STRINGSTRING
THBS1 THBS1 EP300 EP300 NBL1 NBL1 M3YX09_MUSPF M3YX09_MUSPF CDKN2B CDKN2B ID3 ID3 GREM2 GREM2 ANKFN1 ANKFN1 MATN2 MATN2 RPS6KB1 RPS6KB1 BAMBI BAMBI CREBBP CREBBP SMURF2 SMURF2 M3YSK2_MUSPF M3YSK2_MUSPF FST FST M3YSB8_MUSPF M3YSB8_MUSPF RHOA RHOA LDAH LDAH GDF7 GDF7 ID2 ID2 MAPK3 MAPK3 TGFBR2 TGFBR2 LTBP3 LTBP3 FBN1 FBN1 FBN2 FBN2 FMOD FMOD TNF TNF E2F5 E2F5 PPP2CB PPP2CB PPP2CA PPP2CA LTBP1 LTBP1 PITX1 PITX1 SMAD5 SMAD5 FSTL3 FSTL3 TFDP1 TFDP1 PKNOX1 PKNOX1 LTBP2 LTBP2 TGFB3 TGFB3 BMPR1A BMPR1A INTS8 INTS8 SMAD4 SMAD4 GDF6 GDF6 PITX2 PITX2 GREM1 GREM1 RBX1 RBX1 SMURF1 SMURF1 PITX3 PITX3 THSD4 THSD4 NEO1 NEO1 PPP2R1A PPP2R1A IFNG IFNG BMP2 BMP2 SP1 SP1 AMHR2 AMHR2 E2F4 E2F4 ROCK1 ROCK1 BMP4 BMP4 TGIF1 TGIF1 ZFYVE16 ZFYVE16 ADAMTSL4 ADAMTSL4 M3XZF0_MUSPF M3XZF0_MUSPF NODAL NODAL TGFB2 TGFB2 RPS6KB2 RPS6KB2 RGMB RGMB ACVR2A ACVR2A PPP2R1B PPP2R1B MAPK1 MAPK1 CHRD CHRD BMP5 BMP5 NOG NOG M3Z5S3_MUSPF M3Z5S3_MUSPF M3Z4W8_MUSPF M3Z4W8_MUSPF INHBB INHBB INHBA INHBA ID1 ID1 GDF5 GDF5 TGIF2 TGIF2 RBL1 RBL1 LTBP4 LTBP4 TGFB1 TGFB1 MATN4 MATN4 RGMA RGMA SMAD3 SMAD3 SMAD6 SMAD6 BMPR2 BMPR2 ACVR1C ACVR1C ACVR1 ACVR1 BMP6 BMP6 HJV HJV SMAD7 SMAD7 SMAD2 SMAD2 MYC MYC INHBC INHBC SMAD9 SMAD9 BMPR1B BMPR1B ACVR2B ACVR2B PKNOX2 PKNOX2 BMP7 BMP7 TGFBR1 TGFBR1 SMAD1 SMAD1 ZFYVE9 ZFYVE9 USF2 USF2 CUL1 CUL1 FBN3 FBN3 DCN DCN ACVR1B ACVR1B SNAPIN SNAPIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THBS1Thrombospondin 1. (1170 aa)
EP300E1A binding protein p300. (2425 aa)
NBL1NBL1, DAN family BMP antagonist. (175 aa)
M3YX09_MUSPFUncharacterized protein. (126 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (131 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
GREM2Gremlin. (177 aa)
ANKFN1Ankyrin repeat and fibronectin type III domain containing 1. (1151 aa)
MATN2Matrilin 2. (816 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
CREBBPCREB binding protein. (2442 aa)
SMURF2E3 ubiquitin-protein ligase. (739 aa)
M3YSK2_MUSPFTGF_BETA_2 domain-containing protein. (291 aa)
FSTFollistatin. (344 aa)
M3YSB8_MUSPFTGF_BETA_2 domain-containing protein. (351 aa)
RHOARas homolog family member A. (193 aa)
LDAHLipid droplet associated hydrolase. (325 aa)
GDF7Growth differentiation factor 7. (382 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (445 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1186 aa)
FBN1Fibrillin 1. (2877 aa)
FBN2Fibrillin 2. (2910 aa)
FMODFibromodulin. (376 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
E2F5E2F transcription factor 5. (332 aa)
PPP2CBSerine/threonine-protein phosphatase. (284 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1573 aa)
PITX1Homeobox protein. (290 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
FSTL3Follistatin like 3. (260 aa)
TFDP1Transcription factor. (410 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1818 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
INTS8Integrator complex subunit 8. (995 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GDF6Growth differentiation factor 6. (434 aa)
PITX2Homeobox protein. (317 aa)
GREM1Gremlin. (184 aa)
RBX1Ring-box 1. (108 aa)
SMURF1E3 ubiquitin-protein ligase. (725 aa)
PITX3Homeobox protein. (314 aa)
THSD4Thrombospondin type 1 domain containing 4. (574 aa)
NEO1Neogenin 1. (1419 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (590 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SP1Sp1 transcription factor. (787 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (585 aa)
E2F4E2F transcription factor 4. (403 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TGIF1TGFB induced factor homeobox 1. (272 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1450 aa)
ADAMTSL4ADAMTS like 4. (1102 aa)
M3XZF0_MUSPFLeft-right determination factor. (367 aa)
NODALNodal growth differentiation factor. (348 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (401 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (789 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
CHRDChordin. (882 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
M3Z5S3_MUSPFHomeobox domain-containing protein. (231 aa)
M3Z4W8_MUSPFUncharacterized protein; Belongs to the SKP1 family. (163 aa)
INHBBInhibin subunit beta B. (238 aa)
INHBAInhibin subunit beta A. (424 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
GDF5Growth differentiation factor 5. (500 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
RBL1RB transcriptional corepressor like 1. (1066 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1619 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
MATN4Matrilin 4. (567 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (455 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
SMAD6Mothers against decapentaplegic homolog. (494 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
HJVHemojuvelin BMP co-receptor. (426 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD2Mothers against decapentaplegic homolog. (495 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
INHBCInhibin subunit beta C. (353 aa)
SMAD9Mothers against decapentaplegic homolog. (432 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (484 aa)
PKNOX2PBX/knotted 1 homeobox 2. (472 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
USF2Upstream transcription factor 2, c-fos interacting. (351 aa)
CUL1Cullin 1; Belongs to the cullin family. (677 aa)
FBN3Fibrillin 3. (3532 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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