STRINGSTRING
ADCY3 ADCY3 PRKAB2 PRKAB2 SOD1 SOD1 FOXA2 FOXA2 IRS1 IRS1 ADCY8 ADCY8 AKT1 AKT1 TIMM8A TIMM8A AKT1S1 AKT1S1 KCNK1 KCNK1 PRKAB1 PRKAB1 PRKACA PRKACA ADCY7 ADCY7 CRYAB CRYAB TIMM8B TIMM8B RPS6KB2 RPS6KB2 IRS4 IRS4 EIF4EBP2 EIF4EBP2 ADCY5 ADCY5 M3Y105_MUSPF M3Y105_MUSPF INS INS ADCY4 ADCY4 M3Y2Z6_MUSPF M3Y2Z6_MUSPF CSDE1 CSDE1 PRKACB PRKACB M3Y362_MUSPF M3Y362_MUSPF PIK3CD PIK3CD ADCY2 ADCY2 PRKAA2 PRKAA2 M3Y8D0_MUSPF M3Y8D0_MUSPF INSR INSR PRKAG2 PRKAG2 PIK3CB PIK3CB ATG5 ATG5 M3YEF8_MUSPF M3YEF8_MUSPF FOXO3 FOXO3 CLPB CLPB HDAC2 HDAC2 KRAS KRAS M3YH29_MUSPF M3YH29_MUSPF IGF1R IGF1R M3YHB9_MUSPF M3YHB9_MUSPF M3YIA6_MUSPF M3YIA6_MUSPF CAT CAT RPTOR RPTOR SIRT1 SIRT1 IGF1 IGF1 M3YM35_MUSPF M3YM35_MUSPF M3YNJ8_MUSPF M3YNJ8_MUSPF PTRHD1 PTRHD1 PRKAG1 PRKAG1 PIK3R1 PIK3R1 ADCY6 ADCY6 PRKAA1 PRKAA1 ADCY9 ADCY9 RPS6KB1 RPS6KB1 HDAC1 HDAC1 M3YW64_MUSPF M3YW64_MUSPF M3YWA8_MUSPF M3YWA8_MUSPF AKT3 AKT3 FOXA1 FOXA1 HSPA2 HSPA2 HSPA8 HSPA8 HSPA1L HSPA1L ADCY1 ADCY1 AKT2 AKT2 PIK3CA PIK3CA PRKAG3 PRKAG3 MTOR MTOR SOD3 SOD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (296 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
FOXA2Forkhead box A2. (457 aa)
IRS1Insulin receptor substrate 1. (1428 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TIMM8ATranslocase of inner mitochondrial membrane 8A; Belongs to the small Tim family. (97 aa)
AKT1S1AKT1 substrate 1. (285 aa)
KCNK1Potassium two pore domain channel subfamily K member 1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (233 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (83 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
IRS4Insulin receptor substrate 4. (1259 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
M3Y105_MUSPFSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
CSDE1Cold shock domain containing E1. (784 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
M3Y362_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (880 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
M3Y8D0_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (617 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (529 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
FOXO3Forkhead box O3. (671 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (709 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
M3YHB9_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (642 aa)
M3YIA6_MUSPFUncharacterized protein. (333 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1244 aa)
SIRT1Sirtuin 1. (557 aa)
IGF1Insulin like growth factor 1. (153 aa)
M3YM35_MUSPFUncharacterized protein; Belongs to the heat shock protein 70 family. (567 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
HDAC1Histone deacetylase 1. (482 aa)
M3YW64_MUSPFUncharacterized protein. (513 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
FOXA1Forkhead box A1. (501 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (635 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (488 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.