STRINGSTRING
ATG101 ATG101 REM2 REM2 M3Y6T5_MUSPF M3Y6T5_MUSPF EIF2S1 EIF2S1 M3Y6L7_MUSPF M3Y6L7_MUSPF RB1CC1 RB1CC1 CTSV CTSV DUS2 DUS2 STX17 STX17 ATG4D ATG4D HIF1A HIF1A GABARAPL1 GABARAPL1 PIK3CD PIK3CD RAB1A RAB1A M3Y3Y6_MUSPF M3Y3Y6_MUSPF IFITM10 IFITM10 RAB39A RAB39A M3Y3L0_MUSPF M3Y3L0_MUSPF TSSK4 TSSK4 M3Y3D0_MUSPF M3Y3D0_MUSPF M3Y3B0_MUSPF M3Y3B0_MUSPF RASL11B RASL11B ATG14 ATG14 PRKACB PRKACB CSDE1 CSDE1 M3Y2Z6_MUSPF M3Y2Z6_MUSPF INS INS AMBRA1 AMBRA1 ATG13 ATG13 ENSMPUP00000005388 ENSMPUP00000005388 ATG16L1 ATG16L1 RRAD RRAD HIF3A HIF3A RIT1 RIT1 WDR41 WDR41 NPAS1 NPAS1 SH3GLB1 SH3GLB1 M3Y027_MUSPF M3Y027_MUSPF M3XZP3_MUSPF M3XZP3_MUSPF DAPK3 DAPK3 M3XYF5_MUSPF M3XYF5_MUSPF LMLN LMLN DDIT4 DDIT4 RUBCN RUBCN IRS4 IRS4 ATG4A ATG4A RPS6KB2 RPS6KB2 RRAGB RRAGB ZFYVE1 ZFYVE1 SNAP29 SNAP29 RAB19 RAB19 MAPK1 MAPK1 PRKACA PRKACA ATG2B ATG2B M3XV19_MUSPF M3XV19_MUSPF KCNK1 KCNK1 M3XU99_MUSPF M3XU99_MUSPF RRAS RRAS TTC14 TTC14 BNIP3 BNIP3 ULK1 ULK1 AKT1S1 AKT1S1 MAPK10 MAPK10 DAPK1 DAPK1 AKT1 AKT1 M3XSF2_MUSPF M3XSF2_MUSPF HMGB2 HMGB2 CTSB CTSB SUPT20H SUPT20H LOC101681938 LOC101681938 M3XR92_MUSPF M3XR92_MUSPF RUBCNL RUBCNL LAMP2 LAMP2 NOL4 NOL4 IRS1 IRS1 M3XPU3_MUSPF M3XPU3_MUSPF DEPTOR DEPTOR M3XPN8_MUSPF M3XPN8_MUSPF NPAS3 NPAS3 PIK3C3 PIK3C3 RIT2 RIT2 SNAP47 SNAP47 ATG12 ATG12 SQSTM1 SQSTM1 DAPK2 DAPK2 MAPK9 MAPK9 TANK TANK MAP2K1 MAP2K1 M3XML9_MUSPF M3XML9_MUSPF CFLAR CFLAR ATG4B ATG4B M3XM17_MUSPF M3XM17_MUSPF M3XLW0_MUSPF M3XLW0_MUSPF SMCR8 SMCR8 M3Z8R5_MUSPF M3Z8R5_MUSPF TSSK2 TSSK2 TSSK1B TSSK1B TSSK6 TSSK6 RRAGA RRAGA HMGB4 HMGB4 ENSMPUP00000018241 ENSMPUP00000018241 REM1 REM1 BCL2L1 BCL2L1 NOL4L NOL4L TP53INP2 TP53INP2 AKT2 AKT2 TBK1 TBK1 RAB7A RAB7A RAB43 RAB43 PIK3CA PIK3CA RAF1 RAF1 ATG7 ATG7 MTMR14 MTMR14 ITPR1 ITPR1 M3YZX8_MUSPF M3YZX8_MUSPF PRKCD PRKCD WIPI2 WIPI2 M3YYR0_MUSPF M3YYR0_MUSPF BCL2 BCL2 MTOR MTOR PRKCQ PRKCQ RAB39B RAB39B RAB33B RAB33B RAB8A RAB8A C9orf72 C9orf72 PDIK1L PDIK1L AKT3 AKT3 M3YWA8_MUSPF M3YWA8_MUSPF BECN2 BECN2 M3YW64_MUSPF M3YW64_MUSPF TSC2 TSC2 MLST8 MLST8 MTMR4 MTMR4 PDPK1 PDPK1 TSSK3 TSSK3 VMP1 VMP1 RPS6KB1 RPS6KB1 M3YUJ9_MUSPF M3YUJ9_MUSPF M3YTP8_MUSPF M3YTP8_MUSPF ERN1 ERN1 PRKAA1 PRKAA1 PIK3R1 PIK3R1 RHEBL1 RHEBL1 WIPI1 WIPI1 RRAGC RRAGC ENSMPUP00000014058 ENSMPUP00000014058 KIAA1671 KIAA1671 CRYBB3 CRYBB3 MTMR3 MTMR3 PPP1R14B PPP1R14B RRAS2 RRAS2 RASEF RASEF M3YNJ8_MUSPF M3YNJ8_MUSPF BAD BAD MAPK3 MAPK3 TSC1 TSC1 ATG2A ATG2A ERN2 ERN2 RAB7B RAB7B RPTOR RPTOR TRAF6 TRAF6 M3YJK7_MUSPF M3YJK7_MUSPF M3YIA6_MUSPF M3YIA6_MUSPF NRBF2 NRBF2 ZFYVE28 ZFYVE28 IGF1R IGF1R M3YH29_MUSPF M3YH29_MUSPF GABARAP GABARAP KRAS KRAS M3YFV0_MUSPF M3YFV0_MUSPF PPP2CB PPP2CB PPP2CA PPP2CA BECN1 BECN1 LAMP1 LAMP1 GABARAPL2 GABARAPL2 ATG16L2 ATG16L2 ATG5 ATG5 STK35 STK35 DDIT4L DDIT4L EIF2AK3 EIF2AK3 RRAGD RRAGD MRAS MRAS MAPK8 MAPK8 PIK3CB PIK3CB MAP3K7 MAP3K7 VAMP8 VAMP8 GEM GEM RHEB RHEB CRYGN CRYGN UVRAG UVRAG TP53INP1 TP53INP1 STK11 STK11 EIF2AK4 EIF2AK4 ATG10 ATG10 ATG4C ATG4C ATG9B ATG9B PRKAA2 PRKAA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG101Autophagy related 101. (218 aa)
REM2RRAD and GEM like GTPase 2. (342 aa)
M3Y6T5_MUSPFAutophagy-related protein 3. (293 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
M3Y6L7_MUSPFSerine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (281 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (335 aa)
DUS2Dihydrouridine synthase 2. (493 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (443 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
GABARAPL1GABA type A receptor associated protein like 1. (123 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
RAB1ARAB1A, member RAS oncogene family. (251 aa)
M3Y3Y6_MUSPFPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (375 aa)
