STRINGSTRING
FYN FYN UNC5D UNC5D EFNA3 EFNA3 M3Y2Z6_MUSPF M3Y2Z6_MUSPF EFNA1 EFNA1 NFATC4 NFATC4 ARHGEF12 ARHGEF12 ILK ILK ROCK1 ROCK1 NGEF NGEF SEMA6B SEMA6B MYL12A MYL12A MYL12B MYL12B SEMA4A SEMA4A SEMA5B SEMA5B EFNB1 EFNB1 PLXNA4 PLXNA4 ENAH ENAH M3XYN0_MUSPF M3XYN0_MUSPF UNC5B UNC5B TRPC5 TRPC5 SEMA6C SEMA6C PAK3 PAK3 PAK2 PAK2 SSH3 SSH3 RHOD RHOD PPP3CC PPP3CC PPP3CB PPP3CB SSH1 SSH1 CAMK2G CAMK2G GNAI3 GNAI3 CSDE1 CSDE1 MAPK1 MAPK1 PLXNA2 PLXNA2 EPHB3 EPHB3 M3XUB5_MUSPF M3XUB5_MUSPF EPHA6 EPHA6 PTPN11 PTPN11 RRAS RRAS PLXNB2 PLXNB2 CXCR4 CXCR4 BMPR1B BMPR1B UNC5C UNC5C ABLIM1 ABLIM1 PTK2 PTK2 M3XRJ3_MUSPF M3XRJ3_MUSPF EPHA5 EPHA5 FZD3 FZD3 DPYSL2 DPYSL2 PDK1 PDK1 SEMA6A SEMA6A BMPR2 BMPR2 BOC BOC NTNG1 NTNG1 TRPC7 TRPC7 PLXNA3 PLXNA3 PPP3CA PPP3CA RYK RYK EPHB1 EPHB1 NCK1 NCK1 PLCG2 PLCG2 PIK3CB PIK3CB EPHA7 EPHA7 DPYSL5 DPYSL5 EFNB3 EFNB3 L1CAM L1CAM PLXNB3 PLXNB3 EPHB6 EPHB6 SEMA4D SEMA4D PAK6 PAK6 GSK3B GSK3B SRMS SRMS CDK5 CDK5 SEMA4F SEMA4F PTK6 PTK6 M3YA76_MUSPF M3YA76_MUSPF EPHA3 EPHA3 RASA1 RASA1 RGS3 RGS3 PRKCZ PRKCZ M3Y7P8_MUSPF M3Y7P8_MUSPF M3Y7N6_MUSPF M3Y7N6_MUSPF TRPC6 TRPC6 MET MET NTN4 NTN4 EPHA1 EPHA1 NFATC3 NFATC3 PTCH1 PTCH1 LRRC4 LRRC4 BMP7 BMP7 PAK5 PAK5 PARD6A PARD6A M3Y4E6_MUSPF M3Y4E6_MUSPF PIK3CD PIK3CD ROBO3 ROBO3 PARD3 PARD3 NRP1 NRP1 ITGB1 ITGB1 SMO SMO ADAM15 ADAM15 EFNA4 EFNA4 EPHA8 EPHA8 PAK1 PAK1 EPHB2 EPHB2 EPHB4 EPHB4 SEMA4B SEMA4B M3YWA8_MUSPF M3YWA8_MUSPF FES FES NTN3 NTN3 TRPC4 TRPC4 ROBO1 ROBO1 PLXNB1 PLXNB1 PIK3R1 PIK3R1 PRKCA PRKCA CCDC125 CCDC125 EPHA10 EPHA10 ABLIM3 ABLIM3 M3YR72_MUSPF M3YR72_MUSPF SSH2 SSH2 CAMK2A CAMK2A ARSI ARSI RHOA RHOA LDAH LDAH GDF7 GDF7 ROCK2 ROCK2 SEMA3F SEMA3F GNAI2 GNAI2 SEMA3B SEMA3B SLIT3 SLIT3 M3YNJ8_MUSPF M3YNJ8_MUSPF LIMK2 LIMK2 RAC2 RAC2 ABL1 ABL1 MAPK3 MAPK3 NTNG2 NTNG2 UNC5A UNC5A M3YLR8_MUSPF M3YLR8_MUSPF M3YKW7_MUSPF M3YKW7_MUSPF LRRC4C LRRC4C SEMA3D SEMA3D SEMA3A SEMA3A SEMA3E SEMA3E SEMA3C SEMA3C GNAI1 GNAI1 CAMK2B CAMK2B WNT5B WNT5B MYL9 MYL9 SRC SRC PAK4 PAK4 PLCG1 PLCG1 RGMA RGMA PARD6B PARD6B NFATC2 NFATC2 TRPC3 TRPC3 PLXNA1 PLXNA1 CXCL12 CXCL12 SEMA7A SEMA7A PIK3CA PIK3CA NEO1 NEO1 RAF1 RAF1 SRGAP3 SRGAP3 SLIT1 SLIT1 SEMA4G SEMA4G WNT5A WNT5A SEMA3G SEMA3G SLIT2 SLIT2 SRGAP1 SRGAP1 EPHA4 EPHA4 RAC1 RAC1 EPHA2 EPHA2 CFL2 CFL2 LIMK1 LIMK1 M3YX33_MUSPF M3YX33_MUSPF WNT4 WNT4 TRPC1 TRPC1 CFL1 CFL1 MYL5 MYL5 SEMA4C SEMA4C SEMA5A SEMA5A EFNB2 EFNB2 RAC3 RAC3 SEMA6D SEMA6D NCK2 NCK2 M3YH29_MUSPF M3YH29_MUSPF M3YGY7_MUSPF M3YGY7_MUSPF ROBO2 ROBO2 EFNA5 EFNA5 DCC DCC ABLIM2 ABLIM2 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FYNTyrosine-protein kinase. (537 aa)
UNC5DUnc-5 netrin receptor D. (878 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (193 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (175 aa)
NFATC4Nuclear factor of activated T cells 4. (831 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
ILKIntegrin linked kinase. (452 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
NGEFNeuronal guanine nucleotide exchange factor. (714 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (690 aa)
MYL12AMyosin light chain 12A. (172 aa)
MYL12BMyosin light chain 12B. (172 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
SEMA5BSemaphorin 5B. (1093 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
