL2 M3YYH4_MUSPF M3YYH4_MUSPF RBX1 RBX1 MTOR MTOR EP300 EP300 NPPA NPPA PFKFB3 PFKFB3 PFKP PFKP M3YXH1_MUSPF M3YXH1_MUSPF M3YX47_MUSPF M3YX47_MUSPF TEK TEK SERPINE1 SERPINE1 ZAN ZAN EPO EPO AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF M3YW74_MUSPF M3YW74_MUSPF ELOB ELOB LTF LTF RPS6KB1 RPS6KB1 CREBBP CREBBP ERBB2 ERBB2 M3YU12_MUSPF M3YU12_MUSPF IFNGR1 IFNGR1 PIK3R1 PIK3R1 PRKCA PRKCA M3YSQ8_MUSPF M3YSQ8_MUSPF NOS2 NOS2 ALDOC ALDOC CDKN1A CDKN1A M3YRM2_MUSPF M3YRM2_MUSPF CAMK2A CAMK2A ARSI ARSI SLC2A1 SLC2A1 M3YQQ4_MUSPF M3YQQ4_MUSPF M3YQL8_MUSPF M3YQL8_MUSPF IL6 IL6 TIMP1 TIMP1 M3YNJ8_MUSPF M3YNJ8_MUSPF VEGFA VEGFA MKNK1 MKNK1 MAPK3 MAPK3 M3YMB2_MUSPF M3YMB2_MUSPF EIF4E1B EIF4E1B CYBB CYBB XK XK HMOX1 HMOX1 HK3 HK3 PRKCB PRKCB IGF1 IGF1 RELA RELA M3YJH6_MUSPF M3YJH6_MUSPF M3YIC4_MUSPF M3YIC4_MUSPF ENO3 ENO3 IGF1R IGF1R STAT3 STAT3 ELOC ELOC PRKCG PRKCG PFKL PFKL M3YF69_MUSPF M3YF69_MUSPF EIF4EBP1 EIF4EBP1 M3YE77_MUSPF M3YE77_MUSPF TF TF M3YDL2_MUSPF M3YDL2_MUSPF NFKB1 NFKB1 PLCG2 PLCG2 PGK2 PGK2 PIK3CB PIK3CB EGF EGF INSR INSR M3YAG9_MUSPF M3YAG9_MUSPF HK2 HK2 M3YA76_MUSPF M3YA76_MUSPF NOS3 NOS3 IL6R IL6R M3Y7D6_MUSPF M3Y7D6_MUSPF MKNK2 MKNK2 ALDOB ALDOB M3Y5C5_MUSPF M3Y5C5_MUSPF HIF1A HIF1A ENO1 ENO1 PIK3CD PIK3CD M3Y3S2_MUSPF M3Y3S2_MUSPF CUL2 CUL2 ANGPT1 ANGPT1 INS INS EGLN1 EGLN1 M3Y1G8_MUSPF M3Y1G8_MUSPF M3Y027_MUSPF M3Y027_MUSPF FLT1 FLT1 M3XZF1_MUSPF M3XZF1_MUSPF HKDC1 HKDC1 M3XZD5_MUSPF M3XZD5_MUSPF HK1 HK1 ARNT ARNT TFRC TFRC RPS6KB2 RPS6KB2 M3XXB0_MUSPF M3XXB0_MUSPF ENO4 ENO4 CAMK2G CAMK2G M3XW90_MUSPF M3XW90_MUSPF PDHA1 PDHA1 MAPK1 MAPK1 ANGPT2 ANGPT2 M3XT05_MUSPF M3XT05_MUSPF AKT1 AKT1 M3XSH0_MUSPF M3XSH0_MUSPF M3XSB2_MUSPF M3XSB2_MUSPF TLR4 TLR4 M3Z8B6_MUSPF M3Z8B6_MUSPF PGK1 PGK1 G9K812_MUSPF G9K812_MUSPF MAP2K1 MAP2K1 PFKM PFKM EDN1 EDN1 PDK1 PDK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
IFNGR2Interferon gamma receptor 2. (341 aa)
M3Z826_MUSPF40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (243 aa)
LOC101690244Glyceraldehyde-3-phosphate dehydrogenase. (338 aa)
M3Z5Y9_MUSPFGlyceraldehyde-3-phosphate dehydrogenase. (332 aa)
M3Z5X1_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
LOC101679751L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
M3Z447_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (610 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
ANGPT4Angiopoietin 4. (498 aa)
M3Z1Z2_MUSPFUncharacterized protein. (2103 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (448 aa)
M3Z1K7_MUSPFL-lactate dehydrogenase. (242 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
M3Z192_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (315 aa)
M3Z0Z0_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (301 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
M3Z0D5_MUSPFUncharacterized protein. (219 aa)
LTBRLymphotoxin beta receptor. (420 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
M3YZE0_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (312 aa)
ENO2Enolase 2. (434 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
M3YYH4_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (311 aa)
RBX1Ring-box 1. (108 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
EP300E1A binding protein p300. (2425 aa)
NPPANatriuretic peptide A. (163 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (511 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (790 aa)
M3YXH1_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (300 aa)
M3YX47_MUSPFUncharacterized protein. (94 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
SERPINE1Serpin peptidase inhibitor, clade E, member 1; Belongs to the serpin family. (400 aa)
ZANZonadhesin (gene/pseudogene). (2507 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
M3YW74_MUSPFGp_dh_N domain-containing protein. (278 aa)
ELOBElongin B. (118 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CREBBPCREB binding protein. (2442 aa)
ERBB2Receptor protein-tyrosine kinase. (1260 aa)
M3YU12_MUSPFGlyceraldehyde-3-phosphate dehydrogenase. (321 aa)