IFITM10Interferon induced transmembrane protein 10. (232 aa)
RAB39ARAB39A, member RAS oncogene family. (176 aa)
M3Y3L0_MUSPFUncharacterized protein. (99 aa)
TSSK4Testis specific serine kinase 4. (339 aa)
M3Y3D0_MUSPFUncharacterized protein; Belongs to the peptidase C1 family. (334 aa)
M3Y3B0_MUSPFUncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
RASL11BRAS like family 11 member B. (249 aa)
ATG14Autophagy related 14. (467 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
CSDE1Cold shock domain containing E1. (784 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1209 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
ENSMPUP00000005388annotation not available (614 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (669 aa)
RIT1Ras like without CAAX 1. (181 aa)
WDR41WD repeat domain 41. (459 aa)
NPAS1Neuronal PAS domain protein 1. (593 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
M3Y027_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
M3XYF5_MUSPFUncharacterized protein. (341 aa)
LMLNLeishmanolysin-like peptidase. (692 aa)
DDIT4DNA damage inducible transcript 4. (230 aa)
RUBCNRubicon autophagy regulator. (1019 aa)
IRS4Insulin receptor substrate 4. (1259 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
RRAGBRas related GTP binding B. (336 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (787 aa)
SNAP29Synaptosome associated protein 29. (258 aa)
RAB19RAB19, member RAS oncogene family. (217 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ATG2BAutophagy related 2B. (2078 aa)
M3XV19_MUSPFUncharacterized protein. (123 aa)
KCNK1Potassium two pore domain channel subfamily K member 1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (233 aa)
M3XU99_MUSPFUncharacterized protein. (788 aa)
RRASRAS related. (218 aa)
TTC14Tetratricopeptide repeat domain 14. (769 aa)
BNIP3BCL2 interacting protein 3. (190 aa)
ULK1Unc-51 like autophagy activating kinase 1. (970 aa)
AKT1S1AKT1 substrate 1. (285 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
M3XSF2_MUSPFUncharacterized protein. (124 aa)
HMGB2High mobility group box 2. (210 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
LOC101681938Protein kinase domain-containing protein. (490 aa)
M3XR92_MUSPFUncharacterized protein. (774 aa)
RUBCNLRubicon like autophagy enhancer. (656 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
NOL4Nucleolar protein 4. (485 aa)
IRS1Insulin receptor substrate 1. (1428 aa)
M3XPU3_MUSPFUncharacterized protein; Belongs to the protein kinase superfamily. (361 aa)
DEPTORDEP domain containing MTOR interacting protein. (279 aa)
M3XPN8_MUSPFBHLH domain-containing protein. (176 aa)
NPAS3Neuronal PAS domain protein 3. (812 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
RIT2Ras like without CAAX 2. (218 aa)
SNAP47Synaptosome associated protein 47. (415 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
SQSTM1Sequestosome 1. (371 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (396 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
TANKTRAF family member associated NFKB activator. (446 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
M3XML9_MUSPFAutophagy-related protein 3. (314 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (482 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
M3XLW0_MUSPFDUF3543 domain-containing protein. (669 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
M3Z8R5_MUSPFUncharacterized protein. (201 aa)
TSSK2Testis specific serine kinase 2; Belongs to the protein kinase superfamily. (362 aa)
TSSK1BTestis specific serine kinase 1B; Belongs to the protein kinase superfamily. (363 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa)
RRAGARas related GTP binding A. (313 aa)
HMGB4High mobility group box 4. (188 aa)