PLXNA4Plexin A4. (1893 aa)
ENAHENAH actin regulator. (817 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (936 aa)
PAK3P21 (RAC1) activated kinase 3. (583 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
SSH3Slingshot protein phosphatase 3. (650 aa)
RHODRas homolog family member D. (210 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
SSH1Slingshot protein phosphatase 1. (1013 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (561 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CSDE1Cold shock domain containing E1. (784 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PLXNA2Plexin A2. (1909 aa)
EPHB3EPH receptor B3. (959 aa)
M3XUB5_MUSPFEph LBD domain-containing protein. (381 aa)
EPHA6EPH receptor A6. (752 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
RRASRAS related. (218 aa)
PLXNB2Plexin B2. (1841 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
UNC5CUnc-5 netrin receptor C. (977 aa)
ABLIM1Actin binding LIM protein 1. (625 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
M3XRJ3_MUSPFUncharacterized protein. (182 aa)
EPHA5EPH receptor A5. (1037 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
DPYSL2Dihydropyrimidinase like 2. (572 aa)
PDK1Protein-serine/threonine kinase. (378 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1031 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1111 aa)
NTNG1Netrin G1. (581 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (807 aa)
PLXNA3Plexin A3. (1872 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
RYKReceptor like tyrosine kinase. (478 aa)
EPHB1EPH receptor B1. (984 aa)
NCK1Cytoplasmic protein. (378 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
EPHA7EPH receptor A7. (998 aa)
DPYSL5Dihydropyrimidinase like 5. (573 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
L1CAML1 cell adhesion molecule. (1340 aa)
PLXNB3Plexin B3. (1894 aa)
EPHB6EPH receptor B6. (1011 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
PAK6Non-specific serine/threonine protein kinase. (688 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
SRMSTyrosine-protein kinase. (507 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
PTK6Tyrosine-protein kinase. (444 aa)
M3YA76_MUSPFProtein kinase domain-containing protein. (533 aa)
EPHA3EPH receptor A3. (1000 aa)
RASA1RAS p21 protein activator 1. (1042 aa)
RGS3Regulator of G protein signaling 3. (1060 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
M3Y7P8_MUSPFSema domain-containing protein. (708 aa)
M3Y7N6_MUSPFUncharacterized protein. (568 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
NTN4Netrin 4. (590 aa)
EPHA1EPH receptor A1. (976 aa)
NFATC3Nuclear factor of activated T cells 3. (1037 aa)
PTCH1Patched 1. (1386 aa)
LRRC4Leucine rich repeat containing 4. (632 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ROBO3Roundabout guidance receptor 3. (1398 aa)
PARD3Par-3 family cell polarity regulator. (1356 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
ADAM15ADAM metallopeptidase domain 15. (860 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (166 aa)
EPHA8EPH receptor A8. (930 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
EPHB2EPH receptor B2. (963 aa)