IFNGR1Interferon gamma receptor 1. (474 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
M3YSQ8_MUSPFUncharacterized protein; Belongs to the LDH/MDH superfamily. (312 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
M3YRM2_MUSPFGp_dh_N domain-containing protein. (272 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (679 aa)
ARSIArylsulfatase family member I. (575 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (480 aa)
M3YQQ4_MUSPFL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (230 aa)
M3YQL8_MUSPFL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (385 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (415 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
M3YMB2_MUSPFFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (263 aa)
CYBBCytochrome b-245 beta chain. (568 aa)
XKXK-related protein. (444 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
HK3Hexokinase 3. (924 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
IGF1Insulin like growth factor 1. (153 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
M3YJH6_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (296 aa)
M3YIC4_MUSPFGp_dh_N domain-containing protein. (273 aa)
ENO3Enolase 3. (434 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
M3YF69_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (207 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
M3YE77_MUSPFUncharacterized protein; Belongs to the transferrin family. (699 aa)
TFTransferrin; Belongs to the transferrin family. (696 aa)
M3YDL2_MUSPFGp_dh_N domain-containing protein. (203 aa)
NFKB1Nuclear factor kappa B subunit 1. (971 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
PGK2Phosphoglycerate kinase. (479 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
M3YAG9_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (316 aa)
HK2Hexokinase 2. (917 aa)
M3YA76_MUSPFProtein kinase domain-containing protein. (533 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
IL6RInterleukin 6 receptor. (436 aa)
M3Y7D6_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (464 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
M3Y5C5_MUSPFUncharacterized protein; Belongs to the LDH/MDH superfamily. (293 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
ENO1Enolase 1. (434 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
M3Y3S2_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (315 aa)
CUL2Cullin 2; Belongs to the cullin family. (745 aa)
ANGPT1Angiopoietin 1. (408 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (296 aa)
M3Y1G8_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
FLT1Receptor protein-tyrosine kinase. (1338 aa)
M3XZF1_MUSPFPhosphotransferase. (133 aa)
HKDC1Hexokinase domain containing 1. (704 aa)
M3XZD5_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (297 aa)
HK1Hexokinase 1. (917 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (719 aa)
TFRCTransferrin receptor protein 1. (770 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
M3XXB0_MUSPFLdh_1_N domain-containing protein. (275 aa)
ENO4Enolase 4. (624 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (561 aa)
M3XW90_MUSPFGp_dh_N domain-containing protein. (240 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (389 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
ANGPT2Angiopoietin 2. (495 aa)
M3XT05_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (324 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
M3XSH0_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (219 aa)
M3XSB2_MUSPFGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (303 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
M3Z8B6_MUSPFUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (216 aa)
PGK1Phosphoglycerate kinase. (417 aa)
G9K812_MUSPFL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa)
EDN1Endothelin 1. (202 aa)
PDK1Protein-serine/threonine kinase. (378 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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