ENSMPUP00000018241annotation not available (201 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
BCL2L1BCL2 like 1. (233 aa)
NOL4LNucleolar protein 4 like. (573 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (224 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TBK1TANK-binding kinase 1. (729 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (788 aa)
MTMR14Myotubularin related protein 14. (649 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
M3YZX8_MUSPFUncharacterized protein. (144 aa)
PRKCDProtein kinase C. (730 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (436 aa)
M3YYR0_MUSPFAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
PDIK1LPDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (341 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
BECN2Beclin 2. (437 aa)
M3YW64_MUSPFUncharacterized protein. (513 aa)
TSC2TSC complex subunit 2. (1906 aa)
MLST8MTOR associated protein, LST8 homolog. (328 aa)
MTMR4Myotubularin related protein 4. (1146 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
TSSK3Testis specific serine kinase 3. (225 aa)
VMP1Vacuole membrane protein 1. (406 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
M3YTP8_MUSPFV-SNARE coiled-coil homology domain-containing protein. (122 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (975 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
RHEBL1RHEB like 1. (177 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (479 aa)
RRAGCRas related GTP binding C. (399 aa)
ENSMPUP00000014058annotation not available (213 aa)
KIAA1671KIAA1671. (1838 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
MTMR3Myotubularin related protein 3. (1211 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (145 aa)
RRAS2RAS related 2. (181 aa)
RASEFRAS and EF-hand domain containing. (555 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
BADBCL2 associated agonist of cell death. (168 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
TSC1TSC complex subunit 1. (1165 aa)
ATG2AAutophagy related 2A. (1930 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1244 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
M3YJK7_MUSPFUncharacterized protein. (201 aa)
M3YIA6_MUSPFUncharacterized protein. (333 aa)
NRBF2Nuclear receptor binding factor 2. (286 aa)
ZFYVE28Zinc finger FYVE-type containing 28. (813 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
GABARAPGABA type A receptor-associated protein. (122 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
M3YFV0_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
PPP2CBSerine/threonine-protein phosphatase. (284 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
BECN1Beclin 1. (448 aa)
LAMP1Lysosomal associated membrane protein 1. (388 aa)
GABARAPL2GABA type A receptor associated protein like 2. (120 aa)
ATG16L2Autophagy related 16 like 2. (620 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
STK35Serine/threonine kinase 35. (538 aa)
DDIT4LDNA damage inducible transcript 4 like. (167 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1065 aa)
RRAGDRas related GTP binding D. (363 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
MAPK8Mitogen-activated protein kinase. (397 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
VAMP8Vesicle associated membrane protein 8. (111 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
RHEBRas homolog, mTORC1 binding. (179 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)
UVRAGUV radiation resistance associated. (660 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (443 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1657 aa)
ATG10Autophagy related 10. (216 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (869 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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