EPHB4EPH receptor B4. (987 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (831 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
NTN3Netrin 3. (577 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
ROBO1Roundabout guidance receptor 1. (1683 aa)
PLXNB1Plexin B1. (2137 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
CCDC125Coiled-coil domain containing 125. (513 aa)
EPHA10EPH receptor A10. (1009 aa)
ABLIM3Actin binding LIM protein family member 3. (674 aa)
M3YR72_MUSPFUncharacterized protein. (542 aa)
SSH2Slingshot protein phosphatase 2. (1414 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (679 aa)
ARSIArylsulfatase family member I. (575 aa)
RHOARas homolog family member A. (193 aa)
LDAHLipid droplet associated hydrolase. (325 aa)
GDF7Growth differentiation factor 7. (382 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
GNAI2G protein subunit alpha i2. (355 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (748 aa)
SLIT3Slit guidance ligand 3. (1391 aa)
M3YNJ8_MUSPFUncharacterized protein. (461 aa)
LIMK2LIM domain kinase 2. (693 aa)
RAC2Rac family small GTPase 2. (192 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
NTNG2Netrin G2. (531 aa)
UNC5AUnc-5 netrin receptor A. (885 aa)
M3YLR8_MUSPFRHD domain-containing protein. (249 aa)
M3YKW7_MUSPFUncharacterized protein. (1071 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
GNAI1G protein subunit alpha i1. (354 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (610 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (406 aa)
MYL9Myosin light chain 9. (172 aa)
SRCTyrosine-protein kinase. (536 aa)
PAK4Non-specific serine/threonine protein kinase. (592 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (455 aa)
PARD6BPar-6 family cell polarity regulator beta. (391 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (866 aa)
PLXNA1Plexin A1. (1912 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (93 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (663 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NEO1Neogenin 1. (1419 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1075 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (840 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (770 aa)
SLIT2Slit guidance ligand 2. (1539 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
EPHA4EPH receptor A4. (986 aa)
RAC1Rac family small GTPase 1. (167 aa)
EPHA2EPH receptor A2. (975 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
LIMK1LIM domain kinase 1. (626 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa)
MYL5Myosin light chain 5. (172 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (867 aa)
SEMA5ASemaphorin 5A. (1073 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
RAC3Rac family small GTPase 3. (160 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1082 aa)
NCK2Cytoplasmic protein. (380 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
M3YGY7_MUSPFIg-like domain-containing protein. (131 aa)
ROBO2Roundabout guidance receptor 2. (1388 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (260 aa)
DCCDCC netrin 1 receptor. (1168 aa)
ABLIM2Actin binding LIM protein family member 2. (687 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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